JPS5533479A - Novel benzimidazole - Google Patents
Novel benzimidazoleInfo
- Publication number
- JPS5533479A JPS5533479A JP10730779A JP10730779A JPS5533479A JP S5533479 A JPS5533479 A JP S5533479A JP 10730779 A JP10730779 A JP 10730779A JP 10730779 A JP10730779 A JP 10730779A JP S5533479 A JPS5533479 A JP S5533479A
- Authority
- JP
- Japan
- Prior art keywords
- novel benzimidazole
- benzimidazole
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F8/00—Arrangements for software engineering
- G06F8/30—Creation or generation of source code
- G06F8/31—Programming languages or programming paradigms
- G06F8/313—Logic programming, e.g. PROLOG programming language
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Software Systems (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Computing Systems (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782837161 DE2837161A1 (en) | 1978-08-25 | 1978-08-25 | 5-Alkyl:pyridazinyl substd. benzimidazole derivs. - useful as cardiovascular agents, antivirals, interferon inducers and ulcer inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5533479A true JPS5533479A (en) | 1980-03-08 |
JPS6324996B2 JPS6324996B2 (en) | 1988-05-23 |
Family
ID=6047905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10730779A Granted JPS5533479A (en) | 1978-08-25 | 1979-08-24 | Novel benzimidazole |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5533479A (en) |
DE (1) | DE2837161A1 (en) |
ZA (1) | ZA794472B (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61194083A (en) * | 1985-02-19 | 1986-08-28 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | Benzimidazolylpyridazinone compound |
JPH01254627A (en) * | 1988-02-24 | 1989-10-11 | Dr Karl Thomae Gmbh | Pharmaceutical composition |
JPH04210919A (en) * | 1990-01-20 | 1992-08-03 | Dr Karl Thomae Gmbh | Oral administrating preparation of pimobendan |
JP2006219452A (en) * | 2005-02-14 | 2006-08-24 | Toa Eiyo Ltd | Method for producing pimobendan and its intermediate |
JP2009504758A (en) * | 2005-08-15 | 2009-02-05 | アイアールエム・リミテッド・ライアビリティ・カンパニー | Compounds and compositions as TPO mimetics |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3804490A1 (en) * | 1988-02-12 | 1989-08-24 | Heumann Pharma Gmbh & Co | SUBSTITUTED 6-PHENYLDIHYDRO-3 (2H) -PYRIDAZINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
DE3814057A1 (en) * | 1988-04-26 | 1989-11-09 | Heumann Pharma Gmbh & Co | 6-OXO-PYRIDAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
DE3913597A1 (en) * | 1989-04-25 | 1990-11-08 | Heumann Pharma Gmbh & Co | DIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
NZ568694A (en) | 2005-11-09 | 2011-09-30 | Zalicus Inc | Method, compositions, and kits for the treatment of medical conditions |
WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
EA201391254A1 (en) | 2011-03-01 | 2014-02-28 | Синерджи Фармасьютикалз Инк. | METHOD FOR OBTAINING GUANYLATZCLAZE AGONISTS C |
EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
CA2902348C (en) | 2013-02-25 | 2021-11-30 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
WO2014197720A2 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
CN114340631A (en) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | Combination for reducing serum phosphate in a patient |
-
1978
- 1978-08-25 DE DE19782837161 patent/DE2837161A1/en not_active Withdrawn
-
1979
- 1979-08-24 JP JP10730779A patent/JPS5533479A/en active Granted
- 1979-08-24 ZA ZA00794472A patent/ZA794472B/en unknown
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61194083A (en) * | 1985-02-19 | 1986-08-28 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | Benzimidazolylpyridazinone compound |
JPH01254627A (en) * | 1988-02-24 | 1989-10-11 | Dr Karl Thomae Gmbh | Pharmaceutical composition |
JPH04210919A (en) * | 1990-01-20 | 1992-08-03 | Dr Karl Thomae Gmbh | Oral administrating preparation of pimobendan |
JP2608183B2 (en) * | 1990-01-20 | 1997-05-07 | ドクトル カルル トーマエ ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pimobendan oral dosage form |
JP2006219452A (en) * | 2005-02-14 | 2006-08-24 | Toa Eiyo Ltd | Method for producing pimobendan and its intermediate |
JP4714921B2 (en) * | 2005-02-14 | 2011-07-06 | トーアエイヨー株式会社 | Production method of pimobendan and its intermediate |
JP2009504758A (en) * | 2005-08-15 | 2009-02-05 | アイアールエム・リミテッド・ライアビリティ・カンパニー | Compounds and compositions as TPO mimetics |
Also Published As
Publication number | Publication date |
---|---|
ZA794472B (en) | 1981-04-29 |
JPS6324996B2 (en) | 1988-05-23 |
DE2837161A1 (en) | 1980-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EG13913A (en) | Novel n-heterocyclyl-4-piperidinamines | |
CS520079A2 (en) | Nosna soustava snimaci hlavice | |
JPS54122278A (en) | 99aminoodibenzopyranes | |
JPS5533479A (en) | Novel benzimidazole | |
ZA794379B (en) | Novel spiro-oxazolidindiones | |
BG27580A1 (en) | Two- poled pelvis- thight articulation- set | |
CS761579A2 (en) | Elektricky vypinac se samocinnym zhasenim elektrickeho oblouku | |
CS333379A2 (en) | Upinaci zarizeni | |
GB2025061B (en) | Hot-wireanemometer | |
CS353979A2 (en) | Zpusob extrakce organickych slozek z rostlinnych materialu | |
JPS54154730A (en) | Novel dialkoxybenzamides | |
CS290179A2 (en) | Plynova vybojka | |
JPS5549432A (en) | Scooperrexcavator | |
JPS54150667A (en) | Ptccresistor | |
PH17031A (en) | Novel phenoxyalkyloxazolines | |
GB2038323B (en) | N-acyl-o-phenylenediamines | |
JPS5555069A (en) | Autobicycle | |
HK42683A (en) | Phenoxyalkanamides | |
GB2024800B (en) | Glass-cutter | |
JPS54146422A (en) | Hhsteel | |
CS556679A2 (en) | Zpusob vyroby derivatu chlorambucilu | |
BG31541A1 (en) | Ornitopter | |
GB2027016B (en) | Substituted thio-sulphinyl-and sulphonyl-alkyl benzimidazole carbamates | |
CA43944S (en) | Compositiontable | |
CA44301S (en) | Hairsetter |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |