JPS5592365A - Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation - Google Patents

Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation

Info

Publication number
JPS5592365A
JPS5592365A JP15054578A JP15054578A JPS5592365A JP S5592365 A JPS5592365 A JP S5592365A JP 15054578 A JP15054578 A JP 15054578A JP 15054578 A JP15054578 A JP 15054578A JP S5592365 A JPS5592365 A JP S5592365A
Authority
JP
Japan
Prior art keywords
acylpyrrole
derivative
substituted
preparation
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15054578A
Other languages
Japanese (ja)
Inventor
Toshio Tanaka
Toshio Wakabayashi
Seiji Kurozumi
Akira Otsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP15054578A priority Critical patent/JPS5592365A/en
Publication of JPS5592365A publication Critical patent/JPS5592365A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A 1-substituted-3-acylpyrrole derivative of formula I [ϕis phenyl substituted optionally, 5W6C cycloalkyl, 5W6C cycloalkenyl, etc.; R1 is H or 1W4C alkyl; R2 is -X-R5 (X is O, S, etc.; R5 is H, 1W4C alkyl, OH, etc.), 1W4C alkoxy, etc.; R3 is H, 1W4C alkyl or form =0 in cooperation with R2; R4 is H, 1W 4C alkyl, etc.].
EXAMPLE: 2-(3-Benzoyl-2,5-dimethyl(pyrrol-1-y1)-2-methylethanol.
USE: A blood platelet anticoagulation agent , having a low antiinflammatory effect, though an acylpyrrole derivative, preventing or inhibiting the thrombus formation.
PREPARATION: The compound of formula II is reacted with an anhydride or halide of the acid of formula III, and further, if necessary, by hydrolysis, oxidation, or amidation, to obtain the title compound.
COPYRIGHT: (C)1980,JPO&Japio
JP15054578A 1978-12-07 1978-12-07 Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation Pending JPS5592365A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15054578A JPS5592365A (en) 1978-12-07 1978-12-07 Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15054578A JPS5592365A (en) 1978-12-07 1978-12-07 Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation

Publications (1)

Publication Number Publication Date
JPS5592365A true JPS5592365A (en) 1980-07-12

Family

ID=15499205

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15054578A Pending JPS5592365A (en) 1978-12-07 1978-12-07 Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation

Country Status (1)

Country Link
JP (1) JPS5592365A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1170361A (en) * 1997-08-29 1999-03-16 Daiwa Seiko Inc Tubular body and its manufacture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1170361A (en) * 1997-08-29 1999-03-16 Daiwa Seiko Inc Tubular body and its manufacture

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