JPS4924669B1 - - Google Patents
Info
- Publication number
- JPS4924669B1 JPS4924669B1 JP42043453A JP4345367A JPS4924669B1 JP S4924669 B1 JPS4924669 B1 JP S4924669B1 JP 42043453 A JP42043453 A JP 42043453A JP 4345367 A JP4345367 A JP 4345367A JP S4924669 B1 JPS4924669 B1 JP S4924669B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/842—Clostridium
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56370266A | 1966-07-08 | 1966-07-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS4924669B1 true JPS4924669B1 (en) | 1974-06-25 |
Family
ID=24251557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP42043453A Pending JPS4924669B1 (en) | 1966-07-08 | 1967-07-07 |
Country Status (5)
Country | Link |
---|---|
US (1) | US3705083A (en) |
JP (1) | JPS4924669B1 (en) |
BR (1) | BR6791131D0 (en) |
DE (1) | DE1642578C3 (en) |
GB (1) | GB1192937A (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2216992A1 (en) * | 1973-02-12 | 1974-09-06 | Anvar | Low MW, purified collagenase prepn - by ion-exchange chromatography of enzyme from first-stage larvae of hypoderma spp. |
US4524065A (en) * | 1983-08-04 | 1985-06-18 | Bio-Specifics N.V. | Method for the prevention and treatment of scars with enzymes |
JPS60188066A (en) * | 1984-03-09 | 1985-09-25 | Akira Endo | Novel collagenase discolysin and its preparation |
US5177017A (en) * | 1990-03-22 | 1993-01-05 | Trigen, Inc. | Molecular cloning of the genes responsible for collagenase production from Clostridium histolyticum |
CA2047306A1 (en) * | 1990-07-23 | 1992-01-24 | Milan Holjevac | Mutant bacterium clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase |
US5173295A (en) * | 1990-10-05 | 1992-12-22 | Advance Biofactures Of Curacao, N.V. | Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor |
US5393792A (en) * | 1991-11-20 | 1995-02-28 | Advance Biofactures Of Curacao, N.V. | High dosage topical forms of collagenase |
US5332503A (en) * | 1993-04-16 | 1994-07-26 | Baxter International Inc. | Process for purifying collagenase |
JP3028852B2 (en) * | 1994-06-24 | 2000-04-04 | ロシュ ダイアグノスティックス コーポレーション | Purified mixture of collagenase and two other proteases obtained from Histolyticus |
US5851522A (en) * | 1995-06-07 | 1998-12-22 | Trustees Of Tufts College | Enhancing keratinocyte migration |
US5989888A (en) * | 1996-01-24 | 1999-11-23 | Roche Diagnostics Corporation | Purified mixture of collagenase I, collagenase II and two other proteases |
US5830741A (en) * | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
US8323642B2 (en) * | 2006-12-13 | 2012-12-04 | Depuy Mitek, Inc. | Tissue fusion method using collagenase for repair of soft tissue |
US10071143B1 (en) | 2007-05-03 | 2018-09-11 | The Research Foundation For The State University Of New York | Methods for non-surgical treatment of carpal tunnel syndrome |
US20100159564A1 (en) * | 2007-11-30 | 2010-06-24 | Dwulet Francis E | Protease resistant recombinant bacterial collagenases |
AU2010328269B2 (en) | 2009-12-08 | 2014-07-10 | Smith & Nephew Orthopaedics Ag | Enzymatic wound debriding compositions with enhanced enzymatic activity |
WO2014066622A2 (en) | 2012-10-24 | 2014-05-01 | The Research Foundation For The State University Of New York | Use of collagenase to treat glaucoma |
WO2016094675A1 (en) | 2014-12-12 | 2016-06-16 | Smith & Nephew, Inc. | Use of clostridium histolyticum protease mixture in promoting wound healing |
CN110199016B (en) | 2016-11-17 | 2024-08-16 | 艾欧凡斯生物治疗公司 | Residual tumor infiltrating lymphocytes and methods of making and using the same |
US20190192724A1 (en) * | 2017-12-12 | 2019-06-27 | Bio Med Sciences, Inc. | Debriding wound dressing, process of manufacture and useful articles thereof |
-
1966
- 1966-07-08 US US563702A patent/US3705083A/en not_active Expired - Lifetime
-
1967
- 1967-06-26 GB GB29324/67A patent/GB1192937A/en not_active Expired
- 1967-06-29 DE DE1642578A patent/DE1642578C3/en not_active Expired
- 1967-07-07 BR BR191131/67A patent/BR6791131D0/en unknown
- 1967-07-07 JP JP42043453A patent/JPS4924669B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US3705083A (en) | 1972-12-05 |
GB1192937A (en) | 1970-05-28 |
DE1642578B2 (en) | 1974-02-14 |
DE1642578C3 (en) | 1974-09-19 |
BR6791131D0 (en) | 1973-05-10 |
DE1642578A1 (en) | 1972-03-09 |