JPS55111419A - Antitumorigenic agent - Google Patents

Antitumorigenic agent

Info

Publication number
JPS55111419A
JPS55111419A JP1786979A JP1786979A JPS55111419A JP S55111419 A JPS55111419 A JP S55111419A JP 1786979 A JP1786979 A JP 1786979A JP 1786979 A JP1786979 A JP 1786979A JP S55111419 A JPS55111419 A JP S55111419A
Authority
JP
Japan
Prior art keywords
formula
agent
geldanamycin
effective component
antitumorigenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1786979A
Other languages
Japanese (ja)
Other versions
JPS6341885B2 (en
Inventor
Kazuya Sasaki
Yukio Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP1786979A priority Critical patent/JPS55111419A/en
Publication of JPS55111419A publication Critical patent/JPS55111419A/en
Publication of JPS6341885B2 publication Critical patent/JPS6341885B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: An antitumorigenic agent that contains a geldanamycin derivative as an effective component.
CONSTITUTION: Said agent contains a geldanamycin derivative of formula I (R is amino, methylamino, dimethylamino) as an effective component. It shows great activity of inhibiting the growth of experimental tumor cells, W-2K-11. It is administered orally or parenterally. The compound of formula I is obtained by treating geldanamycin of formula II with ammonia, methylamine or dimethylamine.
COPYRIGHT: (C)1980,JPO&Japio
JP1786979A 1979-02-20 1979-02-20 Antitumorigenic agent Granted JPS55111419A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1786979A JPS55111419A (en) 1979-02-20 1979-02-20 Antitumorigenic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1786979A JPS55111419A (en) 1979-02-20 1979-02-20 Antitumorigenic agent

Publications (2)

Publication Number Publication Date
JPS55111419A true JPS55111419A (en) 1980-08-28
JPS6341885B2 JPS6341885B2 (en) 1988-08-19

Family

ID=11955670

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1786979A Granted JPS55111419A (en) 1979-02-20 1979-02-20 Antitumorigenic agent

Country Status (1)

Country Link
JP (1) JPS55111419A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872715B2 (en) 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
US6890917B2 (en) 2001-03-30 2005-05-10 The United States Of America As Represented By The Department Of Health And Human Services Geldanamycin derivative and method of treating cancer using same
US7259156B2 (en) 2004-05-20 2007-08-21 Kosan Biosciences Incorporated Geldanamycin compounds and method of use
EP1420747A4 (en) * 2001-08-06 2010-06-02 Kosan Biosciences Inc Benzoquinone ansamycins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55111469A (en) * 1979-02-19 1980-08-28 Kaken Pharmaceut Co Ltd Novel geldanamycin derivative, its preparation, and antitumor drug comprising it as active ingredient

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55111469A (en) * 1979-02-19 1980-08-28 Kaken Pharmaceut Co Ltd Novel geldanamycin derivative, its preparation, and antitumor drug comprising it as active ingredient

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890917B2 (en) 2001-03-30 2005-05-10 The United States Of America As Represented By The Department Of Health And Human Services Geldanamycin derivative and method of treating cancer using same
US6872715B2 (en) 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
US7405208B2 (en) 2001-08-06 2008-07-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
EP1420747A4 (en) * 2001-08-06 2010-06-02 Kosan Biosciences Inc Benzoquinone ansamycins
US7259156B2 (en) 2004-05-20 2007-08-21 Kosan Biosciences Incorporated Geldanamycin compounds and method of use
US7378407B2 (en) 2004-05-20 2008-05-27 Kosan Biosciences Incorporated Geldanamycin compounds and method of use

Also Published As

Publication number Publication date
JPS6341885B2 (en) 1988-08-19

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