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Asahi Chemical Industry Co Ltd
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Asahi Chemical Industry Co Ltd
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Priority to JP4556578ApriorityCriticalpatent/JPS54138597A/en
Publication of JPS54138597ApublicationCriticalpatent/JPS54138597A/en
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
NEW MATERIAL:A nitrogen-containing macrocyclic compound of formula I (R1 and R2 are H, lower alkyl, phenyl; R3 is lower alkyl; A is straight chain or branched lower alkylene; n is 0,l; m is 1,2).
EXAMPLE: The compound of formula II.
USE: Medicine and its intermediate. The compound has remarkable pharmacological activity, and also useful as an intermediate of a medicine such as macrolide antibiotic substance.
PROCESS: The compound I is prepared by the photo-irradiation of a phthalimide derivative of formula III in the presence of a lower alkanol of formula IV. The photo-irradiation is carried out by the use of a 300W500W high-pressure mercury lamp in an inert gas atmosphere such as nitrogen, argon, etc., for 3W30 hours.
COPYRIGHT: (C)1979,JPO&Japio
JP4556578A1978-04-181978-04-18Nitrogen-containing macrocyclic compound and its preparation
PendingJPS54138597A
(en)