JPS5210298A - 11oxoo1hh66substituted pyrimid *1*22alpha* quinolinee 22carboxylic acid and ester thereof useful as antii tumor agent - Google Patents

11oxoo1hh66substituted pyrimid *1*22alpha* quinolinee 22carboxylic acid and ester thereof useful as antii tumor agent

Info

Publication number
JPS5210298A
JPS5210298A JP51076321A JP7632176A JPS5210298A JP S5210298 A JPS5210298 A JP S5210298A JP 51076321 A JP51076321 A JP 51076321A JP 7632176 A JP7632176 A JP 7632176A JP S5210298 A JPS5210298 A JP S5210298A
Authority
JP
Japan
Prior art keywords
quinolinee
22alpha
antii
pyrimid
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51076321A
Other languages
English (en)
Inventor
Baanaato Kadein Sooru
Furanshisu Muuaa Piitaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS5210298A publication Critical patent/JPS5210298A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP51076321A 1975-07-10 1976-06-28 11oxoo1hh66substituted pyrimid *1*22alpha* quinolinee 22carboxylic acid and ester thereof useful as antii tumor agent Pending JPS5210298A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/594,766 US4014881A (en) 1975-07-10 1975-07-10 1-Oxo-1H-6-piperidinopyrimido[1,2-a]quinoline-2-carboxylic acids and esters

Publications (1)

Publication Number Publication Date
JPS5210298A true JPS5210298A (en) 1977-01-26

Family

ID=24380322

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51076321A Pending JPS5210298A (en) 1975-07-10 1976-06-28 11oxoo1hh66substituted pyrimid *1*22alpha* quinolinee 22carboxylic acid and ester thereof useful as antii tumor agent

Country Status (19)

Country Link
US (1) US4014881A (ja)
JP (1) JPS5210298A (ja)
AR (1) AR207900A1 (ja)
BE (1) BE843660A (ja)
DD (1) DD126723A5 (ja)
DE (1) DE2628751A1 (ja)
DK (1) DK295976A (ja)
ES (1) ES449446A1 (ja)
FI (1) FI761920A (ja)
FR (1) FR2316951A1 (ja)
GB (1) GB1504683A (ja)
IE (1) IE42992B1 (ja)
IL (1) IL49810A0 (ja)
LU (1) LU75295A1 (ja)
NL (1) NL161453C (ja)
NO (1) NO762124L (ja)
PT (1) PT65294B (ja)
SE (1) SE7606761L (ja)
ZA (1) ZA763649B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. MED. CHEM *

Also Published As

Publication number Publication date
US4014881A (en) 1977-03-29
NL161453C (nl) 1980-02-15
PT65294A (en) 1976-07-01
NL161453B (nl) 1979-09-17
GB1504683A (en) 1978-03-22
IE42992B1 (en) 1980-12-03
FR2316951A1 (fr) 1977-02-04
LU75295A1 (ja) 1977-04-01
FI761920A (ja) 1977-01-11
IE42992L (en) 1977-01-10
DK295976A (da) 1977-01-11
PT65294B (en) 1977-12-13
AU1511176A (en) 1977-06-30
AR207900A1 (es) 1976-11-08
DD126723A5 (ja) 1977-08-10
NO762124L (ja) 1977-01-11
IL49810A0 (en) 1976-08-31
ZA763649B (en) 1977-05-25
DE2628751A1 (de) 1977-01-13
ES449446A1 (es) 1977-12-01
FR2316951B1 (ja) 1979-03-02
SE7606761L (sv) 1977-01-11
BE843660A (fr) 1977-01-03
NL7607103A (nl) 1977-01-12

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