JPS5371077A - Polyoxidize labdane derivative and process for preparing same - Google Patents

Polyoxidize labdane derivative and process for preparing same

Info

Publication number
JPS5371077A
JPS5371077A JP1431877A JP1431877A JPS5371077A JP S5371077 A JPS5371077 A JP S5371077A JP 1431877 A JP1431877 A JP 1431877A JP 1431877 A JP1431877 A JP 1431877A JP S5371077 A JPS5371077 A JP S5371077A
Authority
JP
Japan
Prior art keywords
polyoxidize
preparing same
labdane
derivative
labdane derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1431877A
Other languages
English (en)
Inventor
Shingu Bajiyuwa Barubiru
Basudebu Buhatsuto Sujiyata
Donauaa Horusuto
Jiyon Do Suuza Noeru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS5371077A publication Critical patent/JPS5371077A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
JP1431877A 1976-12-03 1977-02-14 Polyoxidize labdane derivative and process for preparing same Pending JPS5371077A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762654796 DE2654796A1 (de) 1976-12-03 1976-12-03 Polyoxygenierte labdan-derivate

Publications (1)

Publication Number Publication Date
JPS5371077A true JPS5371077A (en) 1978-06-24

Family

ID=5994581

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1431877A Pending JPS5371077A (en) 1976-12-03 1977-02-14 Polyoxidize labdane derivative and process for preparing same

Country Status (13)

Country Link
US (1) US4134986A (ja)
JP (1) JPS5371077A (ja)
BE (1) BE852060A (ja)
DE (1) DE2654796A1 (ja)
DK (1) DK55377A (ja)
ES (1) ES456287A1 (ja)
FI (1) FI770401A (ja)
FR (1) FR2372822A1 (ja)
IT (1) IT1075566B (ja)
NL (1) NL7702129A (ja)
NO (1) NO770401L (ja)
SE (1) SE7701310L (ja)
ZA (1) ZA771052B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6479167A (en) * 1987-06-29 1989-03-24 Nippon Kayaku Kk Novel synthesis of 6-acyl-7-deacetylforskolin derivative

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782082A (en) * 1982-12-27 1988-11-01 Schering Corporation Method for treating allergic reactions with Forskolin
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
US4564626A (en) * 1983-04-01 1986-01-14 Schering Corporation Methods of inducing bronchodilation
DE3314999A1 (de) * 1983-04-26 1985-03-14 Behringwerke Ag, 3550 Marburg Verwendung des diterpen-derivates forskolin zur immunstimulation
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
US4751224A (en) * 1983-07-21 1988-06-14 Brown University Research Foundation Treatment of metastasis
WO1985003637A1 (en) * 1984-02-24 1985-08-29 Halprin Kenneth M Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
US4783457A (en) * 1984-05-01 1988-11-08 The General Hospital Corporation Pest controlling agents
US4678775A (en) * 1984-05-01 1987-07-07 Nathanson James A Method of controlling pests
SE454051B (sv) * 1984-10-09 1988-03-28 Marcus Lindblom Som bergdubb tjenande fasthallningsorgan
MC1710A1 (fr) * 1984-11-26 1986-09-22 Ciba Geigy Ag Composes azotes de derives oxo
DE3502686A1 (de) * 1985-01-26 1986-08-14 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel
US4639446A (en) * 1984-12-14 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes, pharmaceutical compositions and use
DE3502685A1 (de) * 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4672115A (en) * 1984-12-14 1987-06-09 Hoechst-Roussel Pharmaceuticals Inc. Process for preparing aminoacyllabdanes
US4673752A (en) * 1984-12-14 1987-06-16 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes
DE3581725D1 (de) * 1984-12-14 1991-03-14 Hoechst Roussel Pharma Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
IN163242B (ja) 1985-05-03 1988-08-27 Hoechst India
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
US4734513A (en) * 1986-03-31 1988-03-29 Hoechst-Roussel Pharmaceuticals Inc. Method of synthesizing forskolin from 9-deoxyforskolin
US5008407A (en) * 1986-03-31 1991-04-16 Hoechst-Roussel Pharmaceuticals Inc. Method of synthesizing forskolin from 9-deoxyforskolin
US5247097A (en) * 1986-08-28 1993-09-21 Hoechst-Roussel Pharmaceuticals Incorporated Oxolabdanes
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
US4871764A (en) * 1986-11-20 1989-10-03 Hoechst-Roussel Pharmaceuticals, Inc. 12-Halogenated forskolin derivatives
US4978678A (en) * 1986-11-20 1990-12-18 Hoechst-Roussel Pharmaceuticals Inc. 12-halogenated forskolin derivatives
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4770376A (en) * 1987-03-19 1988-09-13 Lindblom Erik M Fastener device which functions as a rock dowel
DE3730748A1 (de) * 1987-06-06 1988-12-22 Hoechst Ag Neue polyoxygenierte labdanderivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5302730A (en) * 1987-06-29 1994-04-12 Nippon Kayaku Kk Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
US4909799A (en) * 1987-09-18 1990-03-20 Olav Thulesius Methods for preventing thrombosis; and surgical implant having reduced platelet deposition characteristics
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
DE68902811D1 (de) * 1988-11-19 1992-10-15 Hoechst Ag Pharmazeutische zusammensetzungen mit einem gehalt an labdan-di-terpenoid-derivaten und pyrimido(6,1-a)isochinolin-4-on-derivaten und ihre anwendung.
US4999351A (en) * 1989-01-11 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5145855A (en) * 1989-07-06 1992-09-08 Hoechst Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
JP3557095B2 (ja) * 1998-04-20 2004-08-25 高砂香料工業株式会社 メラニン産生抑制剤
ES2291333T3 (es) 2000-06-27 2008-03-01 Qualilife Pharmaceuticals Inc. Composiciones y metodos para el tratamiento de la respuesta sexual de las mujeres.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3631039A (en) * 1969-04-21 1971-12-28 Hoffmann La Roche 2-amino ethyl-2-hydroxy - 6-vinyl tetrahydropyrans tautomers and optical enantiomers thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6479167A (en) * 1987-06-29 1989-03-24 Nippon Kayaku Kk Novel synthesis of 6-acyl-7-deacetylforskolin derivative

Also Published As

Publication number Publication date
SE7701310L (sv) 1978-06-04
DK55377A (da) 1978-06-04
ZA771052B (en) 1978-02-22
US4134986A (en) 1979-01-16
FI770401A (fi) 1978-06-04
NO770401L (no) 1978-06-06
ES456287A1 (es) 1978-06-01
DE2654796A1 (de) 1978-06-08
IT1075566B (it) 1985-04-22
FR2372822B1 (ja) 1980-02-01
FR2372822A1 (fr) 1978-06-30
BE852060A (fr) 1977-09-05
NL7702129A (nl) 1978-06-06

Similar Documents

Publication Publication Date Title
JPS5371077A (en) Polyoxidize labdane derivative and process for preparing same
BG37375A3 (en) Method for preparing prolinic derivatives
JPS5387399A (en) Benzocycloheptapyrazolopyridine derivative and process for preparing same
HU172711B (hu) Sposob poluchenija proizvodnykh piperidil-indola
JPS5321134A (en) 44hydroxyphenylalkanolamine derivatives and process for preparation therefor
JPS5371070A (en) Isooxazole derivative and process for preparing same
HU178040B (en) Process for preparing 8-aza-prostaglandin derivatives
JPS52118493A (en) Cephalospoline derivatives and process for preparing same
JPS5368761A (en) Substituted acetonaphtone process for preparing same ferfume using same and intermediate for preparing same
JPS52139085A (en) 22allylpiperazine derivative and method for its preparation
JPS52111593A (en) 99substitutedd88azapurine and process for preparing same
HU173606B (hu) Sposob poluchenija proizvodnykh benzo-sul'fo-karbamida
JPS52125198A (en) Naphtilysine derivatives and process for preparing same
HU178806B (en) Process for preparing benzyl-cyano-acetal derivatives
IL52488A (en) 9-desacetyl daunoruiin derivatives and process for their preparation
HU174982B (hu) Sposob poluchenija proizvodnykh 17al'fa-gidroksi-pregnan-20-ona
JPS5365880A (en) Cydononeimineeacyl derivative and process for preparing same
JPS5371069A (en) Isooxazole derivative and process for preparing same
JPS52144659A (en) 22chloroo66methyll44benzylphenol and process for preparing same
JPS537649A (en) Process for preparing prostaglandineea and certain derivatives
BG34760A3 (en) Method for preparing nitroalkanolic derivatives
JPS52108995A (en) Cyanoalklyureido cephalospolines and process for preparing same
HU177936B (en) Process for preparing 1-dialkylamino-2-alkin-4-ol derivatives
HU176954B (hu) Sposob poluchenija proizvodnykh cis-geksagidro-dibenzopiranona
JPS5382799A (en) Substituted pyroloquinolinecarboxylate and process for preparing same