JPS5341415A - Preparation of novel antitumor agent - Google Patents

Preparation of novel antitumor agent

Info

Publication number
JPS5341415A
JPS5341415A JP7642577A JP7642577A JPS5341415A JP S5341415 A JPS5341415 A JP S5341415A JP 7642577 A JP7642577 A JP 7642577A JP 7642577 A JP7642577 A JP 7642577A JP S5341415 A JPS5341415 A JP S5341415A
Authority
JP
Japan
Prior art keywords
preparation
antitumor agent
novel antitumor
novel
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7642577A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6222995B2 (de
Inventor
Nobishikii Bashirii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPS5341415A publication Critical patent/JPS5341415A/ja
Publication of JPS6222995B2 publication Critical patent/JPS6222995B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36—Amides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP7642577A 1976-06-28 1977-06-27 Preparation of novel antitumor agent Granted JPS5341415A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT472876A AT377988B (de) 1976-06-28 1976-06-28 Verfahren zur herstellung von neuen phosphorderivaten von alkaloiden

Publications (2)

Publication Number Publication Date
JPS5341415A true JPS5341415A (en) 1978-04-14
JPS6222995B2 JPS6222995B2 (de) 1987-05-20

Family

ID=3567633

Family Applications (2)

Application Number Title Priority Date Filing Date
JP7642577A Granted JPS5341415A (en) 1976-06-28 1977-06-27 Preparation of novel antitumor agent
JP61252786A Granted JPS63183540A (ja) 1976-06-28 1986-10-23 アルカロイドのトリエチレンチオ燐酸アミドの製法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP61252786A Granted JPS63183540A (ja) 1976-06-28 1986-10-23 アルカロイドのトリエチレンチオ燐酸アミドの製法

Country Status (4)

Country Link
JP (2) JPS5341415A (de)
AT (1) AT377988B (de)
DK (1) DK283377A (de)
FR (1) FR2366020A1 (de)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58501074A (ja) * 1981-07-13 1983-07-07 ノビツキ−，バツシル アルカロイド化合物
JPH09510459A (ja) * 1994-03-18 1997-10-21 ヴァジル ノヴィッキイ， 内分泌障害治療のためのアルカロイド燐誘導体の使用
JPH11505851A (ja) * 1995-06-01 1999-05-25 ノーヴッキー、ヴァーシル 放射線障害の処置のための薬剤
US6376516B1 (en) 1997-08-19 2002-04-23 Emory University Noscapine and noscapine derivatives, useful as anticancer agents
JP2005509006A (ja) * 2001-11-15 2005-04-07 ノヴィッキイ、 ヴァジル アルカロイドを反応させる製造方法および反応生成物の薬剤調製の使用
JP2006520763A (ja) * 2003-03-18 2006-09-14 ノヴィッキイ、 ヴァジル ４級ケリドニン及びアルカロイド誘導体類、それらの製造法、及び医薬の製造でのそれらの使用
JP2018527301A (ja) * 2015-06-24 2018-09-20 スレッシュホールド ファーマシューティカルズ， インコーポレイテッド Ｄｎａアルキル化剤を含有するアジリジン

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US7823627B2 (en) * 2006-05-19 2010-11-02 Exxonmobil Research & Engineering Company Device for generating acoustic and/or vibration energy for heat exchanger tubes

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58501074A (ja) * 1981-07-13 1983-07-07 ノビツキ−，バツシル アルカロイド化合物
JPH09510459A (ja) * 1994-03-18 1997-10-21 ヴァジル ノヴィッキイ， 内分泌障害治療のためのアルカロイド燐誘導体の使用
JPH11505851A (ja) * 1995-06-01 1999-05-25 ノーヴッキー、ヴァーシル 放射線障害の処置のための薬剤
US6376516B1 (en) 1997-08-19 2002-04-23 Emory University Noscapine and noscapine derivatives, useful as anticancer agents
JP2005509006A (ja) * 2001-11-15 2005-04-07 ノヴィッキイ、 ヴァジル アルカロイドを反応させる製造方法および反応生成物の薬剤調製の使用
JP2006520763A (ja) * 2003-03-18 2006-09-14 ノヴィッキイ、 ヴァジル ４級ケリドニン及びアルカロイド誘導体類、それらの製造法、及び医薬の製造でのそれらの使用
JP2018527301A (ja) * 2015-06-24 2018-09-20 スレッシュホールド ファーマシューティカルズ， インコーポレイテッド Ｄｎａアルキル化剤を含有するアジリジン

Also Published As

Publication number Publication date
JPH0342279B2 (de) 1991-06-26
JPS6222995B2 (de) 1987-05-20
DK283377A (da) 1977-12-29
AT377988B (de) 1985-05-28
JPS63183540A (ja) 1988-07-28
ATA472876A (de) 1984-10-15
FR2366020A1 (fr) 1978-04-28

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