JPS5315361A - Production of novel corticoide and pharmaceutical agent containing same with excellent antiiinflamatory action* - Google Patents

Production of novel corticoide and pharmaceutical agent containing same with excellent antiiinflamatory action*

Info

Publication number
JPS5315361A
JPS5315361A JP8493377A JP8493377A JPS5315361A JP S5315361 A JPS5315361 A JP S5315361A JP 8493377 A JP8493377 A JP 8493377A JP 8493377 A JP8493377 A JP 8493377A JP S5315361 A JPS5315361 A JP S5315361A
Authority
JP
Japan
Prior art keywords
antiiinflamatory
corticoide
novel
action
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8493377A
Other languages
English (en)
Japanese (ja)
Inventor
Kerupu Ururitsuhi
Buiihieruto Ruudorufu
Buento Hansu
Furiitoritsuhi Katsupu Yoahimu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS5315361A publication Critical patent/JPS5315361A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP8493377A 1976-07-16 1977-07-15 Production of novel corticoide and pharmaceutical agent containing same with excellent antiiinflamatory action* Pending JPS5315361A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2632678A DE2632678C2 (de) 1976-07-16 1976-07-16 6α-Fluor-12α-Halogen-Kortikoide und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
JPS5315361A true JPS5315361A (en) 1978-02-13

Family

ID=5983515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8493377A Pending JPS5315361A (en) 1976-07-16 1977-07-15 Production of novel corticoide and pharmaceutical agent containing same with excellent antiiinflamatory action*

Country Status (11)

Country Link
JP (1) JPS5315361A (enExample)
AT (1) AT355743B (enExample)
BE (1) BE856862A (enExample)
CH (1) CH627191A5 (enExample)
DE (1) DE2632678C2 (enExample)
DK (1) DK323877A (enExample)
FR (1) FR2358421A1 (enExample)
GB (1) GB1589585A (enExample)
IT (1) IT1125789B (enExample)
LU (1) LU77768A1 (enExample)
NL (1) NL7707920A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2244000B (en) * 1990-05-18 1993-09-22 Teasdale S Mattress
MX2012010824A (es) 2010-03-26 2012-10-10 Galderma Res & Dev Metodos y composiciones mejoradas para tratamiento seguro y efectivo del eritema.
EP2768502A2 (en) 2011-10-19 2014-08-27 Galderma S.A. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053837A (en) * 1958-10-01 1962-09-11 Olin Mathieson 16, 17-acetal and ketal derivatives of 6alpha, 12alpha-dihalo-16alpha, 17alpha-dihydroxy steroids of the pregnane series; and intermediates therefor
GB1179547A (en) * 1965-12-22 1970-01-28 Squibb & Sons Inc 01beta,12beta-Oxido-16alpha-Methyl-Pregnenes

Also Published As

Publication number Publication date
ATA504777A (de) 1979-08-15
DE2632678A1 (de) 1978-01-26
GB1589585A (en) 1981-05-13
LU77768A1 (enExample) 1977-10-17
NL7707920A (nl) 1978-01-18
FR2358421A1 (fr) 1978-02-10
BE856862A (fr) 1978-01-16
DK323877A (da) 1978-01-17
AT355743B (de) 1980-03-25
CH627191A5 (en) 1981-12-31
IT1125789B (it) 1986-05-14
FR2358421B1 (enExample) 1979-05-11
DE2632678C2 (de) 1986-02-27

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