JPS5495591A - Somatostatin analogue - Google Patents

Somatostatin analogue

Info

Publication number
JPS5495591A
JPS5495591A JP14796578A JP14796578A JPS5495591A JP S5495591 A JPS5495591 A JP S5495591A JP 14796578 A JP14796578 A JP 14796578A JP 14796578 A JP14796578 A JP 14796578A JP S5495591 A JPS5495591 A JP S5495591A
Authority
JP
Japan
Prior art keywords
somatostatin analogue
somatostatin
analogue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14796578A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6241240B2 (enExample
Inventor
Efu Bueebaa Danieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5495591A publication Critical patent/JPS5495591A/ja
Publication of JPS6241240B2 publication Critical patent/JPS6241240B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP14796578A 1977-12-01 1978-12-01 Somatostatin analogue Granted JPS5495591A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/856,364 US4139526A (en) 1977-12-01 1977-12-01 Somatostatin analogs

Publications (2)

Publication Number Publication Date
JPS5495591A true JPS5495591A (en) 1979-07-28
JPS6241240B2 JPS6241240B2 (enExample) 1987-09-02

Family

ID=25323425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14796578A Granted JPS5495591A (en) 1977-12-01 1978-12-01 Somatostatin analogue

Country Status (7)

Country Link
US (1) US4139526A (enExample)
EP (1) EP0002262B1 (enExample)
JP (1) JPS5495591A (enExample)
DE (1) DE2862319D1 (enExample)
DK (1) DK539478A (enExample)
IE (1) IE47683B1 (enExample)
IT (1) IT1158152B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59110662A (ja) * 1982-12-06 1984-06-26 メルク　エンド　カムパニー　インコーポレーテッド 架橋環状ヘキサペプチドソマトスタチン類縁体
JP2006505507A (ja) * 2002-07-17 2006-02-16 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 二環式オリゴペプチド及びグルカゴン受容体アンタゴニストとしてのその使用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191754A (en) * 1979-02-28 1980-03-04 Merck & Co., Inc. Bicyclic somatostatin analogs
US4190648A (en) * 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
DE19375086I2 (de) * 1979-11-27 2003-01-09 Novartis Ag Polypeptide Verfahren zu ihrer Herstellung pharmazeutische Zusammensetzungen die diese Polypeptide enthalten und ihre Verwendung
US4663435A (en) * 1982-12-06 1987-05-05 Merck & Co., Inc. Bridged cyclic hexapeptide somatostatin analogs
DE3910667A1 (de) * 1988-04-11 1989-10-19 Sandoz Ag Peptidderivate
US7101848B2 (en) * 2002-10-08 2006-09-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Bicyclic oligopeptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2416048A1 (de) * 1974-04-03 1975-10-30 Hoechst Ag Neue peptide mit biologischer wirkung
DE2460469A1 (de) * 1974-12-20 1976-07-01 Hoechst Ag Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung
NL7607987A (nl) * 1975-08-08 1977-02-10 Merck & Co Inc Werkwijze voor het bereiden van peptiden.
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor
US3997517A (en) * 1976-01-30 1976-12-14 American Home Products Corporation Cyclic somatostatin disulfide analogues

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59110662A (ja) * 1982-12-06 1984-06-26 メルク　エンド　カムパニー　インコーポレーテッド 架橋環状ヘキサペプチドソマトスタチン類縁体
JP2006505507A (ja) * 2002-07-17 2006-02-16 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 二環式オリゴペプチド及びグルカゴン受容体アンタゴニストとしてのその使用

Also Published As

Publication number Publication date
US4139526A (en) 1979-02-13
IT7852161A0 (it) 1978-12-01
DK539478A (da) 1979-06-02
IE47683B1 (en) 1984-05-30
IT1158152B (it) 1987-02-18
EP0002262B1 (en) 1983-09-14
EP0002262A1 (en) 1979-06-13
JPS6241240B2 (enExample) 1987-09-02
IE782372L (en) 1979-06-01
DE2862319D1 (en) 1983-10-20

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