JPS5516434B2 - - Google Patents

Info

Publication number
JPS5516434B2
JPS5516434B2 JP1846373A JP1846373A JPS5516434B2 JP S5516434 B2 JPS5516434 B2 JP S5516434B2 JP 1846373 A JP1846373 A JP 1846373A JP 1846373 A JP1846373 A JP 1846373A JP S5516434 B2 JPS5516434 B2 JP S5516434B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP1846373A
Other languages
Japanese (ja)
Other versions
JPS4892400A (en:Method
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4892400A publication Critical patent/JPS4892400A/ja
Publication of JPS5516434B2 publication Critical patent/JPS5516434B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP1846373A 1972-02-23 1973-02-16 Expired JPS5516434B2 (en:Method)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00228743A US3833591A (en) 1972-02-23 1972-02-23 1,3,4,5-tetrahydropyrrolo(4,3,2-d,e)isoquinolines and related compounds

Publications (2)

Publication Number Publication Date
JPS4892400A JPS4892400A (en:Method) 1973-11-30
JPS5516434B2 true JPS5516434B2 (en:Method) 1980-05-01

Family

ID=22858420

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1846373A Expired JPS5516434B2 (en:Method) 1972-02-23 1973-02-16

Country Status (6)

Country Link
US (1) US3833591A (en:Method)
JP (1) JPS5516434B2 (en:Method)
BE (1) BE795451A (en:Method)
DE (1) DE2306605A1 (en:Method)
FR (1) FR2181738B1 (en:Method)
GB (1) GB1418354A (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5729817U (en:Method) * 1980-07-26 1982-02-17

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3900477A (en) * 1973-11-06 1975-08-19 Ayerst Mckenna & Harrison 5-amino-and 5-hydrazinodihydropyrroloisoquinoline derivatives
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
US3978066A (en) * 1973-11-06 1976-08-31 Ayerst, Mckenna And Harrison Ltd. Certain 4,6-dihydropyrrolotriazoline-quinoline derivatives
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4545935A (en) * 1983-09-12 1985-10-08 Iowa State University Research Foundation, Inc. Amidoalkylation reactions of anilines
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
ES2057121T3 (es) * 1988-06-01 1994-10-16 Smithkline Beecham Corp Antagonistas de los receptores alfa-adrenergicos.
NZ229300A (en) * 1988-06-01 1991-04-26 Smithkline Beckman Corp Substituted-2-ethenyl-3,4,5,6-tetrahydrothieno (4,3,2-cf)(3)benzazepine derivatives and pharmaceutical compositions
US5006521A (en) * 1988-06-01 1991-04-09 Smithkline Beecham Corporation α-adrenergic receptor antagonists and methods of use thereas
ATE114310T1 (de) * 1988-06-01 1994-12-15 Smithkline Beecham Corp Alpha-adrenergische rezeptorantagonisten.
US4978660A (en) * 1988-06-01 1990-12-18 Smithkline Beecham Corporation α-adrenergic receptor antagonists
US4963547A (en) * 1988-06-01 1990-10-16 Smithkline Beecham Corporation Alpha-andrenergic receptor antagonists and use thereas
EP0344980A3 (en) * 1988-06-01 1991-05-15 Smithkline Beecham Corporation Alpha-adrenergic receptor antagonists
US4959360A (en) * 1988-06-01 1990-09-25 Smithkline Beecham Corporation α-adrenergic receptor antagonists
US4981848A (en) * 1989-02-23 1991-01-01 Smithkline Beecham Corporation Alpha-adrenergic receptor antagonists
US4981849A (en) * 1989-02-23 1991-01-01 Smithkline Beecham Corporation Alpha-adrenergic receptor antagonists
US6765004B1 (en) * 1999-06-17 2004-07-20 Ortho-Mcneil Pharmaceutical, Inc. Indoloazepines as vasopressin receptor antagonists
EA016592B1 (ru) * 2007-03-13 2012-06-29 Биовитрум Аб (Пабл) Трициклические производные изохинолина для лечения ожирения
CN119504773B (zh) * 2024-10-30 2025-10-10 河北大学 吡咯并喹喔啉并稠杂氮杂糖衍生物及合成方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5729817U (en:Method) * 1980-07-26 1982-02-17

Also Published As

Publication number Publication date
JPS4892400A (en:Method) 1973-11-30
FR2181738B1 (en:Method) 1976-03-05
BE795451A (fr) 1973-08-16
GB1418354A (en) 1975-12-17
FR2181738A1 (en:Method) 1973-12-07
DE2306605A1 (de) 1973-09-06
US3833591A (en) 1974-09-03

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