JPS5231821A - Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use - Google Patents

Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use

Info

Publication number
JPS5231821A
JPS5231821A JP50108197A JP10819775A JPS5231821A JP S5231821 A JPS5231821 A JP S5231821A JP 50108197 A JP50108197 A JP 50108197A JP 10819775 A JP10819775 A JP 10819775A JP S5231821 A JPS5231821 A JP S5231821A
Authority
JP
Japan
Prior art keywords
dried
lts
dehydroepiandrosterone sulfate
injection use
freeze
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50108197A
Other languages
English (en)
Japanese (ja)
Other versions
JPS578086B2 (enExample
Inventor
Isao Sugimoto
Yoko Sawase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanebo Ltd
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Priority to JP50108197A priority Critical patent/JPS5231821A/ja
Priority to SE7609443A priority patent/SE439586B/xx
Priority to GB35659/76A priority patent/GB1561360A/en
Priority to IL50376A priority patent/IL50376A/xx
Priority to US05/719,278 priority patent/US4061744A/en
Priority to DK396576A priority patent/DK153124C/da
Priority to BE7000878A priority patent/BE845795A/nl
Priority to HU76KA1471A priority patent/HU173475B/hu
Priority to SU762395947A priority patent/SU1072789A3/ru
Priority to DE2639849A priority patent/DE2639849C2/de
Priority to CA260,475A priority patent/CA1047404A/en
Priority to ZA765289A priority patent/ZA765289B/xx
Priority to NLAANVRAGE7609833,A priority patent/NL183385C/xx
Priority to CS765741A priority patent/CS216160B2/cs
Priority to ES451256A priority patent/ES451256A1/es
Priority to DD194650A priority patent/DD127381A5/xx
Priority to AU17486/76A priority patent/AU498543B2/en
Priority to FR7626734A priority patent/FR2322605A1/fr
Publication of JPS5231821A publication Critical patent/JPS5231821A/ja
Publication of JPS578086B2 publication Critical patent/JPS578086B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP50108197A 1975-09-05 1975-09-05 Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use Granted JPS5231821A (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
JP50108197A JPS5231821A (en) 1975-09-05 1975-09-05 Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use
SE7609443A SE439586B (sv) 1975-09-05 1976-08-26 Sett att framstella ett stabilt farmaceutiskt torrpreparat av ett alkalimetallsalt av dehydroepiandrosteronsulfat
GB35659/76A GB1561360A (en) 1975-09-05 1976-08-27 Pharmaceutical preparations
IL50376A IL50376A (en) 1975-09-05 1976-08-30 Method for preparation a stable preparation of water soluble salts or dehydro-epiandrosterone sulfate for parenteral administration
US05/719,278 US4061744A (en) 1975-09-05 1976-08-31 Stable preparation of water-soluble salts of dehydroepiandrosterone sulfate for parenteral administration
DK396576A DK153124C (da) 1975-09-05 1976-09-02 Fremgangsmaade til fremstilling af et stabilt toerpraeparat af et alkalimetalsalt af dehydroepiandrosteronsulfat, som er beregnet til parenteral administration
BE7000878A BE845795A (nl) 1975-09-05 1976-09-02 Werkwijze ter bereiding van stabiele preparaten van wateroplosbare zouten van dehydro-epiandrosteronsulfaat voor parenterale toediening
HU76KA1471A HU173475B (hu) 1975-09-05 1976-09-03 Sposob poluchenija stabil'nogo farmacevticheskogo preparata soderzhahhego vodorastvorimye soli degidro-epi-androsteron-sul'fata dlja parenteral'nojj dozirovki
SU762395947A SU1072789A3 (ru) 1975-09-05 1976-09-03 Способ получени соли стероида дл парентерального введени
DE2639849A DE2639849C2 (de) 1975-09-05 1976-09-03 Stabile Präparate wasserlöslicher Salze von Dehydroepiandrosteronsulfat zur parenteralen Verabreichung
CA260,475A CA1047404A (en) 1975-09-05 1976-09-03 Stable preparation of water-soluble salts of dehydroeplandrosterone sulfate for parenteral administration
ZA765289A ZA765289B (en) 1975-09-05 1976-09-03 Stable preparation of water-soluble salts of dehydroepiandrosterone sulfate for parenteral administration
NLAANVRAGE7609833,A NL183385C (nl) 1975-09-05 1976-09-03 Werkwijze voor het bereiden van een farmaceutisch preparaat voor parenterale toediening van een zout van dehydro-epiandrosteronsulfaat.
CS765741A CS216160B2 (en) 1975-09-05 1976-09-03 Method of stabilization of the pharmaceutical preparation with contents of salt of alcalic metal with dehydroepiandrosteronsulphate
ES451256A ES451256A1 (es) 1975-09-05 1976-09-04 Un metodo para producir una preparacion farmaceutica establepara administracion parenteral.
DD194650A DD127381A5 (enExample) 1975-09-05 1976-09-06
AU17486/76A AU498543B2 (en) 1975-09-05 1976-09-06 Water soluble salts of dehydroepiandrosterone sulfate
FR7626734A FR2322605A1 (fr) 1975-09-05 1976-09-06 Procede pour l'obtention d'une preparation stable du sulfate de dehydroepiandrosterone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50108197A JPS5231821A (en) 1975-09-05 1975-09-05 Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use

Publications (2)

Publication Number Publication Date
JPS5231821A true JPS5231821A (en) 1977-03-10
JPS578086B2 JPS578086B2 (enExample) 1982-02-15

Family

ID=14478465

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50108197A Granted JPS5231821A (en) 1975-09-05 1975-09-05 Method of manufacturing freeze-dried dehydroepiandrosterone sulfate sa lts for injection use

Country Status (3)

Country Link
JP (1) JPS5231821A (enExample)
BE (1) BE845795A (enExample)
ZA (1) ZA765289B (enExample)

Also Published As

Publication number Publication date
BE845795A (nl) 1977-03-02
JPS578086B2 (enExample) 1982-02-15
ZA765289B (en) 1977-08-31

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