BE776645A - Nouveaux derives d'acides n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarboxyliques-4, utiles notamment comme agents antidiarrheiques, et leur procede de preparation - Google Patents
Nouveaux derives d'acides n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarboxyliques-4, utiles notamment comme agents antidiarrheiques, et leur procede de preparationInfo
- Publication number
- BE776645A BE776645A BE776645A BE776645A BE776645A BE 776645 A BE776645 A BE 776645A BE 776645 A BE776645 A BE 776645A BE 776645 A BE776645 A BE 776645A BE 776645 A BE776645 A BE 776645A
- Authority
- BE
- Belgium
- Prior art keywords
- diphenyl
- cyano
- propyl
- phenyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5968670A GB1356117A (en) | 1970-12-16 | 1970-12-16 | 1-3-cyano-3,3-diphenylpropyl-4-phenylpiperidine-4-carboxylic acid derivatives |
GB5739071A GB1356118A (en) | 1970-12-16 | 1970-12-16 | 1-3-cyano-3,3-diphenylpropyl-4-phenylpiperidine-4-carboxylic acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BE776645A true BE776645A (fr) | 1972-06-13 |
Family
ID=26267682
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE776644A BE776644A (fr) | 1970-12-16 | 1971-12-13 | Nouveaux n-(-n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarbonyloxy-4 amides utiles notamment comme agents antidiarrheiques et leur procede de preparation |
BE776645A BE776645A (fr) | 1970-12-16 | 1971-12-13 | Nouveaux derives d'acides n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarboxyliques-4, utiles notamment comme agents antidiarrheiques, et leur procede de preparation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE776644A BE776644A (fr) | 1970-12-16 | 1971-12-13 | Nouveaux n-(-n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarbonyloxy-4 amides utiles notamment comme agents antidiarrheiques et leur procede de preparation |
Country Status (11)
Country | Link |
---|---|
US (2) | US3847923A (xx) |
JP (2) | JPS55127388A (xx) |
AU (2) | AU468832B2 (xx) |
BE (2) | BE776644A (xx) |
CA (1) | CA947296A (xx) |
CH (4) | CH572920A5 (xx) |
DE (2) | DE2161865A1 (xx) |
FR (2) | FR2118060B1 (xx) |
GB (2) | GB1356118A (xx) |
MY (1) | MY7800052A (xx) |
NL (2) | NL7117061A (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3959275A (en) * | 1970-12-16 | 1976-05-25 | G. D. Searle & Co. | Fused ring N-[1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carbonyloxy]imides |
US4002618A (en) * | 1976-02-23 | 1977-01-11 | G. D. Searle & Co. | 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles |
US3996214A (en) * | 1976-02-23 | 1976-12-07 | G. D. Searle & Co. | 5-(1,1-Diphenyl-4-(cyclic amino) but-2-trans-en-1-yl)-2-alkyl-1,3,4-oxadiazoles and intermediates thereto |
US4824853A (en) * | 1985-10-11 | 1989-04-25 | Janssen Pharmaceutica N.V. | α,α-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide, N-oxides and method of treating diarrhea |
JP2627278B2 (ja) * | 1987-10-20 | 1997-07-02 | 三洋電機株式会社 | 電動式床用吸込具 |
EP0673367A1 (en) * | 1992-12-14 | 1995-09-27 | MERCK SHARP & DOHME LTD. | 4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperidines as tachykinin receptor antagonists |
US20060128752A1 (en) * | 2002-07-03 | 2006-06-15 | Giuseppe Alvaro | Chemical compounds |
GB0310724D0 (en) * | 2003-05-09 | 2003-06-11 | Glaxo Group Ltd | Chemical compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3539579A (en) * | 1967-11-22 | 1970-11-10 | Janssen Pharm | 1 - (3 - cyano - 3,3 - diphenyl - propyl) - 4- phenyl - piperidine - 4 - carboxylic acid esters |
-
1970
- 1970-12-16 GB GB5739071A patent/GB1356118A/en not_active Expired
- 1970-12-16 GB GB5968670A patent/GB1356117A/en not_active Expired
-
1971
- 1971-12-09 CA CA129748A patent/CA947296A/en not_active Expired
- 1971-12-13 CH CH1817371A patent/CH572920A5/xx not_active IP Right Cessation
- 1971-12-13 NL NL7117061A patent/NL7117061A/xx not_active Application Discontinuation
- 1971-12-13 NL NL7117062A patent/NL7117062A/xx not_active Application Discontinuation
- 1971-12-13 FR FR7144705A patent/FR2118060B1/fr not_active Expired
- 1971-12-13 AU AU36784/71A patent/AU468832B2/en not_active Expired
- 1971-12-13 BE BE776644A patent/BE776644A/xx unknown
- 1971-12-13 DE DE19712161865 patent/DE2161865A1/de not_active Ceased
- 1971-12-13 BE BE776645A patent/BE776645A/xx unknown
- 1971-12-13 AU AU36783/71A patent/AU472024B2/en not_active Expired
- 1971-12-13 DE DE19712161827 patent/DE2161827A1/de active Pending
- 1971-12-13 CH CH1817471A patent/CH572037A5/xx not_active IP Right Cessation
- 1971-12-13 FR FR7144706A patent/FR2118061B1/fr not_active Expired
- 1971-12-13 CH CH1694774A patent/CH572923A5/xx not_active IP Right Cessation
- 1971-12-13 CH CH1694674A patent/CH572922A5/xx not_active IP Right Cessation
- 1971-12-15 US US00208442A patent/US3847923A/en not_active Expired - Lifetime
- 1971-12-15 US US00208445A patent/US3843646A/en not_active Expired - Lifetime
-
1978
- 1978-12-31 MY MY197852A patent/MY7800052A/xx unknown
-
1980
- 1980-01-24 JP JP737980A patent/JPS55127388A/ja active Granted
- 1980-01-24 JP JP737880A patent/JPS55120584A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
CH572923A5 (xx) | 1976-02-27 |
DE2161827A1 (de) | 1972-07-06 |
GB1356118A (en) | 1974-06-12 |
JPS566429B2 (xx) | 1981-02-10 |
JPS55120584A (en) | 1980-09-17 |
MY7800052A (en) | 1978-12-31 |
FR2118061B1 (xx) | 1975-10-10 |
CA947296A (en) | 1974-05-14 |
AU3678471A (en) | 1973-06-14 |
AU3678371A (en) | 1973-06-14 |
BE776644A (fr) | 1972-06-13 |
AU468832B2 (en) | 1976-01-22 |
AU472024B2 (en) | 1976-05-13 |
DE2161865A1 (de) | 1972-07-06 |
JPS564556B2 (xx) | 1981-01-30 |
US3843646A (en) | 1974-10-22 |
NL7117062A (xx) | 1972-06-20 |
FR2118061A1 (xx) | 1972-07-28 |
JPS55127388A (en) | 1980-10-02 |
CH572922A5 (xx) | 1976-02-27 |
CH572037A5 (xx) | 1976-01-30 |
NL7117061A (xx) | 1972-06-20 |
FR2118060A1 (xx) | 1972-07-28 |
GB1356117A (en) | 1974-06-12 |
FR2118060B1 (xx) | 1975-10-31 |
US3847923A (en) | 1974-11-12 |
CH572920A5 (xx) | 1976-02-27 |
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