JPS55118469A - Thioamide derivative - Google Patents
Thioamide derivativeInfo
- Publication number
- JPS55118469A JPS55118469A JP3485079A JP3485079A JPS55118469A JP S55118469 A JPS55118469 A JP S55118469A JP 3485079 A JP3485079 A JP 3485079A JP 3485079 A JP3485079 A JP 3485079A JP S55118469 A JPS55118469 A JP S55118469A
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- compound
- peptic
- derivative
- bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A thioamide derivative of formula I (R1 is H, phenyl, thienyl or naphthyl; R2,3 are H or R1 and R2 or R2 and R3 may together form a ring; A is alkylene; excluding a compound wherein R1 is phenyl, R2,3 are H, A is ethylene, and the bond between 4- and 5-positions is double bond).
EXAMPLE: 6-Phenyl-2-thiocarbamoylmethyl-3(2H)-pyridazinone.
USE: Remedy and preventive for peptic ulcer. Long sustaining activity, low toxicity and high heat-resistance. Also effective to peptic hyperacidity and duodenal ulcer.
PROCESS: The compound I can be prepared by dissolving a nitrile derivative II in a proper inert organic solvent such as an alcohol, acetone, etc., and introducing H2S gas to the solution at room temperature pref. in the presence of a basic catalyst such as piperazine or propylamine.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3485079A JPS55118469A (en) | 1979-03-02 | 1979-03-02 | Thioamide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3485079A JPS55118469A (en) | 1979-03-02 | 1979-03-02 | Thioamide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55118469A true JPS55118469A (en) | 1980-09-11 |
JPS638940B2 JPS638940B2 (en) | 1988-02-25 |
Family
ID=12425649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3485079A Granted JPS55118469A (en) | 1979-03-02 | 1979-03-02 | Thioamide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55118469A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4496564A (en) * | 1981-03-09 | 1985-01-29 | Ici Americas Inc. | Amide derivatives |
WO1986001506A1 (en) * | 1984-08-28 | 1986-03-13 | Yoshitomi Pharmaceutical Industries, Ltd. | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM |
-
1979
- 1979-03-02 JP JP3485079A patent/JPS55118469A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4496564A (en) * | 1981-03-09 | 1985-01-29 | Ici Americas Inc. | Amide derivatives |
WO1986001506A1 (en) * | 1984-08-28 | 1986-03-13 | Yoshitomi Pharmaceutical Industries, Ltd. | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM |
Also Published As
Publication number | Publication date |
---|---|
JPS638940B2 (en) | 1988-02-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS55118469A (en) | Thioamide derivative | |
JPS5293470A (en) | Gelatin curing agent | |
GB1339389A (en) | Pyrimidin-6yl acethydroxamic acids their method of preparation and their therepeutic application | |
JPS55118468A (en) | Thioamide derivative | |
JPS5473710A (en) | Production of 2-butene-1,4-diol derivative | |
GB1463258A (en) | Process for the preparation of 1,2-fused five-membered or six- membered 1,3-dinitrogen-heterocyclic compounds and their use | |
JPS565462A (en) | Piperazinylalkoxyindanes and their acid addition salt | |
JPS5764683A (en) | 2-(substituted phenyl)-5-alkylthiazolidin-4-one and remedy for pepticulcer containing said compound as active component | |
JPS55118470A (en) | Thiourea derivative | |
JPS51149277A (en) | Process for preparing new benzotriazole compounds | |
JPS5663961A (en) | Novel isoindoline derivative and its preparation | |
JPS525730A (en) | Process for preparation of 1,3,5-tri-substituted derivatives | |
JPS51125281A (en) | A process for preparing indazole derivatives | |
JPS5285169A (en) | Novel allantoin-n-acetylglutamine-aluminum molecular complex and its p reparation | |
JPS5511503A (en) | Condensed heterocyclic compound | |
JPS52125146A (en) | Arylacetylenesulfonamide derivatives and method of preparing the same | |
GB1352089A (en) | Bis-styryltriazoles their use for the optical brightening of organic materials and processes for their manufacture | |
JPS51125092A (en) | A process for preparing novel substituted s-triazines | |
JPS51136653A (en) | Process for preparing novel organophosphorous compounds | |
JPS51138698A (en) | Process preparing 2-cycloalkylthioadenine s | |
JPS5668666A (en) | Pyrrole derivative | |
JPS51125242A (en) | Process for preparing bis-(benzamido)- benzene derivatives | |
JPS52100462A (en) | Novel lactones and method of making same | |
JPS55151547A (en) | Production of guanidinocapronic ester | |
JPS5772962A (en) | Prparation of substituted acetaldehyde |