JPS5283399A - Process for preparing vincamine and epivincamine from ***tabelsonine - Google Patents
Process for preparing vincamine and epivincamine from ***tabelsonineInfo
- Publication number
- JPS5283399A JPS5283399A JP13854276A JP13854276A JPS5283399A JP S5283399 A JPS5283399 A JP S5283399A JP 13854276 A JP13854276 A JP 13854276A JP 13854276 A JP13854276 A JP 13854276A JP S5283399 A JPS5283399 A JP S5283399A
- Authority
- JP
- Japan
- Prior art keywords
- tabelsonine
- epivincamine
- vincamine
- preparing
- preparing vincamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title 2
- RXPRRQLKFXBCSJ-HLAWJBBLSA-N 16-epivincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-HLAWJBBLSA-N 0.000 title 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960002726 vincamine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7535529A FR2332280A1 (fr) | 1975-11-20 | 1975-11-20 | Procede de preparation de vincamine et d'epivincamine a partir de la (-) tabersonine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5283399A true JPS5283399A (en) | 1977-07-12 |
Family
ID=9162680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13854276A Pending JPS5283399A (en) | 1975-11-20 | 1976-11-19 | Process for preparing vincamine and epivincamine from ***tabelsonine |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5283399A (OSRAM) |
| BE (1) | BE848475A (OSRAM) |
| DE (1) | DE2652165C2 (OSRAM) |
| FR (1) | FR2332280A1 (OSRAM) |
| HU (1) | HU177706B (OSRAM) |
| SU (1) | SU657751A3 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2396759A1 (fr) * | 1977-07-06 | 1979-02-02 | Omnium Chimique Sa | Nouveaux composes heterocycliques, derives de la vincamine, leur preparation et leur application comme medicaments, notamment dans le domaine des insuffisances cardio-circulatoires, cerebro-vasculaires ou respiratoires |
| DE2745415C2 (de) * | 1977-10-08 | 1983-06-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von (-)-Vincamin |
| CH646166A5 (it) * | 1980-09-30 | 1984-11-15 | Linnea Sa | Procedimento di sintesi parziale della vincamina e di alcaloidi indolici correlati. |
| HU185255B (en) * | 1981-04-23 | 1984-12-28 | Richter Gedeon Vegyeszet | New process preparing compounds with eburnane skeleton by means of the oxidative transformation of tabersonine or dihydrotabersonine |
| CH657617A5 (it) * | 1982-10-25 | 1986-09-15 | Istituto Chemioterapico Di Lod | Procedimento per la preparazione di vincamina. |
| LU84664A1 (fr) * | 1983-02-25 | 1984-11-08 | Onmichem S A | Alkyl-4-indolonaphtyridines et leur application therapeutique |
-
1975
- 1975-11-20 FR FR7535529A patent/FR2332280A1/fr active Granted
-
1976
- 1976-11-16 DE DE19762652165 patent/DE2652165C2/de not_active Expired
- 1976-11-18 BE BE172465A patent/BE848475A/xx not_active IP Right Cessation
- 1976-11-19 JP JP13854276A patent/JPS5283399A/ja active Pending
- 1976-11-19 SU SU762421703A patent/SU657751A3/ru active
- 1976-11-19 HU HUOI000208 patent/HU177706B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2652165A1 (de) | 1977-06-02 |
| FR2332280B1 (OSRAM) | 1979-05-11 |
| SU657751A3 (ru) | 1979-04-15 |
| BE848475A (fr) | 1977-03-16 |
| HU177706B (en) | 1981-12-28 |
| FR2332280A1 (fr) | 1977-06-17 |
| DE2652165C2 (de) | 1982-11-25 |
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