JPS55348A - Antibiotic of cephalosporin analogue - Google Patents
Antibiotic of cephalosporin analogueInfo
- Publication number
- JPS55348A JPS55348A JP15803078A JP15803078A JPS55348A JP S55348 A JPS55348 A JP S55348A JP 15803078 A JP15803078 A JP 15803078A JP 15803078 A JP15803078 A JP 15803078A JP S55348 A JPS55348 A JP S55348A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- thienyl
- alpha
- compound
- cephalosporin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I (Ar is 2-thienyl, 3-thienyl, phenyl, p-alkanoyloxyphenyl, etc.; B<1> and B<2> are H, alkyl, aralkyl, aryl) or their salts. EXAMPLE:7beta-[alpha-Carboxy-alpha-(3-thienyl)acetamide]-7alpha-methox y-3-(1-methyltetrazole-5-yl)thiomethyl-1-oxadethia-3-cepham-4-carboxylic acid. USE:Antibacterial and bactericidal agent or their synthetic intermediates, being effective on both gram-positive and -negative bacteria and further on bacteria producing beta-lactamase and resisting cephalosporin. PREPARATION:The compound of formula II is made to react with a malonic derivative of formula III or its reactive derivative to produce the compound of formula I. The reaction is carried out in a solvent and, when necessary, a condensation agent, acid acceptor, and an organic base are added.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15803078A JPS55348A (en) | 1978-12-18 | 1978-12-18 | Antibiotic of cephalosporin analogue |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15803078A JPS55348A (en) | 1978-12-18 | 1978-12-18 | Antibiotic of cephalosporin analogue |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5029576A Division JPS52133997A (en) | 1976-03-25 | 1976-04-30 | Cephalosporin antibiotics |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55348A true JPS55348A (en) | 1980-01-05 |
Family
ID=15662730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15803078A Pending JPS55348A (en) | 1978-12-18 | 1978-12-18 | Antibiotic of cephalosporin analogue |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55348A (en) |
-
1978
- 1978-12-18 JP JP15803078A patent/JPS55348A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE790686L (en) | Penicillin derivatives | |
FI864825A (en) | CEFALOSPORINDERIVAT. | |
JPS55348A (en) | Antibiotic of cephalosporin analogue | |
GB1250611A (en) | ||
ATE13302T1 (en) | 3-O-DEMETHYL DERIVATIVES OF ISTAMYCIN B SERIES COMPOUNDS AND THEIR PRODUCTION. | |
GB1493197A (en) | Amides of clavulanic acid | |
JPS5643288A (en) | Cephalosporin derivative and its preparation | |
JPS5610165A (en) | Novel beta-lactam compound and its production | |
AU553027B2 (en) | 6alpha-methoxy penicillins | |
JPS5524135A (en) | Penicillin derivative and its preparation | |
IE43538L (en) | Cephalosporin derivatives. | |
SE7702481L (en) | PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS | |
JPS55145690A (en) | Novel penicillin and cephalosporin, and its salt | |
JPS5579392A (en) | Novel beta-lactam compound and its preparation | |
ES8100302A1 (en) | 7alphaamethoxycephalosporin and antibacterial | |
JPS54130594A (en) | Novel cephalosporin derivative | |
JPS5625154A (en) | Azetidinone derivative | |
JPS5718687A (en) | Penicillin derivative and its salt | |
JPS5625188A (en) | 7alpha-methoxycephalosporin | |
JPS5585593A (en) | Novel penicillin compound and its preparation | |
KR790000617B1 (en) | 7-(alph--furoyl ureidoaryl and cycloheydienylacemido) cephalosporin antibiotics | |
JPS5579394A (en) | Novel 7-methoxycephalosporin derivative | |
JPS5791990A (en) | 7alpha-methoxycephem derivative, its preparation and antimicrobial agent consisting of the same | |
SE7702558L (en) | PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS | |
JPS5748964A (en) | Pyridylsulfilimine derivative |