JPS5522698A - Preparation of maleimidobenzoic acid derivative - Google Patents
Preparation of maleimidobenzoic acid derivativeInfo
- Publication number
- JPS5522698A JPS5522698A JP10155679A JP10155679A JPS5522698A JP S5522698 A JPS5522698 A JP S5522698A JP 10155679 A JP10155679 A JP 10155679A JP 10155679 A JP10155679 A JP 10155679A JP S5522698 A JPS5522698 A JP S5522698A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- enzyme
- carboxylic acid
- acid derivative
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrrole Compounds (AREA)
Abstract
PURPOSE: To prepare the title derivative capable of selectively bonding an enzyme with an antigen, and useful as a bonding agent for the preparation of an enzyme- labelled antigen, by reacting a specific carboxylic acid, etc. with N-hydroxysuccinimide.
CONSTITUTION: A maleimidobenzoic acid derivative of formula III is prepared easily by reacting a carboxylic acid I or its reactive derivative at the carboxylic groups (e.g. a mixed anhydride or acid halide of isopropyl chlorocarbonate and the carboxylic acid I) with N-hydroxysuccinimide, pref. at 0W40°C for 20W240 minutes.
USE: Bonding agent for the preparation of an enzyme-labelled antigen useful for the trace analysis of hormones, etc. by enzyme immunoassay.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10155679A JPS588395B2 (en) | 1979-08-08 | 1979-08-08 | Method for producing maleimidobenzoic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10155679A JPS588395B2 (en) | 1979-08-08 | 1979-08-08 | Method for producing maleimidobenzoic acid derivatives |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50148787A Division JPS5272284A (en) | 1975-12-12 | 1975-12-12 | Enzymeeimmunoassay reagent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5522698A true JPS5522698A (en) | 1980-02-18 |
JPS588395B2 JPS588395B2 (en) | 1983-02-15 |
Family
ID=14303687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10155679A Expired JPS588395B2 (en) | 1979-08-08 | 1979-08-08 | Method for producing maleimidobenzoic acid derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS588395B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58208238A (en) * | 1982-03-17 | 1983-12-03 | サノフイ・ソシエテ・アノニム | Novel conjugate for bonding enzyme and antibody by conjugate bond and medicine |
JP2018155880A (en) * | 2017-03-16 | 2018-10-04 | 保土谷化学工業株式会社 | Charge control agents and toners using imidobenzoic acid derivatives |
-
1979
- 1979-08-08 JP JP10155679A patent/JPS588395B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58208238A (en) * | 1982-03-17 | 1983-12-03 | サノフイ・ソシエテ・アノニム | Novel conjugate for bonding enzyme and antibody by conjugate bond and medicine |
JP2018155880A (en) * | 2017-03-16 | 2018-10-04 | 保土谷化学工業株式会社 | Charge control agents and toners using imidobenzoic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS588395B2 (en) | 1983-02-15 |
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