JPS5599197A - Preparation of colistin heptapeptide - Google Patents

Preparation of colistin heptapeptide

Info

Publication number
JPS5599197A
JPS5599197A JP669779A JP669779A JPS5599197A JP S5599197 A JPS5599197 A JP S5599197A JP 669779 A JP669779 A JP 669779A JP 669779 A JP669779 A JP 669779A JP S5599197 A JPS5599197 A JP S5599197A
Authority
JP
Japan
Prior art keywords
colistin
heptapeptide
proteinase
preparation
hydrolyzing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP669779A
Other languages
Japanese (ja)
Other versions
JPS6216640B2 (en
Inventor
Mikiko Kagawa
Yasuo Koyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAYAKU ANTIBIOTIC RESEARCH CO
KAYAKU KK
Original Assignee
KAYAKU ANTIBIOTIC RESEARCH CO
KAYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAYAKU ANTIBIOTIC RESEARCH CO, KAYAKU KK filed Critical KAYAKU ANTIBIOTIC RESEARCH CO
Priority to JP669779A priority Critical patent/JPS5599197A/en
Publication of JPS5599197A publication Critical patent/JPS5599197A/en
Publication of JPS6216640B2 publication Critical patent/JPS6216640B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE:To prepare colistin heptapeptide having antibacterial spectrum differlnt from that of colistin, by severing the combination site of the cyclic with chain parts, using a proteinase (an enzyme hydrolyzing the colistin). CONSTITUTION:Colistin-producing bacteria, e.g. Bacillus polymyxavar colistinus, are incubated to collect a proteinase hydrolyzing colistin from the culture. The proteinase is then made to act on colistin or its sulfate to form colistin heptapeptide of the formula (DAB is alpha,beta-diamino butyric acid; Thr is threonine; Leu is leucine).
JP669779A 1979-01-23 1979-01-23 Preparation of colistin heptapeptide Granted JPS5599197A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP669779A JPS5599197A (en) 1979-01-23 1979-01-23 Preparation of colistin heptapeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP669779A JPS5599197A (en) 1979-01-23 1979-01-23 Preparation of colistin heptapeptide

Publications (2)

Publication Number Publication Date
JPS5599197A true JPS5599197A (en) 1980-07-28
JPS6216640B2 JPS6216640B2 (en) 1987-04-14

Family

ID=11645518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP669779A Granted JPS5599197A (en) 1979-01-23 1979-01-23 Preparation of colistin heptapeptide

Country Status (1)

Country Link
JP (1) JPS5599197A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109055288A (en) * 2018-06-30 2018-12-21 浙江工业大学 A kind of recombined bacillus subtilis and its application
CN110484467A (en) * 2019-08-19 2019-11-22 山东宝来利来生物工程股份有限公司 Antibacterial peptide and the application of one plant of bacillus polymyxa and its generation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109055288A (en) * 2018-06-30 2018-12-21 浙江工业大学 A kind of recombined bacillus subtilis and its application
CN110484467A (en) * 2019-08-19 2019-11-22 山东宝来利来生物工程股份有限公司 Antibacterial peptide and the application of one plant of bacillus polymyxa and its generation
CN110484467B (en) * 2019-08-19 2020-11-20 山东宝来利来生物工程股份有限公司 Bacillus polymyxa, antibacterial peptide produced by same and application of antibacterial peptide

Also Published As

Publication number Publication date
JPS6216640B2 (en) 1987-04-14

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