JPS55167299A

JPS55167299A - 25-hydroperoxy-24-oxocholestane derivative

25-hydroperoxy-24-oxocholestane derivative

Info

Publication number: JPS55167299A
Authority: JP; Japan
Prior art keywords: oxocholestane; hydroperoxy; derivative; bond; formula
Prior art date: 1979-06-14
Legal status : Granted

Application number

JP7395679A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6220996B2 (enrdf_load_stackoverflow

Inventor

Osamu Nishikawa

Kenji Ishimaru

Toru Takeshita

Hideki Tsuruta

Current Assignee

Teijin Ltd

Original Assignee

Teijin Ltd

Priority date

1979-06-14

Filing date

1979-06-14

Publication date

1980-12-26

1979-06-14 Application filed by Teijin Ltd filed Critical Teijin Ltd

1979-06-14 Priority to JP7395679A priority Critical patent/JPS55167299A/ja

1980-02-14 Priority to CA000345624A priority patent/CA1138859A/en

1980-02-14 Priority to DE8080300426T priority patent/DE3064789D1/de

1980-02-14 Priority to DK063080A priority patent/DK162648C/da

1980-02-14 Priority to EP82200223A priority patent/EP0055999B1/en

1980-02-14 Priority to DE8282200223T priority patent/DE3069391D1/de

1980-02-14 Priority to EP80300426A priority patent/EP0015122B1/en

1980-02-15 Priority to US06/121,857 priority patent/US4292249A/en

1980-12-26 Publication of JPS55167299A publication Critical patent/JPS55167299A/ja

1985-05-24 Priority to DK233585A priority patent/DK233585D0/da

1987-05-11 Publication of JPS6220996B2 publication Critical patent/JPS6220996B2/ja

Status Granted legal-status Critical Current

Links

WSMIHAXRUXBPHY-BMXWGISTSA-N (6r)-6-[(8r,9s,10s,13r,14s,17r)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-hydroperoxy-2-methylheptan-3-one Chemical class C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](CCC(=O)C(C)(C)OO)C)[C@@]1(C)CC2 WSMIHAXRUXBPHY-BMXWGISTSA-N 0.000 title abstract 2
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
RLTGEIOMVFMKAH-QWMOJLDXSA-N (6r)-2-hydroperoxy-6-[(3s,8s,9s,10r,13r,14s,17r)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-one Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](CCC(=O)C(C)(C)OO)C)[C@@]1(C)CC2 RLTGEIOMVFMKAH-QWMOJLDXSA-N 0.000 abstract 1
VUPAQVVEERNKQJ-WOEDOHCHSA-N (6r)-6-[(8r,9s,10s,13r,14s,17r)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-one Chemical class C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCC(=O)C(C)C)[C@@]1(C)CC2 VUPAQVVEERNKQJ-WOEDOHCHSA-N 0.000 abstract 1
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000007514 bases Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 abstract 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000011647 vitamin D3 Substances 0.000 abstract 1
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 abstract 1