JPS5573644A - Addition compound of dipeptide ester with amino acid ester - Google Patents

Addition compound of dipeptide ester with amino acid ester

Info

Publication number
JPS5573644A
JPS5573644A JP14713878A JP14713878A JPS5573644A JP S5573644 A JPS5573644 A JP S5573644A JP 14713878 A JP14713878 A JP 14713878A JP 14713878 A JP14713878 A JP 14713878A JP S5573644 A JPS5573644 A JP S5573644A
Authority
JP
Japan
Prior art keywords
optically active
amino acid
compound
ester
addition compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14713878A
Other languages
Japanese (ja)
Other versions
JPS5835985B2 (en
Inventor
Kiyotaka Koyama
Yuji Nonaka
Mikio Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Tosoh Corp
Original Assignee
Sagami Chemical Research Institute
Toyo Soda Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute, Toyo Soda Manufacturing Co Ltd filed Critical Sagami Chemical Research Institute
Priority to JP53147138A priority Critical patent/JPS5835985B2/en
Publication of JPS5573644A publication Critical patent/JPS5573644A/en
Publication of JPS5835985B2 publication Critical patent/JPS5835985B2/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:A compound I (X is benzyloxycarbonyl which may have nucleus- substitution group; Y is side chain group of amino acid; R and R' are lower alkyl, and when Y is benyl, R is different from R').
EXAMPLE: The addition compound of N-benzyloxycarbonyl-L-aspartyl-L-phenylalanine ethyl ester and phenylalanine methyl ester.
USE: Intermediates of optically active amino acid esters useful as raw material for synthetic sweetening, etc. and those of optically active amino acides useful as nutriments for animals and as raw materials for antibiotics, etc. The optical resolution of a racemic amino acid ester can be easily carried out by using the compound of the invention as an intermediate.
PROCESS: An optically active compound II (e.g. LL-form) is reacted with a recemic modification III in a solvent to give preferentially or predominantly the optically active addition compound IV comprising the optically active form II and its antipode III (e.g. D-form).
COPYRIGHT: (C)1980,JPO&Japio
JP53147138A 1978-11-30 1978-11-30 Addition compound of dipeptide ester and amino acid ester Expired JPS5835985B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP53147138A JPS5835985B2 (en) 1978-11-30 1978-11-30 Addition compound of dipeptide ester and amino acid ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53147138A JPS5835985B2 (en) 1978-11-30 1978-11-30 Addition compound of dipeptide ester and amino acid ester

Publications (2)

Publication Number Publication Date
JPS5573644A true JPS5573644A (en) 1980-06-03
JPS5835985B2 JPS5835985B2 (en) 1983-08-05

Family

ID=15423425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53147138A Expired JPS5835985B2 (en) 1978-11-30 1978-11-30 Addition compound of dipeptide ester and amino acid ester

Country Status (1)

Country Link
JP (1) JPS5835985B2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2053188A1 (en) * 1970-10-29 1972-05-04 Ajinomoto Co , Ine , Tokio, G D Searle E W , Skokie, 111 (V St A ) Aspartyl phenyl alanine esters as sweet - ening agents
JPS5392779A (en) * 1977-01-12 1978-08-15 Montedison Spa Quarternary reaction between n*n**dimethyy1*4** dipyridinium dihalide and dipyridylacetate in acetic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2053188A1 (en) * 1970-10-29 1972-05-04 Ajinomoto Co , Ine , Tokio, G D Searle E W , Skokie, 111 (V St A ) Aspartyl phenyl alanine esters as sweet - ening agents
JPS5392779A (en) * 1977-01-12 1978-08-15 Montedison Spa Quarternary reaction between n*n**dimethyy1*4** dipyridinium dihalide and dipyridylacetate in acetic acid

Also Published As

Publication number Publication date
JPS5835985B2 (en) 1983-08-05

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