JPS5392753A - Pro-drug compounds as antiinflammatory steroids and pharmaceutical composition containing the same - Google Patents

Pro-drug compounds as antiinflammatory steroids and pharmaceutical composition containing the same

Info

Publication number
JPS5392753A
JPS5392753A JP12291277A JP12291277A JPS5392753A JP S5392753 A JPS5392753 A JP S5392753A JP 12291277 A JP12291277 A JP 12291277A JP 12291277 A JP12291277 A JP 12291277A JP S5392753 A JPS5392753 A JP S5392753A
Authority
JP
Japan
Prior art keywords
pro
pharmaceutical composition
same
composition containing
drug compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12291277A
Other languages
English (en)
Japanese (ja)
Inventor
Esu Boodaa Nikorae
Bii Suroon Kenesu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanebo Ltd
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Publication of JPS5392753A publication Critical patent/JPS5392753A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP12291277A 1976-10-12 1977-10-12 Pro-drug compounds as antiinflammatory steroids and pharmaceutical composition containing the same Pending JPS5392753A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/731,373 US4069322A (en) 1976-10-12 1976-10-12 Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids

Publications (1)

Publication Number Publication Date
JPS5392753A true JPS5392753A (en) 1978-08-15

Family

ID=24939222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12291277A Pending JPS5392753A (en) 1976-10-12 1977-10-12 Pro-drug compounds as antiinflammatory steroids and pharmaceutical composition containing the same

Country Status (10)

Country Link
US (1) US4069322A (enExample)
JP (1) JPS5392753A (enExample)
AU (1) AU513155B2 (enExample)
BE (1) BE859613A (enExample)
CA (1) CA1100482A (enExample)
DE (1) DE2745948A1 (enExample)
FR (1) FR2367777A1 (enExample)
GB (1) GB1589787A (enExample)
SE (1) SE433220B (enExample)
ZA (1) ZA776014B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235887A (en) * 1977-04-13 1980-11-25 The Upjohn Company Process for therapeutic treatment
US4221787A (en) * 1978-03-28 1980-09-09 Interx Research Corporation Esteramide prodrugs of anti-inflammatory corticosteroids
US4279900A (en) * 1978-07-13 1981-07-21 Intrex Research Corporation Prodrugs for the improved delivery of halogen-containing glucocorticosteroids
US4213978A (en) * 1978-12-05 1980-07-22 Interx Research Corporation Anti-acne and anti-seborrhea prodrug derivatives of progesterone
US4268441A (en) * 1979-03-13 1981-05-19 Interx Research Corporation Prodrugs for improved bioavailability of certain Δ4 -3-ketosteroidal sex hormones
ATE126695T1 (de) * 1982-05-18 1995-09-15 Univ Florida Gehirnspezifische arzneimittelabgabe.
WO1984004041A1 (en) * 1983-04-14 1984-10-25 Univ California Colon-specific drug delivery system
US5886162A (en) * 1989-11-03 1999-03-23 Research Foundation Of State University Of New York Lipophilic diakylaminomethylene prodrug derivatives for the inhibition of replication of viruses
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
CN116023425B (zh) * 2023-03-28 2023-06-20 南京师范大学 曲安西龙衍生物及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB959377A (en) * 1959-10-12 1964-06-03 Scherico Ltd Dioxy steroids and processes for their preparation
CH432513A (de) * 1961-06-13 1967-03-31 Vismara Francesco Spa Verfahren zur Herstellung neuer, 1'-substituierter 17a,21-(1'-Alkoxy)-methylendioxysteroide
US3119816A (en) * 1961-12-19 1964-01-28 Shionogi & Co 2'-substituted thiazolo[5', 4'-16, 17] steroid of androstane series
GB1043347A (en) * 1963-05-10 1966-09-21 Glaxo Lab Ltd 17,21-orthoesters of steroids
IT1056712B (it) * 1967-04-01 1982-02-20 Vismara F Spa Derivati steroidali

Also Published As

Publication number Publication date
CA1100482A (en) 1981-05-05
AU513155B2 (en) 1980-11-20
AU2957277A (en) 1979-04-26
FR2367777B1 (enExample) 1980-10-17
US4069322A (en) 1978-01-17
ZA776014B (en) 1978-05-30
FR2367777A1 (fr) 1978-05-12
GB1589787A (en) 1981-05-20
DE2745948A1 (de) 1978-04-13
SE433220B (sv) 1984-05-14
SE7711385L (sv) 1978-04-13
BE859613A (fr) 1978-02-01

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