AU5877500A - Piperidinyl and piperazinyl substituted benzofused lactams - Google Patents

Piperidinyl and piperazinyl substituted benzofused lactams

Info

Publication number
AU5877500A
AU5877500A AU58775/00A AU5877500A AU5877500A AU 5877500 A AU5877500 A AU 5877500A AU 58775/00 A AU58775/00 A AU 58775/00A AU 5877500 A AU5877500 A AU 5877500A AU 5877500 A AU5877500 A AU 5877500A
Authority
AU
Australia
Prior art keywords
piperidinyl
piperazinyl substituted
substituted benzofused
lactams
benzofused lactams
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58775/00A
Inventor
Andrew Thurkauf
He Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurogen Corp
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of AU5877500A publication Critical patent/AU5877500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
AU58775/00A 1999-06-15 2000-06-15 Piperidinyl and piperazinyl substituted benzofused lactams Abandoned AU5877500A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13918799P 1999-06-15 1999-06-15
US33336899A 1999-06-15 1999-06-15
US60139187 1999-06-15
US09333368 1999-06-15
PCT/US2000/016784 WO2000076981A1 (en) 1999-06-15 2000-06-15 Piperidinyl and piperazinyl substituted benzofused lactams

Publications (1)

Publication Number Publication Date
AU5877500A true AU5877500A (en) 2001-01-02

Family

ID=26836957

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58775/00A Abandoned AU5877500A (en) 1999-06-15 2000-06-15 Piperidinyl and piperazinyl substituted benzofused lactams

Country Status (2)

Country Link
AU (1) AU5877500A (en)
WO (1) WO2000076981A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514965B1 (en) * 1999-11-18 2003-02-04 Antex Pharma Inc. Substituted 1-benzazepines and derivatives thereof
EP1177792A3 (en) * 2000-07-27 2002-10-23 Pfizer Products Inc. Dopamine D4 Ligands for the treatment of novelty-seeking disorders
US7067550B2 (en) * 2000-11-03 2006-06-27 Massachusetts Institute Of Technology Treatments for neurotoxicity in Alzheimer's Disease
JP2004536079A (en) * 2001-05-16 2004-12-02 アンテックスファーマ・インコーポレーテッド Substituted 1-benzazepine and derivatives thereof
DE10358004A1 (en) 2003-12-11 2005-07-14 Abbott Gmbh & Co. Kg Ketolactam compounds and their use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1237008A (en) * 1968-12-18 1971-06-30 Pfizer Ltd Novel indoline derivatives
JPS5940149B2 (en) * 1977-11-09 1984-09-28 大塚製薬株式会社 Oxindole derivative
FR2420536A1 (en) * 1978-03-22 1979-10-19 Roussel Uclaf NEW DERIVATIVES OF 1,3-DIHYDRO 3- / 1- / 2- (2,3-DIHYDRO 1,4-BENZODIOXIN-2-YL) 2-HYDROXYETHYL / PIPERIDIN-4-YL / 2H-INDOL-2-ONE, PROCESS FOR THEIR PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS
FR2608157B1 (en) * 1986-12-11 1989-09-08 Roussel Uclaf NOVEL AZASPIRODECANE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING AND INTERMEDIATES THEREOF
CA2121148A1 (en) * 1992-08-19 1994-03-03 Satoru Nakai Apoptosis regulator
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
JP3748935B2 (en) * 1996-03-18 2006-02-22 大鵬薬品工業株式会社 Oxindole derivatives
WO1998054167A1 (en) * 1997-05-28 1998-12-03 Mitsubishi-Tokyo Pharmaceuticals, Inc. Indole compounds

Also Published As

Publication number Publication date
WO2000076981A1 (en) 2000-12-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase