Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co LtdfiledCriticalKyowa Hakko Kogyo Co Ltd
Priority to JP2675179ApriorityCriticalpatent/JPS55120586A/en
Publication of JPS55120586ApublicationCriticalpatent/JPS55120586A/en
Publication of JPS6136756B2publicationCriticalpatent/JPS6136756B2/ja
USE: Synthetic intermediate of antitumor agents, mitomycins.
PROCESS: The objective compound I is prepared by reacting a compound II with a sulfonylation agent (e.g. p-toluenesulfonic acid chloride, methanesulfonic acid chloride, etc.) in an inert solvent (e.g. anhydrous ethyl ether, THF, etc.) in the presence of a base (e.g. sodium carbonate, pyridine, etc.) at -78W+30°C.
COPYRIGHT: (C)1980,JPO&Japio
JP2675179A1979-03-091979-03-09Novel mitomycins and their preparation
GrantedJPS55120586A
(en)