JPS54144319A - Novel aminoglucopyranoside derivative its preparation, and oncostatic drugs comprising it as active constituent - Google Patents
Novel aminoglucopyranoside derivative its preparation, and oncostatic drugs comprising it as active constituentInfo
- Publication number
- JPS54144319A JPS54144319A JP5277978A JP5277978A JPS54144319A JP S54144319 A JPS54144319 A JP S54144319A JP 5277978 A JP5277978 A JP 5277978A JP 5277978 A JP5277978 A JP 5277978A JP S54144319 A JPS54144319 A JP S54144319A
- Authority
- JP
- Japan
- Prior art keywords
- oncostatic
- formula
- aminoglucopyranoside
- derivative
- drugs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:An aminoglucopyranoside derivative of formula : (R is H or acetyl group; Y is H or nitroso group).
EXAMPLE: 3-[ 3-( 2-chloroethyl )-3-nitrosoureido ]- 3-deoxy-D-glucopyranose.
USE: Oncostatic drygs, antibacterials or intermediates for medicines and pesticides, having oncostatic activities in mice implanted with L-1210 without decreasing the white blood-corpuscle.
PROCESS: An 3-amino-3-deoxy-D-glucose by formula II is condensed with 2-chloroethyl isocyanate, and, if necessary, the reaction product is nitrasated and/or acetylated to give the compound of formula I. The starting material of formula II can be ex tracted from the cultured substance of bacteria, Bacillus sp. PB-2.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5277978A JPS54144319A (en) | 1978-05-04 | 1978-05-04 | Novel aminoglucopyranoside derivative its preparation, and oncostatic drugs comprising it as active constituent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5277978A JPS54144319A (en) | 1978-05-04 | 1978-05-04 | Novel aminoglucopyranoside derivative its preparation, and oncostatic drugs comprising it as active constituent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54144319A true JPS54144319A (en) | 1979-11-10 |
JPS6310713B2 JPS6310713B2 (en) | 1988-03-08 |
Family
ID=12924331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5277978A Granted JPS54144319A (en) | 1978-05-04 | 1978-05-04 | Novel aminoglucopyranoside derivative its preparation, and oncostatic drugs comprising it as active constituent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54144319A (en) |
-
1978
- 1978-05-04 JP JP5277978A patent/JPS54144319A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6310713B2 (en) | 1988-03-08 |
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