JPS5419913A - Alphaahalomethyl derivative of alphaaamino acid - Google Patents

Alphaahalomethyl derivative of alphaaamino acid

Info

Publication number
JPS5419913A
JPS5419913A JP8361978A JP8361978A JPS5419913A JP S5419913 A JPS5419913 A JP S5419913A JP 8361978 A JP8361978 A JP 8361978A JP 8361978 A JP8361978 A JP 8361978A JP S5419913 A JPS5419913 A JP S5419913A
Authority
JP
Japan
Prior art keywords
alphaahalomethyl
alphaaamino
derivative
acid
alphaahalomethyl derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8361978A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0122259B2 (OSRAM
Inventor
Bei Fuiritsupe
Yunku Mishieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of JPS5419913A publication Critical patent/JPS5419913A/ja
Publication of JPH0122259B2 publication Critical patent/JPH0122259B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
JP8361978A 1977-07-11 1978-07-11 Alphaahalomethyl derivative of alphaaamino acid Granted JPS5419913A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81476577A 1977-07-11 1977-07-11
US2875779A 1979-04-10 1979-04-10
US2875879A 1979-04-10 1979-04-10

Publications (2)

Publication Number Publication Date
JPS5419913A true JPS5419913A (en) 1979-02-15
JPH0122259B2 JPH0122259B2 (OSRAM) 1989-04-25

Family

ID=27363337

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8361978A Granted JPS5419913A (en) 1977-07-11 1978-07-11 Alphaahalomethyl derivative of alphaaamino acid

Country Status (9)

Country Link
JP (1) JPS5419913A (OSRAM)
AU (1) AU522660B2 (OSRAM)
BE (3) BE868882A (OSRAM)
CA (1) CA1091661A (OSRAM)
CH (1) CH642055A5 (OSRAM)
DE (1) DE2828739A1 (OSRAM)
FR (1) FR2430418A1 (OSRAM)
GB (1) GB2001960B (OSRAM)
NL (2) NL190662C (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5791958A (en) * 1980-08-23 1982-06-08 Merrell Toraude & Co Fluorinated pentene diamine derivative

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16634A (en) * 1980-06-16 1983-12-05 Merrell Dow Pharma Method of inhibiting the growth of protozoa
US4399151A (en) 1980-06-16 1983-08-16 Merrell Dow Pharmaceuticals Inc. Method of inhibiting the growth of protozoa
GB2083030B (en) * 1980-08-23 1984-03-07 Merrell Toraude & Co Fluorinated pentene diamine derivatives
US4437873A (en) 1981-03-23 1984-03-20 Merrell Dow Pharmaceuticals Inc. Method of inhibiting algae
US4446151A (en) * 1981-08-19 1984-05-01 Merrell Toraude Et Compagnie Decarboxylase-inhibiting fluorinated pentane diamine derivatives
US4423073A (en) 1981-08-19 1983-12-27 Merrell Toraude Et Compagnie Fluorinated diaminopentene derivatives
US4435425A (en) 1982-04-09 1984-03-06 Merrell Toraude Et Compagnie Fluorinated diaminobutane derivatives
JPS62148462A (ja) * 1985-12-19 1987-07-02 メレルダウフア−マス−テイカルズ　インコ−ポレ−テツド 原生動物の生長を抑制する新規な方法
EP0326766B1 (en) * 1988-02-05 1992-06-17 Merrell Dow Pharmaceuticals Inc. 5-substituted ornithine derivatives
CA1319123C (en) * 1988-08-31 1993-06-15 Andrew T. Au Method for the production of (-) 2-substituted-ornithines
US6103220A (en) * 1998-01-23 2000-08-15 Levine; Martin Lysine decarboxylase inhibitors for the prevention and treatment of periodontal disease
US6187296B1 (en) 1998-01-23 2001-02-13 The Board Of Regents Of The University Of Oklahoma Lysine decarboxylase inhibitors for the prevention and treatment of periodontal disease
US7015349B2 (en) 2003-03-26 2006-03-21 The Gillette Company Reduction of hair growth
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
CN120943886B (zh) * 2025-10-16 2026-01-30 浙江肽昇生物医药有限公司 一种三肽Fmoc-Pro-Pro-Pro-OH的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR64495B (en) * 1977-06-01 1980-03-31 Merck & Co Inc Novel fluorinated amino acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5791958A (en) * 1980-08-23 1982-06-08 Merrell Toraude & Co Fluorinated pentene diamine derivative

Also Published As

Publication number Publication date
NL7807453A (nl) 1979-01-15
NL950027I2 (nl) 1997-06-02
JPH0122259B2 (OSRAM) 1989-04-25
GB2001960A (en) 1979-02-14
CH642055A5 (de) 1984-03-30
NL950027I1 (nl) 1996-02-01
NL190662C (nl) 1994-06-16
AU3732778A (en) 1980-01-03
DE2828739A1 (de) 1979-02-01
BE868882A (fr) 1978-11-03
AU522660B2 (en) 1982-06-17
NL190662B (nl) 1994-01-17
FR2430418A1 (fr) 1980-02-01
CA1091661A (en) 1980-12-16
GB2001960B (en) 1982-02-24
FR2430418B1 (OSRAM) 1984-07-13
BE881208A (fr) 1980-05-16
BE881209A (fr) 1980-05-16

Similar Documents

Publication Publication Date Title
PH15435A (en) Phthalazin-4-ylacetic acid derivatives
JPS5481274A (en) Manufacture of oosubstituted derivative of ****cyanidanee33ol
NZ184328A (en) Preparation of di-n-propylacetic acid
GB2002762B (en) Cycloalkylidenemethylphenylacetic acid derivatives
JPS53137992A (en) Nnalkyllnnacyl derivative of thienamycine
GB2005264B (en) Haloaminoalkanoic acid derivatives
JPS5414916A (en) Alphaaacetylene derivative of alphaaamino acid
AU3728478A (en) Derivatives of amidinopenicillanic acid
GB1557553A (en) Oxazolinoazetidinylbutyric acid derivatives
GB2002764B (en) Derivatives of n-substituted-2-aminobenzoic acid
GB2075968B (en) Benzylsulphonic acid derivatives
JPS5436262A (en) Alphaahalomethyl derivative of amino acid
AU4057878A (en) Clavulinic acid derivatives
ZA78820B (en) Novel benzoheterocyclylglyoxylic acid derivatives
JPS54119475A (en) Manufacture of 11hydroxyaporphine derivative
JPS5448749A (en) Manufacture of 11aminoo44bromoanthraquinonee22sulfonic acid
JPS5392744A (en) Derivative of omegaaaryloxyy133 prostin acid
GB2003149B (en) Derivatives of oxanilic acid
JPS545987A (en) Production of pyperadine carbodithionic acid derivative
JPS5377044A (en) Derivative of dialkylaminoalkylamido azulenylglyoxylic acid
JPS5466681A (en) Manufacture of 66thiatetracycline derivative
JPS5479258A (en) Manufacture of 22naphthylpropionic acid derivative
JPS5479268A (en) Manufacture of 55nitroo22ten acid
JPS5692861A (en) Carbothio acid derivative of mercaptoacylamino acid
PH14928A (en) 2-methyl-2-phenoxy-propionic acid derivatives

Legal Events

Date Code Title Description
A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 19870901

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 19891024