JPS54132585A - Maleimide-substituted carboxylic acid ester - Google Patents

Maleimide-substituted carboxylic acid ester

Info

Publication number
JPS54132585A
JPS54132585A JP4099578A JP4099578A JPS54132585A JP S54132585 A JPS54132585 A JP S54132585A JP 4099578 A JP4099578 A JP 4099578A JP 4099578 A JP4099578 A JP 4099578A JP S54132585 A JPS54132585 A JP S54132585A
Authority
JP
Japan
Prior art keywords
compound
maleimide
carboxylic acid
substituted carboxylic
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4099578A
Other languages
Japanese (ja)
Inventor
Shinsuke Fukuoka
Koichi Yasui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP4099578A priority Critical patent/JPS54132585A/en
Publication of JPS54132585A publication Critical patent/JPS54132585A/en
Pending legal-status Critical Current

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)

Abstract

NEW MATERIAL:A maleimide-substituted carboxylic acid ester of formula I (R is difunctional aliphatic, alicyclic, or araliphatic hydrocarbon residue, difunctional aromaticring-containing residue; Z is 0, sulfone).
EXAMPLE: p-(N-Maleimido)benzoic acid 4-morpholinyl ester.
USE: Efficient bonding reagent of sulfuhydryl-containing compound with an amino- containing compound. Useful for the immobilization of enzyme, enzyme immuno- assay, etc.
PROCESS: The compound I is prepared by reacting a compound II with a compound III in a solvent such as benzene, toluene, etc., in the presence of a dehydrating condensation agent such as carbodiimide, sulfuric acid, etc. The reaction temp. is -15 W +50°C when the condensing agent is carbodiimide, and room temp. -150°C when it is other compound.
COPYRIGHT: (C)1979,JPO&Japio
JP4099578A 1978-04-07 1978-04-07 Maleimide-substituted carboxylic acid ester Pending JPS54132585A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4099578A JPS54132585A (en) 1978-04-07 1978-04-07 Maleimide-substituted carboxylic acid ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4099578A JPS54132585A (en) 1978-04-07 1978-04-07 Maleimide-substituted carboxylic acid ester

Publications (1)

Publication Number Publication Date
JPS54132585A true JPS54132585A (en) 1979-10-15

Family

ID=12595999

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4099578A Pending JPS54132585A (en) 1978-04-07 1978-04-07 Maleimide-substituted carboxylic acid ester

Country Status (1)

Country Link
JP (1) JPS54132585A (en)

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