FR2346356A1 - Nouveaux derives de ((((2,4-dioxo-1-imidazolinyl) amino) carbonyl) amino) acetylcephalosporine - Google Patents

Nouveaux derives de ((((2,4-dioxo-1-imidazolinyl) amino) carbonyl) amino) acetylcephalosporine

Info

Publication number
FR2346356A1
FR2346356A1 FR7709302A FR7709302A FR2346356A1 FR 2346356 A1 FR2346356 A1 FR 2346356A1 FR 7709302 A FR7709302 A FR 7709302A FR 7709302 A FR7709302 A FR 7709302A FR 2346356 A1 FR2346356 A1 FR 2346356A1
Authority
FR
France
Prior art keywords
amino
acetylcephalosporine
imidazolinyl
dioxo
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7709302A
Other languages
English (en)
Inventor
Hermann Breuer
Uwe D Treuner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2346356A1 publication Critical patent/FR2346356A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/80Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
FR7709302A 1976-03-30 1977-03-29 Nouveaux derives de ((((2,4-dioxo-1-imidazolinyl) amino) carbonyl) amino) acetylcephalosporine Withdrawn FR2346356A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/671,788 US4063019A (en) 1976-03-30 1976-03-30 [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives

Publications (1)

Publication Number Publication Date
FR2346356A1 true FR2346356A1 (fr) 1977-10-28

Family

ID=24695885

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7709302A Withdrawn FR2346356A1 (fr) 1976-03-30 1977-03-29 Nouveaux derives de ((((2,4-dioxo-1-imidazolinyl) amino) carbonyl) amino) acetylcephalosporine

Country Status (4)

Country Link
US (2) US4063019A (fr)
JP (1) JPS52118493A (fr)
DE (1) DE2714214A1 (fr)
FR (1) FR2346356A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509311A1 (fr) * 1981-05-04 1983-01-14 Chinoin Gyogyszer Es Vegyeszet Derives de beta-lactame, les compositions pharmaceutiques les contenant et leur procede de preparation

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828261A1 (de) * 1978-06-28 1980-01-10 Thomae Gmbh Dr K Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP2941423B1 (fr) 2013-01-07 2021-06-09 University of Southern California Inhibiteurs de la désoxyuridine triphosphatase
WO2017006283A1 (fr) 2015-07-08 2017-01-12 Cv6 Therapeutics (Ni) Limited Inhibiteurs de désoxyuridine triphosphatase contenant une liaison cyclopropano
WO2017006270A1 (fr) 2015-07-08 2017-01-12 University Of Southern California Inhibiteurs de la désoxyuridine triphosphatase
CA2991468A1 (fr) 2015-07-08 2017-01-12 Cv6 Therapeutics (Ni) Limited Hydantoine contenant des inhibiteurs de la desoxyuridine triphosphatase
WO2017006271A1 (fr) 2015-07-08 2017-01-12 University Of Southern California Inhibiteurs de désoxyuridine triphosphatase contenant une liaison sulfonyle aminée
US10829457B2 (en) 2016-11-23 2020-11-10 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors
US11174271B2 (en) 2016-11-23 2021-11-16 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
WO2018098209A1 (fr) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Composés aminosulfonyle
WO2018128720A1 (fr) 2017-01-05 2018-07-12 Cv6 Therapeutics (Ni) Limited Composés contenant de l'uracile

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3485819A (en) 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins
US3687949A (en) 1969-01-21 1972-08-29 Bristol Myers Co Synthetic cephalosporins
US3641021A (en) 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3673183A (en) 1969-11-17 1972-06-27 Squibb & Sons Inc {60 -ureidocephalosporanic acid compounds
US3708479A (en) * 1970-10-26 1973-01-02 Squibb & Sons Inc Acyloxymethyl esters of alpha-ureidocyclo-hexadie nylalkylene-cephalosporins
US3833568A (en) 1970-11-27 1974-09-03 Squibb & Sons Inc Heterocyclic ureidocephalosporins
US3855213A (en) 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
AU468437B2 (en) 1971-03-09 1976-01-15 Takeda Chemical Industries, Ltd Cephalosporin derivatives
DE2118635A1 (de) * 1971-04-17 1972-11-02 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Acylaminocephalosporansäuren und Verfahren zu ihrer Herstellung
US3821207A (en) 1971-06-21 1974-06-28 Smithkline Corp 7-heterocyclic substituted cephalosporins
BE786271A (fr) 1971-07-17 1973-01-15 Takeda Chemical Industries Ltd Cephalosporines
BE787635A (fr) 1971-08-20 1973-02-19 Takeda Chemical Industries Ltd Cephalosporines
US3796801A (en) 1971-11-04 1974-03-12 Smithkline Corp Method of combating enterobacter infections
US3887549A (en) 1971-11-19 1975-06-03 Merck & Co Inc Process for preparing 7-acylamido-7-methoxy-3-cephem-4-carboxylic acid, esters and salts
US3780034A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3780037A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3780031A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3843641A (en) 1971-11-29 1974-10-22 Merck & Co Inc Process for preparing penicillin and cephalosporin compounds
US3775410A (en) 1971-11-29 1973-11-27 B Christensen Process for preparing cephalosporin compounds
US3780033A (en) 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3792047A (en) 1971-12-07 1974-02-12 Glaxo Lab Ltd N-(7,2'-thienylacetamidoceph-3-em-3-ylmethyl)-3"or 4"-n-hydroxyloweralkylcarbamoyl-pyridinium-4-carboxylates
US3813388A (en) 1972-01-31 1974-05-28 L Crast 7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(2-methyl-1,2,3-triazole-4-yl)thiomethyl)-3-cephem-4-carboxylic acids
US3860591A (en) 1972-08-03 1975-01-14 Squibb & Sons Inc Acylthiomethyl esters of cephalosporins
US3897424A (en) 1973-07-23 1975-07-29 Lilly Co Eli Process for 7-{62 -amino-7-{60 -methoxy-cephalosporanic acid esters and related compounds
US3956288A (en) * 1973-11-07 1976-05-11 Richardson-Merrell Inc. 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives
DK130375A (fr) 1974-04-01 1975-10-02 Lilly Co Eli
US3925368A (en) * 1974-04-01 1975-12-09 Lilly Co Eli Acylureido substituted cephalosporins
JPS50130784A (fr) 1974-04-01 1975-10-16

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509311A1 (fr) * 1981-05-04 1983-01-14 Chinoin Gyogyszer Es Vegyeszet Derives de beta-lactame, les compositions pharmaceutiques les contenant et leur procede de preparation

Also Published As

Publication number Publication date
DE2714214A1 (de) 1977-10-13
US4063019A (en) 1977-12-13
US4093801A (en) 1978-06-06
JPS52118493A (en) 1977-10-04

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Legal Events

Date Code Title Description
ST Notification of lapse