JPS5592365A - Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation - Google Patents
Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparationInfo
- Publication number
- JPS5592365A JPS5592365A JP15054578A JP15054578A JPS5592365A JP S5592365 A JPS5592365 A JP S5592365A JP 15054578 A JP15054578 A JP 15054578A JP 15054578 A JP15054578 A JP 15054578A JP S5592365 A JPS5592365 A JP S5592365A
- Authority
- JP
- Japan
- Prior art keywords
- acylpyrrole
- derivative
- substituted
- preparation
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A 1-substituted-3-acylpyrrole derivative of formula I [ϕis phenyl substituted optionally, 5W6C cycloalkyl, 5W6C cycloalkenyl, etc.; R1 is H or 1W4C alkyl; R2 is -X-R5 (X is O, S, etc.; R5 is H, 1W4C alkyl, OH, etc.), 1W4C alkoxy, etc.; R3 is H, 1W4C alkyl or form =0 in cooperation with R2; R4 is H, 1W 4C alkyl, etc.].
EXAMPLE: 2-(3-Benzoyl-2,5-dimethyl(pyrrol-1-y1)-2-methylethanol.
USE: A blood platelet anticoagulation agent , having a low antiinflammatory effect, though an acylpyrrole derivative, preventing or inhibiting the thrombus formation.
PREPARATION: The compound of formula II is reacted with an anhydride or halide of the acid of formula III, and further, if necessary, by hydrolysis, oxidation, or amidation, to obtain the title compound.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15054578A JPS5592365A (en) | 1978-12-07 | 1978-12-07 | Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15054578A JPS5592365A (en) | 1978-12-07 | 1978-12-07 | Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5592365A true JPS5592365A (en) | 1980-07-12 |
Family
ID=15499205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15054578A Pending JPS5592365A (en) | 1978-12-07 | 1978-12-07 | Novel 1-substituted-3-acylpyrrole derivative, blood platelet anticoagulation agent containing it as active constituent, and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5592365A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1170361A (en) * | 1997-08-29 | 1999-03-16 | Daiwa Seiko Inc | Tubular body and its manufacture |
-
1978
- 1978-12-07 JP JP15054578A patent/JPS5592365A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1170361A (en) * | 1997-08-29 | 1999-03-16 | Daiwa Seiko Inc | Tubular body and its manufacture |
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