IT7852161A0 - Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto - Google Patents
Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenutoInfo
- Publication number
- IT7852161A0 IT7852161A0 IT7852161A IT5216178A IT7852161A0 IT 7852161 A0 IT7852161 A0 IT 7852161A0 IT 7852161 A IT7852161 A IT 7852161A IT 5216178 A IT5216178 A IT 5216178A IT 7852161 A0 IT7852161 A0 IT 7852161A0
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- product obtained
- somatostatin analogues
- somatostatin
- Prior art date
Links
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
- 229940075620 somatostatin analogue Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/856,364 US4139526A (en) | 1977-12-01 | 1977-12-01 | Somatostatin analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7852161A0 true IT7852161A0 (it) | 1978-12-01 |
| IT1158152B IT1158152B (it) | 1987-02-18 |
Family
ID=25323425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT52161/78A IT1158152B (it) | 1977-12-01 | 1978-12-01 | Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4139526A (it) |
| EP (1) | EP0002262B1 (it) |
| JP (1) | JPS5495591A (it) |
| DE (1) | DE2862319D1 (it) |
| DK (1) | DK539478A (it) |
| IE (1) | IE47683B1 (it) |
| IT (1) | IT1158152B (it) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4191754A (en) * | 1979-02-28 | 1980-03-04 | Merck & Co., Inc. | Bicyclic somatostatin analogs |
| US4190648A (en) * | 1979-03-13 | 1980-02-26 | Merck & Co., Inc. | Peptides having somatostatin activity |
| ATE2512T1 (de) * | 1979-11-27 | 1983-03-15 | Sandoz Ag | Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung. |
| US4663435A (en) * | 1982-12-06 | 1987-05-05 | Merck & Co., Inc. | Bridged cyclic hexapeptide somatostatin analogs |
| DE3379657D1 (en) * | 1982-12-06 | 1989-05-24 | Merck & Co Inc | Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them |
| DE3910667A1 (de) * | 1988-04-11 | 1989-10-19 | Sandoz Ag | Peptidderivate |
| WO2004007524A2 (en) * | 2002-07-17 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Bicyclic oligopeptides |
| US7101848B2 (en) * | 2002-10-08 | 2006-09-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Bicyclic oligopeptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2416048A1 (de) * | 1974-04-03 | 1975-10-30 | Hoechst Ag | Neue peptide mit biologischer wirkung |
| DE2460469A1 (de) * | 1974-12-20 | 1976-07-01 | Hoechst Ag | Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung |
| NL7607987A (nl) * | 1975-08-08 | 1977-02-10 | Merck & Co Inc | Werkwijze voor het bereiden van peptiden. |
| CA1083143A (en) * | 1976-01-02 | 1980-08-05 | Nedumparambil A. Abraham | Carba derivatives of somatostatin and process therefor |
| US3997517A (en) * | 1976-01-30 | 1976-12-14 | American Home Products Corporation | Cyclic somatostatin disulfide analogues |
-
1977
- 1977-12-01 US US05/856,364 patent/US4139526A/en not_active Expired - Lifetime
-
1978
- 1978-11-30 DK DK539478A patent/DK539478A/da unknown
- 1978-11-30 IE IE2372/78A patent/IE47683B1/en unknown
- 1978-12-01 IT IT52161/78A patent/IT1158152B/it active
- 1978-12-01 EP EP78101494A patent/EP0002262B1/en not_active Expired
- 1978-12-01 DE DE7878101494T patent/DE2862319D1/de not_active Expired
- 1978-12-01 JP JP14796578A patent/JPS5495591A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IE47683B1 (en) | 1984-05-30 |
| DE2862319D1 (en) | 1983-10-20 |
| DK539478A (da) | 1979-06-02 |
| EP0002262A1 (en) | 1979-06-13 |
| JPS6241240B2 (it) | 1987-09-02 |
| IT1158152B (it) | 1987-02-18 |
| JPS5495591A (en) | 1979-07-28 |
| EP0002262B1 (en) | 1983-09-14 |
| US4139526A (en) | 1979-02-13 |
| IE782372L (en) | 1979-06-01 |
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