JPS5555185A - Extracting method of picrasma quassioides benn. - Google Patents

Extracting method of picrasma quassioides benn.

Info

Publication number
JPS5555185A
JPS5555185A JP12216678A JP12216678A JPS5555185A JP S5555185 A JPS5555185 A JP S5555185A JP 12216678 A JP12216678 A JP 12216678A JP 12216678 A JP12216678 A JP 12216678A JP S5555185 A JPS5555185 A JP S5555185A
Authority
JP
Japan
Prior art keywords
extract
picrasma quassioides
compound
benn
formyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12216678A
Other languages
Japanese (ja)
Other versions
JPS5612635B2 (en
Inventor
Shingo Matsumura
Hiroshi Enomoto
Yoshiaki Aoyanagi
Sumitsugu Nomiyama
Tatsuhiko Kono
Masato Matsuda
Haruo Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP12216678A priority Critical patent/JPS5555185A/en
Publication of JPS5555185A publication Critical patent/JPS5555185A/en
Publication of JPS5612635B2 publication Critical patent/JPS5612635B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PURPOSE: To extract and separate a specific indole derivative useful as a xanthine oxidase inhibitor, by the column chromatographic treatment of the extract of Picrasma quassioides Benn. known as a bitter stomachic.
CONSTITUTION: Dried powder of Picrasma quassioides is extracted with a polar organic solvent, and concentrated to obtain the whole extract of Picrasma quassioides. The extract is fractionated by column chromatography using H-type Sephadex or silica gel as adsorbent, and if necessary, purified to afford compounds I and II (R is carboxymethoxy, or formyl). The compound I wherein R is formyl is novel compound having excellent xanthine oxidase inhibiting activity. Useful as a preventive and remedy for gout. Combined use of the compound with a carcinostatic agent such as mitomycin C remarkably improves the carcinostatic activity.
COPYRIGHT: (C)1980,JPO&Japio
JP12216678A 1978-10-03 1978-10-03 Extracting method of picrasma quassioides benn. Granted JPS5555185A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12216678A JPS5555185A (en) 1978-10-03 1978-10-03 Extracting method of picrasma quassioides benn.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12216678A JPS5555185A (en) 1978-10-03 1978-10-03 Extracting method of picrasma quassioides benn.

Publications (2)

Publication Number Publication Date
JPS5555185A true JPS5555185A (en) 1980-04-22
JPS5612635B2 JPS5612635B2 (en) 1981-03-23

Family

ID=14829206

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12216678A Granted JPS5555185A (en) 1978-10-03 1978-10-03 Extracting method of picrasma quassioides benn.

Country Status (1)

Country Link
JP (1) JPS5555185A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686125A (en) * 2018-07-27 2018-10-23 兴义市付氏养殖农民专业合作社 A kind of sika deer bone health liquor that treating foot gout and its processing method
CN108704108A (en) * 2018-08-17 2018-10-26 公安县中医医院 A kind of medicine pill for treating gout

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02111768U (en) * 1989-02-23 1990-09-06
JPH02111769U (en) * 1989-02-23 1990-09-06

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686125A (en) * 2018-07-27 2018-10-23 兴义市付氏养殖农民专业合作社 A kind of sika deer bone health liquor that treating foot gout and its processing method
CN108704108A (en) * 2018-08-17 2018-10-26 公安县中医医院 A kind of medicine pill for treating gout

Also Published As

Publication number Publication date
JPS5612635B2 (en) 1981-03-23

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