JPS55106264A - Manufacture of benzimidazolylbenzofurans - Google Patents
Manufacture of benzimidazolylbenzofuransInfo
- Publication number
- JPS55106264A JPS55106264A JP1257680A JP1257680A JPS55106264A JP S55106264 A JPS55106264 A JP S55106264A JP 1257680 A JP1257680 A JP 1257680A JP 1257680 A JP1257680 A JP 1257680A JP S55106264 A JPS55106264 A JP S55106264A
- Authority
- JP
- Japan
- Prior art keywords
- benzimidazolylbenzofurans
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792904829 DE2904829A1 (de) | 1979-02-08 | 1979-02-08 | Verfahren zur herstellung von benzimidazolylbenzofuran |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55106264A true JPS55106264A (en) | 1980-08-14 |
Family
ID=6062480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1257680A Pending JPS55106264A (en) | 1979-02-08 | 1980-02-06 | Manufacture of benzimidazolylbenzofurans |
Country Status (5)
Country | Link |
---|---|
US (1) | US4268670A (ja) |
EP (1) | EP0014411B1 (ja) |
JP (1) | JPS55106264A (ja) |
BR (1) | BR8000748A (ja) |
DE (2) | DE2904829A1 (ja) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364944A (en) * | 1989-10-27 | 1994-11-15 | American Home Products Corporation | Substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid compounds |
US6048927A (en) * | 1999-03-01 | 2000-04-11 | Dow Corning Corporation | Method for forming fiber treating composition comprising an amide-functional polyorganosiloxane and an alkylsulfate of benzimidazole |
DE20002868U1 (de) | 2000-02-17 | 2000-05-04 | Frenger Systemen Bv Heiz Und K | Strahlflächenaufbau |
US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
US7098231B2 (en) | 2003-01-22 | 2006-08-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
US7582770B2 (en) | 2004-02-20 | 2009-09-01 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
EP1915378A4 (en) | 2005-08-12 | 2009-07-22 | Boehringer Ingelheim Int | VIRUS POLYMERASE INHIBITORS |
ES2790358T3 (es) | 2011-12-28 | 2020-10-27 | Global Blood Therapeutics Inc | Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular |
PT2797416T (pt) | 2011-12-28 | 2017-10-23 | Global Blood Therapeutics Inc | Compostos de benzaldeído substituído e métodos para a sua utilização no aumento da oxigenação de tecidos |
US10100043B2 (en) | 2013-03-15 | 2018-10-16 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
AP2015008718A0 (en) | 2013-03-15 | 2015-09-30 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
CN105073728A (zh) | 2013-03-15 | 2015-11-18 | 全球血液疗法股份有限公司 | 化合物及其用于调节血红蛋白的用途 |
US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
MY180206A (en) | 2013-03-15 | 2020-11-25 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
DK3102208T3 (da) | 2014-02-07 | 2021-03-08 | Global Blood Therapeutics Inc | Krystallinsk polymorf af den frie base af 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyd |
MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
MA43373A (fr) | 2015-12-04 | 2018-10-10 | Global Blood Therapeutics Inc | Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde |
AR108435A1 (es) | 2016-05-12 | 2018-08-22 | Global Blood Therapeutics Inc | Proceso para sintetizar 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)-piridin-3-il)metoxi)benzaldehído |
TWI778983B (zh) | 2016-10-12 | 2022-10-01 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
WO2020072377A1 (en) | 2018-10-01 | 2020-04-09 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin for the treatment of sickle cell disease |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3940417A (en) * | 1970-12-09 | 1976-02-24 | Ciba-Geigy Corporation | Quaternised benzofuranyl-benzimidazoles |
BE787580A (fr) * | 1971-08-13 | 1973-02-14 | Hoechst Ag | Procede de preparation de derives du furanne |
DE2304265A1 (de) * | 1973-01-30 | 1974-08-01 | Basf Ag | 6-triazolyl-(2')-benzofurane und optische aufheller |
CH632628B (de) * | 1976-07-26 | Ciba Geigy Ag | Verfahren zur herstellung von benzofuranyl-benzimidazolen und deren verwendung als optische aufheller. | |
US4143055A (en) * | 1978-03-27 | 1979-03-06 | Gruppo Lepetit S.P.A. | 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives |
EP0010063B1 (de) * | 1978-10-04 | 1982-12-29 | Ciba-Geigy Ag | Verfahren zur Herstellung von Furanyl-benzazolen |
-
1979
- 1979-02-08 DE DE19792904829 patent/DE2904829A1/de not_active Withdrawn
-
1980
- 1980-01-21 US US06/113,933 patent/US4268670A/en not_active Expired - Lifetime
- 1980-01-28 EP EP80100429A patent/EP0014411B1/de not_active Expired
- 1980-01-28 DE DE8080100429T patent/DE3060027D1/de not_active Expired
- 1980-02-06 JP JP1257680A patent/JPS55106264A/ja active Pending
- 1980-02-07 BR BR8000748A patent/BR8000748A/pt unknown
Also Published As
Publication number | Publication date |
---|---|
EP0014411B1 (de) | 1981-10-07 |
DE2904829A1 (de) | 1980-08-14 |
BR8000748A (pt) | 1980-10-21 |
EP0014411A1 (de) | 1980-08-20 |
US4268670A (en) | 1981-05-19 |
DE3060027D1 (en) | 1981-12-17 |
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