JPS54154725A - Production of 3-cycloalkenone - Google Patents

Production of 3-cycloalkenone

Info

Publication number
JPS54154725A
JPS54154725A JP6089878A JP6089878A JPS54154725A JP S54154725 A JPS54154725 A JP S54154725A JP 6089878 A JP6089878 A JP 6089878A JP 6089878 A JP6089878 A JP 6089878A JP S54154725 A JPS54154725 A JP S54154725A
Authority
JP
Japan
Prior art keywords
isomerization
catalyst
formula
cycloalkene
effected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6089878A
Other languages
Japanese (ja)
Other versions
JPS6143335B2 (en
Inventor
Ryoji Noyori
Masaaki Suzuki
Seiji Kurozumi
Yoshinobu Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP6089878A priority Critical patent/JPS54154725A/en
Publication of JPS54154725A publication Critical patent/JPS54154725A/en
Publication of JPS6143335B2 publication Critical patent/JPS6143335B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The specific isomerization of 1,2-epoxy-3-cycloalkene is effected in the presence of a catalyst as metal Pd under mild conditions to produce title compound useful as intermediate for drugs, such as prostaglandin, in high yield.
CONSTITUTION: The isomerization of 1,2-epoxy-3-cycloalkene of formula I (Z is 1W4C alkylene forming a ring, where one carbon atoms included in the 5W8 membered ring may be substituted with an organic radical of 1W10 carbon atoms) is effected in the presence of an isomerization catalyst at room temperature in a neutral medium to produce the objective compound of formula II. The isomerization catalyst used is, e.g., preferably metal palladium, palladium chloride. When necessary, the use of organic phosphine as the auxilliary catalyst is preferred. Palldium tetrakistriphenylphosphine complex of formula III (X is halogen; R is monofunctional organic radical; m is 0, 1, 2; 1 is 1W4) also can be employed.
USE: Starting material for agricultural chemicals and perfume.
COPYRIGHT: (C)1979,JPO&Japio
JP6089878A 1978-05-24 1978-05-24 Production of 3-cycloalkenone Granted JPS54154725A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6089878A JPS54154725A (en) 1978-05-24 1978-05-24 Production of 3-cycloalkenone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6089878A JPS54154725A (en) 1978-05-24 1978-05-24 Production of 3-cycloalkenone

Publications (2)

Publication Number Publication Date
JPS54154725A true JPS54154725A (en) 1979-12-06
JPS6143335B2 JPS6143335B2 (en) 1986-09-26

Family

ID=13155627

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6089878A Granted JPS54154725A (en) 1978-05-24 1978-05-24 Production of 3-cycloalkenone

Country Status (1)

Country Link
JP (1) JPS54154725A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0133711A2 (en) * 1983-08-23 1985-03-06 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Isomerization of 1,3,3-trimethyl-7-oxabicyclo-[4.1.0] heptan-2-one

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0133711A2 (en) * 1983-08-23 1985-03-06 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Isomerization of 1,3,3-trimethyl-7-oxabicyclo-[4.1.0] heptan-2-one
JPS6058934A (en) * 1983-08-23 1985-04-05 エフ・ホフマン―ラ　ロシユ　アーゲー Isomerization of epoxide

Also Published As

Publication number Publication date
JPS6143335B2 (en) 1986-09-26

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