JPS5214761A - Production of 9 alphaa fluorrsteroid and pharmaceutical composition containing the same - Google Patents

Production of 9 alphaa fluorrsteroid and pharmaceutical composition containing the same

Info

Publication number
JPS5214761A
JPS5214761A JP51087371A JP8737176A JPS5214761A JP S5214761 A JPS5214761 A JP S5214761A JP 51087371 A JP51087371 A JP 51087371A JP 8737176 A JP8737176 A JP 8737176A JP S5214761 A JPS5214761 A JP S5214761A
Authority
JP
Japan
Prior art keywords
fluorrsteroid
alphaa
production
same
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51087371A
Other languages
English (en)
Japanese (ja)
Inventor
Biora Mishieru
Karufuoda Yarosurafu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5214761A publication Critical patent/JPS5214761A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/009—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by only one oxygen atom doubly bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP51087371A 1975-07-23 1976-07-23 Production of 9 alphaa fluorrsteroid and pharmaceutical composition containing the same Pending JPS5214761A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH962075A CH611631A5 (en) 1975-07-23 1975-07-23 Process for the preparation of 11,12-unsaturated 9alpha-fluorosteroids

Publications (1)

Publication Number Publication Date
JPS5214761A true JPS5214761A (en) 1977-02-03

Family

ID=4353884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51087371A Pending JPS5214761A (en) 1975-07-23 1976-07-23 Production of 9 alphaa fluorrsteroid and pharmaceutical composition containing the same

Country Status (15)

Country Link
JP (1) JPS5214761A (de)
AT (1) AT353989B (de)
AU (1) AU505846B2 (de)
BE (1) BE844378A (de)
CH (1) CH611631A5 (de)
DE (1) DE2632550A1 (de)
DK (1) DK329976A (de)
ES (1) ES449989A1 (de)
FR (1) FR2318644A1 (de)
GB (1) GB1520356A (de)
IE (1) IE43926B1 (de)
NL (1) NL7608141A (de)
NZ (1) NZ181538A (de)
SE (1) SE7608369L (de)
ZA (1) ZA764405B (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5423643A (en) * 1977-07-22 1979-02-22 Aikawa Tekko Doctor blade stablizing apparatus
JPH04240294A (ja) * 1990-12-28 1992-08-27 Albany Internatl Corp 一体的装着手段付きドクターブレード及びその製造方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069074D1 (en) * 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5423643A (en) * 1977-07-22 1979-02-22 Aikawa Tekko Doctor blade stablizing apparatus
JPH04240294A (ja) * 1990-12-28 1992-08-27 Albany Internatl Corp 一体的装着手段付きドクターブレード及びその製造方法

Also Published As

Publication number Publication date
FR2318644A1 (fr) 1977-02-18
IE43926L (en) 1977-01-23
AU505846B2 (en) 1979-12-06
NL7608141A (nl) 1977-01-25
ATA539376A (de) 1979-05-15
BE844378A (fr) 1977-01-24
DE2632550A1 (de) 1977-02-10
DK329976A (da) 1977-01-24
FR2318644B1 (de) 1978-12-15
SE7608369L (sv) 1977-01-24
ZA764405B (en) 1977-08-31
AU1612176A (en) 1978-01-26
AT353989B (de) 1979-12-10
NZ181538A (en) 1978-09-20
ES449989A1 (es) 1977-12-01
IE43926B1 (en) 1981-07-01
CH611631A5 (en) 1979-06-15
GB1520356A (en) 1978-08-09

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