JPS55120584A - Manufacture of carboxylic acid derivative - Google Patents

Manufacture of carboxylic acid derivative

Info

Publication number
JPS55120584A
JPS55120584A JP737880A JP737880A JPS55120584A JP S55120584 A JPS55120584 A JP S55120584A JP 737880 A JP737880 A JP 737880A JP 737880 A JP737880 A JP 737880A JP S55120584 A JPS55120584 A JP S55120584A
Authority
JP
Japan
Prior art keywords
manufacture
carboxylic acid
acid derivative
derivative
carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP737880A
Other languages
English (en)
Other versions
JPS564556B2 (ja
Inventor
Marii Kuraidaa Yuunisu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of JPS55120584A publication Critical patent/JPS55120584A/ja
Publication of JPS564556B2 publication Critical patent/JPS564556B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP737880A 1970-12-16 1980-01-24 Manufacture of carboxylic acid derivative Granted JPS55120584A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5739071A GB1356118A (en) 1970-12-16 1970-12-16 1-3-cyano-3,3-diphenylpropyl-4-phenylpiperidine-4-carboxylic acid derivatives
GB5968670A GB1356117A (en) 1970-12-16 1970-12-16 1-3-cyano-3,3-diphenylpropyl-4-phenylpiperidine-4-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
JPS55120584A true JPS55120584A (en) 1980-09-17
JPS564556B2 JPS564556B2 (ja) 1981-01-30

Family

ID=26267682

Family Applications (2)

Application Number Title Priority Date Filing Date
JP737880A Granted JPS55120584A (en) 1970-12-16 1980-01-24 Manufacture of carboxylic acid derivative
JP737980A Granted JPS55127388A (en) 1970-12-16 1980-01-24 Manufacture of carboxylic acid derivative

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP737980A Granted JPS55127388A (en) 1970-12-16 1980-01-24 Manufacture of carboxylic acid derivative

Country Status (11)

Country Link
US (2) US3847923A (ja)
JP (2) JPS55120584A (ja)
AU (2) AU468832B2 (ja)
BE (2) BE776644A (ja)
CA (1) CA947296A (ja)
CH (4) CH572922A5 (ja)
DE (2) DE2161827A1 (ja)
FR (2) FR2118061B1 (ja)
GB (2) GB1356118A (ja)
MY (1) MY7800052A (ja)
NL (2) NL7117061A (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959275A (en) * 1970-12-16 1976-05-25 G. D. Searle & Co. Fused ring N-[1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carbonyloxy]imides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles
US3996214A (en) * 1976-02-23 1976-12-07 G. D. Searle & Co. 5-(1,1-Diphenyl-4-(cyclic amino) but-2-trans-en-1-yl)-2-alkyl-1,3,4-oxadiazoles and intermediates thereto
US4824853A (en) * 1985-10-11 1989-04-25 Janssen Pharmaceutica N.V. α,α-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide, N-oxides and method of treating diarrhea
JP2627278B2 (ja) * 1987-10-20 1997-07-02 三洋電機株式会社 電動式床用吸込具
CA2150951A1 (en) * 1992-12-14 1994-06-23 Angus Murray Macleod 4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperidines as tachykinin receptor antagonists
ATE453621T1 (de) * 2002-07-03 2010-01-15 Glaxo Group Ltd Substituierte 4-phenylpiperidinamide als tachykininantagonisten und serotoninwiederaufnahmehemmer
GB0310724D0 (en) * 2003-05-09 2003-06-11 Glaxo Group Ltd Chemical compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539579A (en) * 1967-11-22 1970-11-10 Janssen Pharm 1 - (3 - cyano - 3,3 - diphenyl - propyl) - 4- phenyl - piperidine - 4 - carboxylic acid esters

Also Published As

Publication number Publication date
JPS55127388A (en) 1980-10-02
DE2161827A1 (de) 1972-07-06
CH572920A5 (ja) 1976-02-27
CA947296A (en) 1974-05-14
FR2118061A1 (ja) 1972-07-28
US3847923A (en) 1974-11-12
AU3678471A (en) 1973-06-14
BE776644A (fr) 1972-06-13
DE2161865A1 (de) 1972-07-06
MY7800052A (en) 1978-12-31
NL7117062A (ja) 1972-06-20
GB1356117A (en) 1974-06-12
AU3678371A (en) 1973-06-14
JPS566429B2 (ja) 1981-02-10
FR2118061B1 (ja) 1975-10-10
JPS564556B2 (ja) 1981-01-30
FR2118060B1 (ja) 1975-10-31
CH572037A5 (ja) 1976-01-30
FR2118060A1 (ja) 1972-07-28
AU468832B2 (en) 1976-01-22
NL7117061A (ja) 1972-06-20
BE776645A (fr) 1972-06-13
CH572923A5 (ja) 1976-02-27
AU472024B2 (en) 1976-05-13
CH572922A5 (ja) 1976-02-27
GB1356118A (en) 1974-06-12
US3843646A (en) 1974-10-22

Similar Documents

Publication Publication Date Title
JPS55162766A (en) Manufacture of 55thenoylpyrroleeacetic acid derivative
CS194176B2 (en) Method of producing derivatives of 7-acylaminocephalosporanic acid
IL37019A (en) Dihydro-furo-quinoline carboxylic acid derivatives
JPS55127388A (en) Manufacture of carboxylic acid derivative
YU36018B (en) Process for obtaining esters of 3-methyl-flavone-8-carboxylic acid
JPS5217490A (en) Production of 66aminopenicillanic acid sulpaoxidosilylesters
ZA717133B (en) Esters of mandeloylaminocephalosporanic acids
CA929535A (en) Manufacture of levulinic acid
JPS5498760A (en) Manufacture of thienyllfatty acid derivative
SE392611B (sv) Forfarande for framstellning av antrakinonkarboxylsyra
JPS537674A (en) Production of xantone carboxylic acid derivatives
JPS54145644A (en) Manufacture of novel mmbenzoylphenylacetic acid
IL39481A0 (en) Derivatives of 9-oxo-13-trans-prostenoic acid esters
ZA717006B (en) Production of methacrolein
AU462548B2 (en) Tetrahydropyridylmethyl carboxylic acid esters
JPS532469A (en) Production of di substituted xantone carboxylic acid compound
ZA713295B (en) New derivatives of mercapto carboxylic acids
AU3741071A (en) Esters of 2,2-diaryl-cyclopropane-carboxylic acids
EG10332A (en) Herbicides of thiolcarbamic acid esters
CA831507A (en) Production of carboxylic acid derivatives
CA833573A (en) Production of carboxylic acid derivatives
CA833574A (en) Production of carboxylic acid derivatives
JPS5625171A (en) Manufacture of phenylacetic acid derivative
IL38340A0 (en) Process for the manufacture of 2-chloroethane-phosphonic acid
CA859776A (en) Production of carboxylic acids