JPS5573644A - Addition compound of dipeptide ester with amino acid ester - Google Patents
Addition compound of dipeptide ester with amino acid esterInfo
- Publication number
- JPS5573644A JPS5573644A JP14713878A JP14713878A JPS5573644A JP S5573644 A JPS5573644 A JP S5573644A JP 14713878 A JP14713878 A JP 14713878A JP 14713878 A JP14713878 A JP 14713878A JP S5573644 A JPS5573644 A JP S5573644A
- Authority
- JP
- Japan
- Prior art keywords
- optically active
- amino acid
- compound
- ester
- addition compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A compound I (X is benzyloxycarbonyl which may have nucleus- substitution group; Y is side chain group of amino acid; R and R' are lower alkyl, and when Y is benyl, R is different from R').
EXAMPLE: The addition compound of N-benzyloxycarbonyl-L-aspartyl-L-phenylalanine ethyl ester and phenylalanine methyl ester.
USE: Intermediates of optically active amino acid esters useful as raw material for synthetic sweetening, etc. and those of optically active amino acides useful as nutriments for animals and as raw materials for antibiotics, etc. The optical resolution of a racemic amino acid ester can be easily carried out by using the compound of the invention as an intermediate.
PROCESS: An optically active compound II (e.g. LL-form) is reacted with a recemic modification III in a solvent to give preferentially or predominantly the optically active addition compound IV comprising the optically active form II and its antipode III (e.g. D-form).
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53147138A JPS5835985B2 (en) | 1978-11-30 | 1978-11-30 | Addition compound of dipeptide ester and amino acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53147138A JPS5835985B2 (en) | 1978-11-30 | 1978-11-30 | Addition compound of dipeptide ester and amino acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5573644A true JPS5573644A (en) | 1980-06-03 |
JPS5835985B2 JPS5835985B2 (en) | 1983-08-05 |
Family
ID=15423425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53147138A Expired JPS5835985B2 (en) | 1978-11-30 | 1978-11-30 | Addition compound of dipeptide ester and amino acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5835985B2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2053188A1 (en) * | 1970-10-29 | 1972-05-04 | Ajinomoto Co , Ine , Tokio, G D Searle E W , Skokie, 111 (V St A ) | Aspartyl phenyl alanine esters as sweet - ening agents |
JPS5392779A (en) * | 1977-01-12 | 1978-08-15 | Montedison Spa | Quarternary reaction between n*n**dimethyy1*4** dipyridinium dihalide and dipyridylacetate in acetic acid |
-
1978
- 1978-11-30 JP JP53147138A patent/JPS5835985B2/en not_active Expired
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2053188A1 (en) * | 1970-10-29 | 1972-05-04 | Ajinomoto Co , Ine , Tokio, G D Searle E W , Skokie, 111 (V St A ) | Aspartyl phenyl alanine esters as sweet - ening agents |
JPS5392779A (en) * | 1977-01-12 | 1978-08-15 | Montedison Spa | Quarternary reaction between n*n**dimethyy1*4** dipyridinium dihalide and dipyridylacetate in acetic acid |
Also Published As
Publication number | Publication date |
---|---|
JPS5835985B2 (en) | 1983-08-05 |
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