JPS5583739A - Preparation of polypeptide - Google Patents
Preparation of polypeptideInfo
- Publication number
- JPS5583739A JPS5583739A JP15789878A JP15789878A JPS5583739A JP S5583739 A JPS5583739 A JP S5583739A JP 15789878 A JP15789878 A JP 15789878A JP 15789878 A JP15789878 A JP 15789878A JP S5583739 A JPS5583739 A JP S5583739A
- Authority
- JP
- Japan
- Prior art keywords
- endorphin
- protected
- heptadecapeptide
- thr
- condensing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108010041395 alpha-Endorphin Proteins 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 108010047064 gamma-Endorphin Proteins 0.000 abstract 2
- NXSIJWJXMWBCBX-NWKQFZAZSA-N α-endorphin Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 NXSIJWJXMWBCBX-NWKQFZAZSA-N 0.000 abstract 2
- GASYAMBJHBRTOE-WHDBNHDESA-N γ-endorphin Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 GASYAMBJHBRTOE-WHDBNHDESA-N 0.000 abstract 2
- BQBCIBCLXBKYHW-CSMHCCOUSA-N Thr-Leu Chemical group CC(C)C[C@@H](C([O-])=O)NC(=O)[C@@H]([NH3+])[C@@H](C)O BQBCIBCLXBKYHW-CSMHCCOUSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15789878A JPS5583739A (en) | 1978-12-18 | 1978-12-18 | Preparation of polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15789878A JPS5583739A (en) | 1978-12-18 | 1978-12-18 | Preparation of polypeptide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5583739A true JPS5583739A (en) | 1980-06-24 |
| JPS6126920B2 JPS6126920B2 (enrdf_load_stackoverflow) | 1986-06-23 |
Family
ID=15659825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15789878A Granted JPS5583739A (en) | 1978-12-18 | 1978-12-18 | Preparation of polypeptide |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5583739A (enrdf_load_stackoverflow) |
-
1978
- 1978-12-18 JP JP15789878A patent/JPS5583739A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6126920B2 (enrdf_load_stackoverflow) | 1986-06-23 |
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