JPS5234982A - Preparation of protease antagonist - Google Patents

Preparation of protease antagonist

Info

Publication number
JPS5234982A
JPS5234982A JP50111337A JP11133775A JPS5234982A JP S5234982 A JPS5234982 A JP S5234982A JP 50111337 A JP50111337 A JP 50111337A JP 11133775 A JP11133775 A JP 11133775A JP S5234982 A JPS5234982 A JP S5234982A
Authority
JP
Japan
Prior art keywords
preparation
antagonist
protease
protease antagonist
cuiture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50111337A
Other languages
Japanese (ja)
Other versions
JPS5434834B2 (en
Inventor
Shinichi Kojima
Kazuro Nakamura
Shizuka Koide
Shigeo Ogino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP50111337A priority Critical patent/JPS5234982A/en
Priority to DE2640420A priority patent/DE2640420C2/en
Priority to AU17548/76A priority patent/AU490062B2/en
Priority to DE2660964A priority patent/DE2660964C2/de
Priority to US05/721,503 priority patent/US4091093A/en
Priority to SE7609960A priority patent/SE436137B/en
Priority to NL7610032A priority patent/NL7610032A/en
Priority to GB37487/76A priority patent/GB1519101A/en
Priority to FR7627301A priority patent/FR2323394A1/en
Priority to CA260,917A priority patent/CA1066212A/en
Priority to BE1007615A priority patent/BE846035A/en
Priority to CH1161976A priority patent/CH633964A5/en
Publication of JPS5234982A publication Critical patent/JPS5234982A/en
Priority to US05/884,623 priority patent/US4206283A/en
Publication of JPS5434834B2 publication Critical patent/JPS5434834B2/ja
Priority to CA000416199A priority patent/CA1159000B/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: Novel protease antagonist, S-735, is prepared the cuiture of a microorganism belonging to Streptomyces genus.
COPYRIGHT: (C)1977,JPO&Japio
JP50111337A 1975-09-12 1975-09-12 Preparation of protease antagonist Granted JPS5234982A (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
JP50111337A JPS5234982A (en) 1975-09-12 1975-09-12 Preparation of protease antagonist
DE2640420A DE2640420C2 (en) 1975-09-12 1976-09-08 Peptides designated as procidins, processes for their production and agents containing these compounds
AU17548/76A AU490062B2 (en) 1976-09-08 PROTEASE inhibitors
DE2660964A DE2660964C2 (en) 1975-09-12 1976-09-08
US05/721,503 US4091093A (en) 1975-09-12 1976-09-08 Protease inhibitors
GB37487/76A GB1519101A (en) 1975-09-12 1976-09-09 Protease inhibitors
NL7610032A NL7610032A (en) 1975-09-12 1976-09-09 MEANS FOR INHIBITING PROTEASE.
SE7609960A SE436137B (en) 1975-09-12 1976-09-09 PROCEDURE FOR THE PREPARATION OF PROTEAS INHIBITORS, CALLED PROCIDINES, BY CULTIVATION OF THE NEW STOCK ATCC 31233, RELATED TO ACTINOMADURA
FR7627301A FR2323394A1 (en) 1975-09-12 1976-09-10 NEW PROCIDINS USEFUL AS PROTEASE INHIBITORS
CA260,917A CA1066212A (en) 1975-09-12 1976-09-10 Protease inhibitors
BE1007615A BE846035A (en) 1975-09-12 1976-09-10 NEW PROCIDINS USEFUL AS PROTEASS INHIBITORS
CH1161976A CH633964A5 (en) 1975-09-12 1976-09-13 METHOD FOR PRODUCING PEPSIN INHIBITORS.
US05/884,623 US4206283A (en) 1975-09-12 1978-03-06 Protease inhibitors
CA000416199A CA1159000B (en) 1975-09-12 1982-11-23 Protease inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50111337A JPS5234982A (en) 1975-09-12 1975-09-12 Preparation of protease antagonist

Publications (2)

Publication Number Publication Date
JPS5234982A true JPS5234982A (en) 1977-03-17
JPS5434834B2 JPS5434834B2 (en) 1979-10-29

Family

ID=14558630

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50111337A Granted JPS5234982A (en) 1975-09-12 1975-09-12 Preparation of protease antagonist

Country Status (2)

Country Link
JP (1) JPS5234982A (en)
BE (1) BE846035A (en)

Also Published As

Publication number Publication date
BE846035A (en) 1976-12-31
JPS5434834B2 (en) 1979-10-29

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