JPS52131526A - New compound of immunological adjuvant and method of preparation - Google Patents

New compound of immunological adjuvant and method of preparation

Info

Publication number
JPS52131526A
JPS52131526A JP4777777A JP4777777A JPS52131526A JP S52131526 A JPS52131526 A JP S52131526A JP 4777777 A JP4777777 A JP 4777777A JP 4777777 A JP4777777 A JP 4777777A JP S52131526 A JPS52131526 A JP S52131526A
Authority
JP
Japan
Prior art keywords
preparation
new compound
immunological adjuvant
immunological
adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4777777A
Other languages
English (en)
Japanese (ja)
Other versions
JPS638119B2 (xx
Inventor
Eichi Jiyoonzu Goodon
Jii Mofuato Jiyon
Jiei Nesutaa Jiyunia Jiyon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/680,260 external-priority patent/US4082735A/en
Priority claimed from US05/680,618 external-priority patent/US4082736A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of JPS52131526A publication Critical patent/JPS52131526A/ja
Publication of JPS638119B2 publication Critical patent/JPS638119B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP4777777A 1976-04-26 1977-04-25 New compound of immunological adjuvant and method of preparation Granted JPS52131526A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/680,260 US4082735A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US05/680,618 US4082736A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US77720477A 1977-03-14 1977-03-14

Publications (2)

Publication Number Publication Date
JPS52131526A true JPS52131526A (en) 1977-11-04
JPS638119B2 JPS638119B2 (xx) 1988-02-19

Family

ID=27418368

Family Applications (2)

Application Number Title Priority Date Filing Date
JP4777777A Granted JPS52131526A (en) 1976-04-26 1977-04-25 New compound of immunological adjuvant and method of preparation
JP1217176A Granted JPH02138290A (ja) 1976-04-26 1989-08-23 新規な免疫アジュバント化合物およびその製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1217176A Granted JPH02138290A (ja) 1976-04-26 1989-08-23 新規な免疫アジュバント化合物およびその製造方法

Country Status (8)

Country Link
JP (2) JPS52131526A (xx)
CH (1) CH636887A5 (xx)
DE (1) DE2718010A1 (xx)
ES (1) ES458197A1 (xx)
FR (1) FR2349600A1 (xx)
GB (1) GB1571133A (xx)
NL (1) NL7704555A (xx)
SE (1) SE445924B (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55102599A (en) * 1979-01-29 1980-08-05 Merck & Co Inc Immunologically active dipertidyl saccharides and manufacture
JPS56128794A (en) * 1980-02-15 1981-10-08 Ciba Geigy Ag Aldohexose derivatives, their manufacture and medicine containing them
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002677B1 (en) * 1977-12-02 1982-10-13 Takeda Chemical Industries, Ltd. Glucosamine-peptide derivatives and their pharmaceutical compositions
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
EP0013856B1 (en) * 1978-12-22 1983-03-09 ANVAR Agence Nationale de Valorisation de la Recherche New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
FR2449697A1 (fr) * 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
CA1185237A (en) * 1979-02-28 1985-04-09 Yuichi Yamamura 6-deoxyglucosamine-peptide derivatives, their production and use
FR2482957A2 (fr) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
CN108883080B (zh) * 2015-12-15 2021-12-21 巴拉特生物技术国际有限公司 胞壁酰肽衍生物化合物、其合成及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55102599A (en) * 1979-01-29 1980-08-05 Merck & Co Inc Immunologically active dipertidyl saccharides and manufacture
JPS56128794A (en) * 1980-02-15 1981-10-08 Ciba Geigy Ag Aldohexose derivatives, their manufacture and medicine containing them
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture

Also Published As

Publication number Publication date
SE7704609L (sv) 1977-10-27
DE2718010C2 (xx) 1990-11-08
JPS638119B2 (xx) 1988-02-19
JPH02138290A (ja) 1990-05-28
CH636887A5 (en) 1983-06-30
ES458197A1 (es) 1978-08-16
SE445924B (sv) 1986-07-28
GB1571133A (en) 1980-07-09
NL7704555A (nl) 1977-10-28
JPH0371440B2 (xx) 1991-11-13
FR2349600A1 (fr) 1977-11-25
DE2718010A1 (de) 1977-11-10
FR2349600B1 (xx) 1981-01-02

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