JPS5515432A

JPS5515432A - Lactam compound

Lactam compound

Info

Publication number: JPS5515432A
Authority: JP; Japan
Prior art keywords: compound; formula; alkyl; acyl; phenyl group
Prior art date: 1978-07-17
Legal status : Granted

Application number

JP8753378A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6245863B2 (enrdf_load_stackoverflow

Inventor

Masayuki Imanishi

Yutaka Masuoka

Ryoko Nakajima

Current Assignee

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Chemical Industries Ltd

Priority date

1978-07-17

Filing date

1978-07-17

Publication date

1980-02-02

1978-07-17 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1978-07-17 Priority to JP8753378A priority Critical patent/JPS5515432A/ja

1978-09-27 Priority to AU40242/78A priority patent/AU518986B2/en

1978-10-04 Priority to DK439878A priority patent/DK439878A/da

1978-10-06 Priority to CA312,844A priority patent/CA1102338A/en

1978-10-07 Priority to EP78101094A priority patent/EP0001601B1/en

1978-10-07 Priority to DE7878101094T priority patent/DE2861210D1/de

1978-10-10 Priority to NO783420A priority patent/NO150041C/no

1978-10-10 Priority to IT28617/78A priority patent/IT1099358B/it

1978-10-11 Priority to US05/950,524 priority patent/US4198514A/en

1980-02-02 Publication of JPS5515432A publication Critical patent/JPS5515432A/ja

1987-09-29 Publication of JPS6245863B2 publication Critical patent/JPS6245863B2/ja

Status Granted legal-status Critical Current

Links

-1 Lactam compound Chemical class 0.000 title abstract 2
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
ZRNZFZGNDFKJQE-UHFFFAOYSA-N 4-[(4-chlorophenyl)methyl]pyrrolidin-2-one Chemical compound C1=CC(Cl)=CC=C1CC1CC(=O)NC1 ZRNZFZGNDFKJQE-UHFFFAOYSA-N 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
206010003840 Autonomic nervous system imbalance Diseases 0.000 abstract 1
201000004624 Dermatitis Diseases 0.000 abstract 1
208000035755 Psychosomatic disease Diseases 0.000 abstract 1
208000005392 Spasm Diseases 0.000 abstract 1
206010047700 Vomiting Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000001663 anti-spastic effect Effects 0.000 abstract 1
229940125713 antianxiety drug Drugs 0.000 abstract 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
230000000472 traumatic effect Effects 0.000 abstract 1
230000008673 vomiting Effects 0.000 abstract 1