JPS5035192A - - Google Patents
Info
- Publication number
- JPS5035192A JPS5035192A JP49041835A JP4183574A JPS5035192A JP S5035192 A JPS5035192 A JP S5035192A JP 49041835 A JP49041835 A JP 49041835A JP 4183574 A JP4183574 A JP 4183574A JP S5035192 A JPS5035192 A JP S5035192A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US351217A US3872122A (en) | 1973-04-16 | 1973-04-16 | 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines |
US445382A US3880855A (en) | 1973-04-16 | 1974-02-25 | 5,6-DIHYDRO-11-H-pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5035192A true JPS5035192A (ja) | 1975-04-03 |
Family
ID=26996992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP49041835A Pending JPS5035192A (ja) | 1973-04-16 | 1974-04-16 |
Country Status (7)
Country | Link |
---|---|
US (1) | US3880855A (ja) |
JP (1) | JPS5035192A (ja) |
CA (1) | CA1034125A (ja) |
DE (1) | DE2418285A1 (ja) |
FR (1) | FR2225158B1 (ja) |
GB (1) | GB1466932A (ja) |
NL (1) | NL7405012A (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009520709A (ja) * | 2005-12-22 | 2009-05-28 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | ジアゼピノン |
JP2009526849A (ja) * | 2006-02-14 | 2009-07-23 | バーテックス ファーマシューティカルズ インコーポレイテッド | タンパク質キナーゼとして有用なジヒドロジアゼピン |
US8592577B2 (en) | 2009-09-25 | 2013-11-26 | Vertex Pharmaceuticals Incorporated | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors |
US8637666B2 (en) | 2009-09-25 | 2014-01-28 | Vertex Pharmaceuticals Incorporated | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5550124A (en) * | 1991-12-10 | 1996-08-27 | University Of Southern California | Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease |
CN101420955B (zh) * | 2006-02-14 | 2013-07-17 | 沃泰克斯药物股份有限公司 | 可用作蛋白激酶抑制剂的二氢二氮杂* |
US9169246B2 (en) | 2011-09-26 | 2015-10-27 | Sanofi | Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof |
CN103012397B (zh) * | 2011-09-26 | 2017-03-01 | 赛诺菲 | 吡唑并喹啉酮衍生物、其制备方法及其治疗用途 |
EP2573073B1 (en) * | 2011-09-26 | 2014-10-22 | Sanofi | Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof |
-
1974
- 1974-02-25 US US445382A patent/US3880855A/en not_active Expired - Lifetime
- 1974-04-09 FR FR7412385A patent/FR2225158B1/fr not_active Expired
- 1974-04-11 NL NL7405012A patent/NL7405012A/xx not_active Application Discontinuation
- 1974-04-11 CA CA197,462A patent/CA1034125A/en not_active Expired
- 1974-04-16 JP JP49041835A patent/JPS5035192A/ja active Pending
- 1974-04-16 GB GB1651074A patent/GB1466932A/en not_active Expired
- 1974-04-16 DE DE2418285A patent/DE2418285A1/de not_active Withdrawn
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009520709A (ja) * | 2005-12-22 | 2009-05-28 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | ジアゼピノン |
JP2009526849A (ja) * | 2006-02-14 | 2009-07-23 | バーテックス ファーマシューティカルズ インコーポレイテッド | タンパク質キナーゼとして有用なジヒドロジアゼピン |
US8394952B2 (en) | 2006-02-14 | 2013-03-12 | Vertex Pharmaceuticals Incorporated | Dihydrodiazepines useful as inhibitors of protein kinases |
US8592577B2 (en) | 2009-09-25 | 2013-11-26 | Vertex Pharmaceuticals Incorporated | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors |
US8637666B2 (en) | 2009-09-25 | 2014-01-28 | Vertex Pharmaceuticals Incorporated | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors |
Also Published As
Publication number | Publication date |
---|---|
GB1466932A (en) | 1977-03-09 |
DE2418285A1 (de) | 1974-11-07 |
NL7405012A (ja) | 1974-10-18 |
CA1034125A (en) | 1978-07-04 |
US3880855A (en) | 1975-04-29 |
FR2225158A1 (ja) | 1974-11-08 |
FR2225158B1 (ja) | 1978-07-21 |
AU6731274A (en) | 1975-10-02 |