JPS52118493A - Cephalospoline derivatives and process for preparing same - Google Patents

Cephalospoline derivatives and process for preparing same

Info

Publication number
JPS52118493A
JPS52118493A JP3690677A JP3690677A JPS52118493A JP S52118493 A JPS52118493 A JP S52118493A JP 3690677 A JP3690677 A JP 3690677A JP 3690677 A JP3690677 A JP 3690677A JP S52118493 A JPS52118493 A JP S52118493A
Authority
JP
Japan
Prior art keywords
cephalospoline
derivatives
preparing same
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3690677A
Other languages
English (en)
Inventor
Buroieru Heruman
Deietaa Toroineru Uue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of JPS52118493A publication Critical patent/JPS52118493A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP3690677A 1976-03-30 1977-03-30 Cephalospoline derivatives and process for preparing same Pending JPS52118493A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/671,788 US4063019A (en) 1976-03-30 1976-03-30 [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives

Publications (1)

Publication Number Publication Date
JPS52118493A true JPS52118493A (en) 1977-10-04

Family

ID=24695885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3690677A Pending JPS52118493A (en) 1976-03-30 1977-03-30 Cephalospoline derivatives and process for preparing same

Country Status (4)

Country Link
US (2) US4063019A (ja)
JP (1) JPS52118493A (ja)
DE (1) DE2714214A1 (ja)
FR (1) FR2346356A1 (ja)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889563B2 (en) 2013-01-07 2021-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors
US11104649B2 (en) 2015-07-08 2021-08-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US11124485B2 (en) 2015-07-08 2021-09-21 Cv6 Therapeutics (Ni) Limited Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
US11168059B2 (en) 2016-11-23 2021-11-09 Cv6 Therapeutics (Ni) Limited Amino sulfonyl compounds
US11174271B2 (en) 2016-11-23 2021-11-16 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
US11198677B2 (en) 2015-07-08 2021-12-14 University Of Southern California Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
US11247984B2 (en) 2017-01-05 2022-02-15 Cv6 Therapeutics (Ni) Limited Uracil containing compounds
US11479531B2 (en) 2015-07-08 2022-10-25 University Of Southern California Deoxyuridine triphosphatase inhibitors
US11518746B2 (en) 2016-11-23 2022-12-06 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828261A1 (de) * 1978-06-28 1980-01-10 Thomae Gmbh Dr K Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GR78166B (ja) * 1981-05-04 1984-09-26 Chinoin Gyogyszer Es Vegyeszet

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3485819A (en) 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins
US3687949A (en) 1969-01-21 1972-08-29 Bristol Myers Co Synthetic cephalosporins
US3641021A (en) 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3673183A (en) 1969-11-17 1972-06-27 Squibb & Sons Inc {60 -ureidocephalosporanic acid compounds
US3708479A (en) * 1970-10-26 1973-01-02 Squibb & Sons Inc Acyloxymethyl esters of alpha-ureidocyclo-hexadie nylalkylene-cephalosporins
US3833568A (en) 1970-11-27 1974-09-03 Squibb & Sons Inc Heterocyclic ureidocephalosporins
US3855213A (en) 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
AU468437B2 (en) 1971-03-09 1976-01-15 Takeda Chemical Industries, Ltd Cephalosporin derivatives
DE2118635A1 (de) * 1971-04-17 1972-11-02 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Acylaminocephalosporansäuren und Verfahren zu ihrer Herstellung
US3821207A (en) 1971-06-21 1974-06-28 Smithkline Corp 7-heterocyclic substituted cephalosporins
BE786271A (fr) 1971-07-17 1973-01-15 Takeda Chemical Industries Ltd Cephalosporines
BE787635A (fr) 1971-08-20 1973-02-19 Takeda Chemical Industries Ltd Cephalosporines
US3796801A (en) 1971-11-04 1974-03-12 Smithkline Corp Method of combating enterobacter infections
US3887549A (en) 1971-11-19 1975-06-03 Merck & Co Inc Process for preparing 7-acylamido-7-methoxy-3-cephem-4-carboxylic acid, esters and salts
US3780033A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3843641A (en) 1971-11-29 1974-10-22 Merck & Co Inc Process for preparing penicillin and cephalosporin compounds
US3780031A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3780037A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3775410A (en) 1971-11-29 1973-11-27 B Christensen Process for preparing cephalosporin compounds
US3780034A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3792047A (en) 1971-12-07 1974-02-12 Glaxo Lab Ltd N-(7,2'-thienylacetamidoceph-3-em-3-ylmethyl)-3"or 4"-n-hydroxyloweralkylcarbamoyl-pyridinium-4-carboxylates
US3813388A (en) 1972-01-31 1974-05-28 L Crast 7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(2-methyl-1,2,3-triazole-4-yl)thiomethyl)-3-cephem-4-carboxylic acids
US3860591A (en) 1972-08-03 1975-01-14 Squibb & Sons Inc Acylthiomethyl esters of cephalosporins
US3897424A (en) 1973-07-23 1975-07-29 Lilly Co Eli Process for 7-{62 -amino-7-{60 -methoxy-cephalosporanic acid esters and related compounds
US3956288A (en) * 1973-11-07 1976-05-11 Richardson-Merrell Inc. 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives
DK130375A (ja) 1974-04-01 1975-10-02 Lilly Co Eli
US3925368A (en) * 1974-04-01 1975-12-09 Lilly Co Eli Acylureido substituted cephalosporins
JPS50130784A (ja) 1974-04-01 1975-10-16

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889563B2 (en) 2013-01-07 2021-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors
US11104649B2 (en) 2015-07-08 2021-08-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US11124485B2 (en) 2015-07-08 2021-09-21 Cv6 Therapeutics (Ni) Limited Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
US11198677B2 (en) 2015-07-08 2021-12-14 University Of Southern California Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
US11479531B2 (en) 2015-07-08 2022-10-25 University Of Southern California Deoxyuridine triphosphatase inhibitors
US11584723B2 (en) 2015-07-08 2023-02-21 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US11168059B2 (en) 2016-11-23 2021-11-09 Cv6 Therapeutics (Ni) Limited Amino sulfonyl compounds
US11174271B2 (en) 2016-11-23 2021-11-16 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
US11518746B2 (en) 2016-11-23 2022-12-06 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors
US11247984B2 (en) 2017-01-05 2022-02-15 Cv6 Therapeutics (Ni) Limited Uracil containing compounds

Also Published As

Publication number Publication date
US4063019A (en) 1977-12-13
US4093801A (en) 1978-06-06
DE2714214A1 (de) 1977-10-13
FR2346356A1 (fr) 1977-10-28

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