JPS5218702B1 - - Google Patents

Info

Publication number
JPS5218702B1
JPS5218702B1 JP48133105A JP13310573A JPS5218702B1 JP S5218702 B1 JPS5218702 B1 JP S5218702B1 JP 48133105 A JP48133105 A JP 48133105A JP 13310573 A JP13310573 A JP 13310573A JP S5218702 B1 JPS5218702 B1 JP S5218702B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP48133105A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5218702B1 publication Critical patent/JPS5218702B1/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP48133105A 1968-12-18 1973-11-29 Pending JPS5218702B1 (US20070244113A1-20071018-C00087.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB60083/68A GB1237008A (en) 1968-12-18 1968-12-18 Novel indoline derivatives

Publications (1)

Publication Number Publication Date
JPS5218702B1 true JPS5218702B1 (US20070244113A1-20071018-C00087.png) 1977-05-24

Family

ID=10484978

Family Applications (2)

Application Number Title Priority Date Filing Date
JP44101382A Pending JPS5011915B1 (US20070244113A1-20071018-C00087.png) 1968-12-18 1969-12-18
JP48133105A Pending JPS5218702B1 (US20070244113A1-20071018-C00087.png) 1968-12-18 1973-11-29

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP44101382A Pending JPS5011915B1 (US20070244113A1-20071018-C00087.png) 1968-12-18 1969-12-18

Country Status (10)

Country Link
US (2) US3644403A (US20070244113A1-20071018-C00087.png)
JP (2) JPS5011915B1 (US20070244113A1-20071018-C00087.png)
BE (1) BE743250A (US20070244113A1-20071018-C00087.png)
BR (1) BR6915242D0 (US20070244113A1-20071018-C00087.png)
CH (2) CH551411A (US20070244113A1-20071018-C00087.png)
DE (1) DE1963182C2 (US20070244113A1-20071018-C00087.png)
ES (1) ES374644A2 (US20070244113A1-20071018-C00087.png)
FR (1) FR2026492B2 (US20070244113A1-20071018-C00087.png)
GB (1) GB1237008A (US20070244113A1-20071018-C00087.png)
SE (1) SE360862B (US20070244113A1-20071018-C00087.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS556986U (US20070244113A1-20071018-C00087.png) * 1978-06-30 1980-01-17

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882236A (en) * 1973-12-26 1975-05-06 Lilly Co Eli Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension
US4080330A (en) * 1975-06-23 1978-03-21 Delmar Chemicals Limited Phenylindolines and process for their production
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
FR2420536A1 (fr) * 1978-03-22 1979-10-19 Roussel Uclaf Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments
DE2933636A1 (de) * 1978-08-30 1980-03-20 Sandoz Ag Neue n-phenylindolinderivate, ihre herstellung und pharmazeutische praeparate, welche diese verbindungen enthalten
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
US4476307A (en) * 1982-09-20 1984-10-09 Pfizer Inc. Heteroylidene indolone compounds
US4977178A (en) * 1982-09-20 1990-12-11 Pfizer Inc. Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents
US4879391A (en) * 1982-09-20 1989-11-07 Pfizer Inc. 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents
US4694017A (en) * 1983-05-19 1987-09-15 Otsuka Pharmaceutical Co., Ltd. 2-amido 3(oxindol-3-yl)propionic acids having antiulcer activity
US5229413A (en) * 1989-05-05 1993-07-20 G. D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
WO1996004274A1 (en) * 1994-08-02 1996-02-15 Merck Sharp & Dohme Limited Azetidine, pyrrolidine and piperidine derivatives
AU5877500A (en) * 1999-06-15 2001-01-02 Neurogen Corporation Piperidinyl and piperazinyl substituted benzofused lactams

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3184466A (en) * 1965-05-18 Beta amino butyrylxnbqlines
US2759935A (en) * 1953-02-18 1956-08-21 Bristol Lab Inc Substituted 3-phenyloxindoles
GB1154976A (en) * 1967-02-21 1969-06-11 Pfizer Ltd N-Phenyl Indoline Derivatives
US3468907A (en) * 1967-04-10 1969-09-23 Schering Corp Glyceryl esters of alpha-(1-aroyl-3-indolyl)alkanoic acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS556986U (US20070244113A1-20071018-C00087.png) * 1978-06-30 1980-01-17

Also Published As

Publication number Publication date
CH551412A (de) 1974-07-15
BE743250A (US20070244113A1-20071018-C00087.png) 1970-06-17
DE1963182C2 (de) 1983-05-19
JPS5011915B1 (US20070244113A1-20071018-C00087.png) 1975-05-07
DE1963182A1 (de) 1970-10-15
ES374644A2 (es) 1972-02-16
SE360862B (US20070244113A1-20071018-C00087.png) 1973-10-08
GB1237008A (en) 1971-06-30
US3720771A (en) 1973-03-13
FR2026492B2 (US20070244113A1-20071018-C00087.png) 1974-02-01
CH551411A (de) 1974-07-15
BR6915242D0 (pt) 1973-02-13
US3644403A (en) 1972-02-22
FR2026492A2 (US20070244113A1-20071018-C00087.png) 1970-09-18

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