JPS5555185A - Extracting method of picrasma quassioides benn. - Google Patents
Extracting method of picrasma quassioides benn.Info
- Publication number
- JPS5555185A JPS5555185A JP12216678A JP12216678A JPS5555185A JP S5555185 A JPS5555185 A JP S5555185A JP 12216678 A JP12216678 A JP 12216678A JP 12216678 A JP12216678 A JP 12216678A JP S5555185 A JPS5555185 A JP S5555185A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- picrasma quassioides
- compound
- benn
- formyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
PURPOSE: To extract and separate a specific indole derivative useful as a xanthine oxidase inhibitor, by the column chromatographic treatment of the extract of Picrasma quassioides Benn. known as a bitter stomachic.
CONSTITUTION: Dried powder of Picrasma quassioides is extracted with a polar organic solvent, and concentrated to obtain the whole extract of Picrasma quassioides. The extract is fractionated by column chromatography using H-type Sephadex or silica gel as adsorbent, and if necessary, purified to afford compounds I and II (R is carboxymethoxy, or formyl). The compound I wherein R is formyl is novel compound having excellent xanthine oxidase inhibiting activity. Useful as a preventive and remedy for gout. Combined use of the compound with a carcinostatic agent such as mitomycin C remarkably improves the carcinostatic activity.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12216678A JPS5555185A (en) | 1978-10-03 | 1978-10-03 | Extracting method of picrasma quassioides benn. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12216678A JPS5555185A (en) | 1978-10-03 | 1978-10-03 | Extracting method of picrasma quassioides benn. |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5555185A true JPS5555185A (en) | 1980-04-22 |
JPS5612635B2 JPS5612635B2 (en) | 1981-03-23 |
Family
ID=14829206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12216678A Granted JPS5555185A (en) | 1978-10-03 | 1978-10-03 | Extracting method of picrasma quassioides benn. |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5555185A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108686125A (en) * | 2018-07-27 | 2018-10-23 | 兴义市付氏养殖农民专业合作社 | A kind of sika deer bone health liquor that treating foot gout and its processing method |
CN108704108A (en) * | 2018-08-17 | 2018-10-26 | 公安县中医医院 | A kind of medicine pill for treating gout |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02111768U (en) * | 1989-02-23 | 1990-09-06 | ||
JPH02111769U (en) * | 1989-02-23 | 1990-09-06 |
-
1978
- 1978-10-03 JP JP12216678A patent/JPS5555185A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108686125A (en) * | 2018-07-27 | 2018-10-23 | 兴义市付氏养殖农民专业合作社 | A kind of sika deer bone health liquor that treating foot gout and its processing method |
CN108704108A (en) * | 2018-08-17 | 2018-10-26 | 公安县中医医院 | A kind of medicine pill for treating gout |
Also Published As
Publication number | Publication date |
---|---|
JPS5612635B2 (en) | 1981-03-23 |
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