JPS5029574A - - Google Patents
Info
- Publication number
- JPS5029574A JPS5029574A JP49022232A JP2223274A JPS5029574A JP S5029574 A JPS5029574 A JP S5029574A JP 49022232 A JP49022232 A JP 49022232A JP 2223274 A JP2223274 A JP 2223274A JP S5029574 A JPS5029574 A JP S5029574A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB924973A GB1433774A (en) | 1973-02-26 | 1973-02-26 | Heterocyclic compounds apparatus for conveying articles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5029574A true JPS5029574A (de) | 1975-03-25 |
Family
ID=9868317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP49022232A Pending JPS5029574A (de) | 1973-02-26 | 1974-02-25 |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5029574A (de) |
| AT (1) | AT329562B (de) |
| AU (1) | AU474797B2 (de) |
| BE (1) | BE811246A (de) |
| CA (1) | CA1025856A (de) |
| CH (1) | CH602707A5 (de) |
| DE (1) | DE2407744A1 (de) |
| FR (1) | FR2218896B1 (de) |
| GB (1) | GB1433774A (de) |
| IE (1) | IE38886B1 (de) |
| LU (1) | LU69479A1 (de) |
| NL (1) | NL7402613A (de) |
| SE (1) | SE7401984L (de) |
| ZA (1) | ZA74883B (de) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005009971A1 (ja) * | 2003-07-24 | 2005-02-03 | Astellas Pharma Inc. | キノロン誘導体又はその塩 |
| JP2005535592A (ja) * | 2002-05-14 | 2005-11-24 | ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 置換されたキノロンカルボン酸、その誘導体、作用の部位、およびその使用 |
| JP2008504291A (ja) * | 2004-06-24 | 2008-02-14 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| US9670163B2 (en) | 2005-12-28 | 2017-06-06 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
| US9751839B2 (en) | 2009-03-20 | 2017-09-05 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2324304A2 (fr) * | 1975-09-22 | 1977-04-15 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| US4186201A (en) | 1977-02-07 | 1980-01-29 | Riker Laboratories, Inc. | Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds |
| US4390541A (en) | 1980-12-19 | 1983-06-28 | Lilly Industries Limited | Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease |
| FR2509728A1 (fr) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| US4377579A (en) | 1981-12-03 | 1983-03-22 | Minnesota Mining And Manufacturing Company | N-(Tetrazol-5-yl)phenazine-1-carboxamides |
| FR2537140B1 (fr) * | 1982-12-07 | 1986-07-18 | Roussel Uclaf | Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant |
| DE3875820T2 (de) * | 1987-01-20 | 1993-03-18 | Dainippon Pharmaceutical Co | Aromatische heterozyklische karbonsaeureamidabkoemmlinge, verfahren zur herstellung und arzneimittel, die diese enthalten. |
| US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| US6034100A (en) * | 1993-03-10 | 2000-03-07 | Otsuka Pharmaceutical Co., Ltd. | Method for inhibiting cytokine secretion |
| US6143760A (en) * | 1997-08-25 | 2000-11-07 | Neurogen Corporation | Substituted 4-oxo-napthyridine-3-carboxamides: GABA brain receptor ligands |
| BR9811362A (pt) * | 1997-08-25 | 2000-08-22 | Neurogen Corp | Composto |
| BR9908321A (pt) | 1998-02-26 | 2001-12-18 | Neurogen Corp | Composto |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| RU2528046C2 (ru) * | 2004-06-24 | 2014-09-10 | Вертекс Фармасьютикалз Инкорпорейтед | Модуляторы транспортеров атф-связывающей кассеты |
| EP2502912A3 (de) * | 2004-06-24 | 2013-11-06 | Vertex Pharmaceuticals Incorporated | Modulatoren von Transportern der ATP-bindenden Kassette |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| US9403802B2 (en) | 2012-03-02 | 2016-08-02 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use therefor |
| WO2014077401A1 (ja) | 2012-11-19 | 2014-05-22 | 武田薬品工業株式会社 | 含窒素複素環化合物 |
| CN105330602B (zh) * | 2015-12-07 | 2018-02-09 | 江南大学 | 一种癸氧喹酯类似物及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1383088A (en) * | 1972-07-03 | 1975-02-05 | Allen & Hanburys Ltd | Pharmacologically active quinaldamide derivatives |
-
1973
- 1973-02-26 GB GB924973A patent/GB1433774A/en not_active Expired
-
1974
- 1974-02-08 IE IE00249/74A patent/IE38886B1/xx unknown
- 1974-02-11 ZA ZA740883A patent/ZA74883B/xx unknown
- 1974-02-14 SE SE7401984A patent/SE7401984L/xx unknown
- 1974-02-14 AU AU65592/74A patent/AU474797B2/en not_active Expired
- 1974-02-18 CH CH224374A patent/CH602707A5/xx not_active IP Right Cessation
- 1974-02-18 DE DE19742407744 patent/DE2407744A1/de active Pending
- 1974-02-19 BE BE141102A patent/BE811246A/xx unknown
- 1974-02-22 LU LU69479A patent/LU69479A1/xx unknown
- 1974-02-25 JP JP49022232A patent/JPS5029574A/ja active Pending
- 1974-02-25 AT AT149974A patent/AT329562B/de not_active IP Right Cessation
- 1974-02-25 FR FR7406327A patent/FR2218896B1/fr not_active Expired
- 1974-02-26 CA CA193,476A patent/CA1025856A/en not_active Expired
- 1974-02-26 NL NL7402613A patent/NL7402613A/xx not_active Application Discontinuation
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005535592A (ja) * | 2002-05-14 | 2005-11-24 | ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 置換されたキノロンカルボン酸、その誘導体、作用の部位、およびその使用 |
| US7879878B2 (en) | 2003-07-24 | 2011-02-01 | Astellas Pharma Inc. | Quinolone derivative or salt thereof |
| WO2005009971A1 (ja) * | 2003-07-24 | 2005-02-03 | Astellas Pharma Inc. | キノロン誘導体又はその塩 |
| US7488739B2 (en) | 2003-07-24 | 2009-02-10 | Astellas Pharma Inc. | Quinolone derivative or salt thereof |
| US10662192B2 (en) | 2004-06-24 | 2020-05-26 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| JP2012062319A (ja) * | 2004-06-24 | 2012-03-29 | Vertex Pharmaceuticals Inc | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2012107069A (ja) * | 2004-06-24 | 2012-06-07 | Vertex Pharmaceuticals Inc | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2014156468A (ja) * | 2004-06-24 | 2014-08-28 | Vertex Pharmaceuticals Inc | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2008504291A (ja) * | 2004-06-24 | 2008-02-14 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| US9931334B2 (en) | 2005-12-28 | 2018-04-03 | Vertex Pharmaceuticals Incorporated | Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US10537565B2 (en) | 2005-12-28 | 2020-01-21 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US9670163B2 (en) | 2005-12-28 | 2017-06-06 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US11291662B2 (en) | 2005-12-28 | 2022-04-05 | Vertex Pharmaceuticals Incorporated | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US11564916B2 (en) | 2008-08-13 | 2023-01-31 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US9751839B2 (en) | 2009-03-20 | 2017-09-05 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US11147770B2 (en) | 2012-02-27 | 2021-10-19 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US11752106B2 (en) | 2012-02-27 | 2023-09-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1025856A (en) | 1978-02-07 |
| DE2407744A1 (de) | 1974-08-29 |
| GB1433774A (en) | 1976-04-28 |
| FR2218896B1 (de) | 1977-09-09 |
| ATA149974A (de) | 1975-08-15 |
| AU474797B2 (en) | 1976-08-05 |
| IE38886B1 (en) | 1978-06-21 |
| AU6559274A (en) | 1975-08-14 |
| SE7401984L (de) | 1974-08-27 |
| AT329562B (de) | 1976-05-25 |
| ZA74883B (en) | 1974-12-24 |
| LU69479A1 (de) | 1975-05-21 |
| NL7402613A (de) | 1974-08-28 |
| BE811246A (fr) | 1974-08-19 |
| IE38886L (en) | 1974-08-26 |
| CH602707A5 (de) | 1978-07-31 |
| FR2218896A1 (de) | 1974-09-20 |