JPS57175127A - Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen - Google Patents

Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen

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Publication number
JPS57175127A
JPS57175127A JP6022181A JP6022181A JPS57175127A JP S57175127 A JPS57175127 A JP S57175127A JP 6022181 A JP6022181 A JP 6022181A JP 6022181 A JP6022181 A JP 6022181A JP S57175127 A JPS57175127 A JP S57175127A
Authority
JP
Japan
Prior art keywords
nanb
hepatitis
viral
vaccine
hepatitis nanb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6022181A
Other languages
Japanese (ja)
Other versions
JPH0369892B2 (en
Inventor
Koji Yoshizawa
Tadashi Mayumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP6022181A priority Critical patent/JPS57175127A/en
Publication of JPS57175127A publication Critical patent/JPS57175127A/en
Publication of JPH0369892B2 publication Critical patent/JPH0369892B2/ja
Granted legal-status Critical Current

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To obtain the titled vaccine, having a high immunogenicity without infection, and useful for a detecting reagent of the titled viral antigen, by treating hepatitis NANB-1 and NANB-2 viral particles with an organic solvent, and heat-treating the particles.
CONSTITUTION: Viral particles, obtained from the blood serum of the hepatitis NANB-1 in the acute stadium, and found to be capable of agglutinating with the hepatitis NANB-1 blood serum in the decubation and infecting and developing the typical hepatitis NANB-1 in sensitive animals are inactivated by the addition of an organic solvent, e.g. 37% formalin, and the heat-treatment (60°C for 10hr) to give a hepatitis NANB-1 viral vaccine. Similarly, the hepatitis NANB-2 viral vaccine is obtained. The resultant respective specific antibodies of the hepatitic viruses permit the detection of the new hepatitis NANB-1 and NANB-2 viral antigens capable of infecting and developing the hepatitis non-A and non-B.
COPYRIGHT: (C)1982,JPO&Japio
JP6022181A 1981-04-21 1981-04-21 Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen Granted JPS57175127A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6022181A JPS57175127A (en) 1981-04-21 1981-04-21 Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6022181A JPS57175127A (en) 1981-04-21 1981-04-21 Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen

Publications (2)

Publication Number Publication Date
JPS57175127A true JPS57175127A (en) 1982-10-28
JPH0369892B2 JPH0369892B2 (en) 1991-11-05

Family

ID=13135884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6022181A Granted JPS57175127A (en) 1981-04-21 1981-04-21 Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen

Country Status (1)

Country Link
JP (1) JPS57175127A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US7838006B2 (en) 2000-08-24 2010-11-23 Immunitor Usa Inc. Viral vaccine composition, process and methods of use
US9974847B2 (en) 2000-08-24 2018-05-22 Immunitor USA, Inc. Treatment and prevention of tuberculosis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55122156A (en) * 1979-03-14 1980-09-19 Chemo Sero Therapeut Res Inst C-type hepatitis virus-associated antigen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55122156A (en) * 1979-03-14 1980-09-19 Chemo Sero Therapeut Res Inst C-type hepatitis virus-associated antigen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US7838006B2 (en) 2000-08-24 2010-11-23 Immunitor Usa Inc. Viral vaccine composition, process and methods of use
US9974847B2 (en) 2000-08-24 2018-05-22 Immunitor USA, Inc. Treatment and prevention of tuberculosis

Also Published As

Publication number Publication date
JPH0369892B2 (en) 1991-11-05

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