JPS55385A - Saccharide derivative of purine and its preparation - Google Patents

Saccharide derivative of purine and its preparation

Info

Publication number
JPS55385A
JPS55385A JP6236179A JP6236179A JPS55385A JP S55385 A JPS55385 A JP S55385A JP 6236179 A JP6236179 A JP 6236179A JP 6236179 A JP6236179 A JP 6236179A JP S55385 A JPS55385 A JP S55385A
Authority
JP
Japan
Prior art keywords
preparation
adenine
benzoyl
formula
purine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6236179A
Other languages
Japanese (ja)
Other versions
JPS5747200B2 (en
Inventor
Kiyoshi Isono
Tsunemasa Azuma
Saburo Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP6236179A priority Critical patent/JPS55385A/en
Publication of JPS55385A publication Critical patent/JPS55385A/en
Publication of JPS5747200B2 publication Critical patent/JPS5747200B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:9-β-(5-Amino-5-deoxy-D-allofuranosyluronic acid)adenine of the formula.
USE: An inhibitor against the enzyme hydrolyzing the phospho diester linkage in CAMP, CGMP (transmetters of hormone activities), being used for heart attack or diseases caused by deficiency in hormone balance.
PREPARATION: Polyoxin D, E, F that are produced by a specific Streptomyces is used as the starting material and subjected to several kinds of procedures to give 2',3'-di-O-acetyl-N3-benzoyl-N3'-carboxyuracilpolyoxin C methyl ester. Consequently, the reaction of the product with N6-benzoyl-N6,9-bistrimethylsilyl adenine is effected in the presence of an acidic catalyst and a solvent to form the compound of the formula.
COPYRIGHT: (C)1980,JPO&Japio
JP6236179A 1979-05-21 1979-05-21 Saccharide derivative of purine and its preparation Granted JPS55385A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6236179A JPS55385A (en) 1979-05-21 1979-05-21 Saccharide derivative of purine and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6236179A JPS55385A (en) 1979-05-21 1979-05-21 Saccharide derivative of purine and its preparation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP11744476A Division JPS5356690A (en) 1976-09-30 1976-09-30 Purin compund sugar derivatives and their preparation

Publications (2)

Publication Number Publication Date
JPS55385A true JPS55385A (en) 1980-01-05
JPS5747200B2 JPS5747200B2 (en) 1982-10-07

Family

ID=13197899

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6236179A Granted JPS55385A (en) 1979-05-21 1979-05-21 Saccharide derivative of purine and its preparation

Country Status (1)

Country Link
JP (1) JPS55385A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935184A (en) * 1972-02-22 1976-01-27 Syntex (U.S.A.) Inc. Synthetic polyoxin type nucleosides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935184A (en) * 1972-02-22 1976-01-27 Syntex (U.S.A.) Inc. Synthetic polyoxin type nucleosides

Also Published As

Publication number Publication date
JPS5747200B2 (en) 1982-10-07

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