JPS55136233A - Hb peptide vaccine - Google Patents
Hb peptide vaccineInfo
- Publication number
- JPS55136233A JPS55136233A JP4405879A JP4405879A JPS55136233A JP S55136233 A JPS55136233 A JP S55136233A JP 4405879 A JP4405879 A JP 4405879A JP 4405879 A JP4405879 A JP 4405879A JP S55136233 A JPS55136233 A JP S55136233A
- Authority
- JP
- Japan
- Prior art keywords
- hepatitis
- hbsag
- virus
- surface antigen
- antigenicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:HBsAg. A peptide having the following physico-chemical properties, obtained by heat-treating the surface antigen of hepatitis B virus in the presence of a surfactant and a reducing agent: Molecular weight 18,000W23,000. Solubility: about 5% or less in water near neutral, assuming a proteinous opaque color at a higher concentration. Ultraviolet adsorption: molecular extinction coefficient at 280nm of 38. Temperature stability: without loss of the antigenicity of an aqueous solution if heated at 60±0.5°C for 1hr. Constitutent amino acids: 17 amino acids, e.g., aspartic acid and threonine.
USE: Vaccines for hepatitis B. Low-molecular subunits capable of retaining the antigenicity of the surface antigen (HBsAg) of the hepatitis B virus (HBV).
PROCESS: The vaccine is obtained from blood plasma or serum comprising the surface antigen (HBsAg) of hepatitis B virus.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4405879A JPS55136233A (en) | 1979-04-11 | 1979-04-11 | Hb peptide vaccine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4405879A JPS55136233A (en) | 1979-04-11 | 1979-04-11 | Hb peptide vaccine |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP628688A Division JPS63239234A (en) | 1988-01-14 | 1988-01-14 | Vaccine preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55136233A true JPS55136233A (en) | 1980-10-23 |
JPS6212238B2 JPS6212238B2 (en) | 1987-03-17 |
Family
ID=12681007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4405879A Granted JPS55136233A (en) | 1979-04-11 | 1979-04-11 | Hb peptide vaccine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55136233A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60258127A (en) * | 1984-06-04 | 1985-12-20 | Green Cross Corp:The | Preparation of hepatitis b vaccine |
WO1995015497A1 (en) * | 1993-11-30 | 1995-06-08 | The University Of Queensland | Immunoassay for cervical cancer |
-
1979
- 1979-04-11 JP JP4405879A patent/JPS55136233A/en active Granted
Non-Patent Citations (2)
Title |
---|
JOUNAL OF VIROLOGY=1972 * |
PROC NATL ACAD SCI USA=1977 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60258127A (en) * | 1984-06-04 | 1985-12-20 | Green Cross Corp:The | Preparation of hepatitis b vaccine |
WO1995015497A1 (en) * | 1993-11-30 | 1995-06-08 | The University Of Queensland | Immunoassay for cervical cancer |
Also Published As
Publication number | Publication date |
---|---|
JPS6212238B2 (en) | 1987-03-17 |
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