|
US6339173B1
(en)
*
|
1996-07-22 |
2002-01-15 |
Promega Biosciences, Inc. |
Amide-based cationic lipids
|
|
FR2760193B1
(fr)
*
|
1997-02-28 |
1999-05-28 |
Transgene Sa |
Lipides et complexes de lipides cationiques et de substances actives, notamment pour la transfection de cellules
|
|
US5877220A
(en)
*
|
1997-03-06 |
1999-03-02 |
Genta, Incorporated |
Amide-based oligomeric cationic lipids
|
|
US6034135A
(en)
*
|
1997-03-06 |
2000-03-07 |
Promega Biosciences, Inc. |
Dimeric cationic lipids
|
|
US6395713B1
(en)
*
|
1997-07-23 |
2002-05-28 |
Ribozyme Pharmaceuticals, Inc. |
Compositions for the delivery of negatively charged molecules
|
|
CA2299429C
(en)
*
|
1997-08-13 |
2010-04-20 |
Biontex Laboratories Gmbh |
New lipopolyamines,their preparation and the use thereof
|
|
GB9914045D0
(en)
|
1999-06-16 |
1999-08-18 |
Smithkline Beecham Plc |
Novel compounds
|
|
CA2395636A1
(en)
*
|
1999-12-30 |
2001-07-12 |
Novartis Ag |
Novel colloid synthetic vectors for gene therapy
|
|
US7102024B1
(en)
|
2000-08-01 |
2006-09-05 |
Schwartz David A |
Functional biopolymer modification reagents and uses thereof
|
|
US6686461B1
(en)
|
2000-03-22 |
2004-02-03 |
Solulink Bioscience, Inc. |
Triphosphate oligonucleotide modification reagents and uses thereof
|
|
US6800728B2
(en)
|
2000-03-22 |
2004-10-05 |
Solulink Biosciences, Inc. |
Hydrazine-based and carbonyl-based bifunctional crosslinking reagents
|
|
US7294511B2
(en)
*
|
2001-03-22 |
2007-11-13 |
Chromos Molecular Systems, Inc. |
Methods for delivering nucleic acid molecules into cells and assessment thereof
|
|
DE10117043A1
(de)
*
|
2001-04-05 |
2002-11-07 |
Gerhard Puetz |
Verfahren zur Eliminierung von potentiell toxischen und/oder schädlichen Stoffen
|
|
US20070141724A1
(en)
*
|
2003-07-29 |
2007-06-21 |
Schmidt Jurgen G |
Solid phase immobilized trifunctional linker
|
|
EP1664316B1
(en)
|
2003-09-15 |
2012-08-29 |
Protiva Biotherapeutics Inc. |
Polyethyleneglycol-modified lipid compounds and uses thereof
|
|
US7158353B2
(en)
*
|
2003-11-06 |
2007-01-02 |
Seagate Technology Llc |
Magnetoresistive sensor having specular sidewall layers
|
|
US7142948B2
(en)
|
2004-01-07 |
2006-11-28 |
Honeywell International Inc. |
Controller interface with dynamic schedule display
|
|
WO2006069782A2
(en)
|
2004-12-27 |
2006-07-06 |
Silence Therapeutics Ag. |
Lipid complexes coated with peg and their use
|
|
MXPA06012722A
(es)
|
2004-05-05 |
2007-02-14 |
Atugen Ag |
Lipidos, complejos de lipido y su uso.
|
|
CA2569664C
(en)
|
2004-06-07 |
2013-07-16 |
Protiva Biotherapeutics, Inc. |
Lipid encapsulated interfering rna
|
|
CA2587411A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Protiva Biotherapeutics, Inc. |
Sirna silencing of apolipoprotein b
|
|
CN101346393B
(zh)
|
2005-11-02 |
2015-07-22 |
普洛体维生物治疗公司 |
修饰的siRNA分子及其应用
|
|
KR101670085B1
(ko)
|
2006-07-21 |
2016-10-28 |
사일런스 테라퓨틱스 게엠베하 |
단백질 키나아제 3의 발현을 억제하기 위한 수단
|
|
AU2006350707A1
(en)
*
|
2006-11-08 |
2008-05-15 |
Chongxi Yu |
Transdermal delivery systems of peptides and related compounds
|
|
ES2535419T3
(es)
*
|
2007-12-27 |
2015-05-11 |
Protiva Biotherapeutics Inc. |
Silenciamiento de expresión de quinasa tipo polo usando ARN interferente
|
|
WO2009086558A1
(en)
*
|
2008-01-02 |
2009-07-09 |
Tekmira Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
|
CA2721333C
(en)
|
2008-04-15 |
2020-12-01 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
|
CA2740000C
(en)
|
2008-10-09 |
2017-12-12 |
Tekmira Pharmaceuticals Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
|
US9023820B2
(en)
|
2009-01-26 |
2015-05-05 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing apolipoprotein C-III expression
|
|
PL2427475T3
(pl)
|
2009-05-08 |
2021-07-19 |
Techfields Biochem Co., Ltd. |
Kompozycje proleku o wysokim przenikaniu peptydów i związków powiązanych z peptydami
|
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
|
US9018187B2
(en)
|
2009-07-01 |
2015-04-28 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
|
WO2011000107A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for delivery of therapeutic agents to solid tumors
|
|
US8716464B2
(en)
|
2009-07-20 |
2014-05-06 |
Thomas W. Geisbert |
Compositions and methods for silencing Ebola virus gene expression
|
|
US8455455B1
(en)
|
2010-03-31 |
2013-06-04 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing genes involved in hemorrhagic fever
|
|
US9006417B2
(en)
|
2010-06-30 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
|
CN103380113B
(zh)
*
|
2010-11-15 |
2018-03-30 |
生命科技公司 |
含胺的转染试剂及其制备和使用方法
|
|
CN107266391B
(zh)
|
2011-10-18 |
2020-04-17 |
迪克纳制药公司 |
胺阳离子脂质及其用途
|
|
US9035039B2
(en)
|
2011-12-22 |
2015-05-19 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing SMAD4
|
|
JP5970439B2
(ja)
*
|
2013-09-20 |
2016-08-17 |
チョンシー ユー |
ペプチド及び関連化合物の経皮送達システム
|
|
HUE060907T2
(hu)
|
2014-06-25 |
2023-04-28 |
Acuitas Therapeutics Inc |
Új lipidek és lipid nanorészecske formulációk nukleinsavak bevitelére
|
|
AU2016253972B2
(en)
|
2015-04-27 |
2020-01-02 |
Acuitas Therapeutics Inc. |
Nucleoside-modified RNA for inducing an adaptive immune response
|
|
PT3313829T
(pt)
|
2015-06-29 |
2024-07-08 |
Acuitas Therapeutics Inc |
Formulações de lípidos e de nanopartículas lipídicas para a administração de ácidos nucleicos
|
|
HRP20230209T1
(hr)
|
2015-10-28 |
2023-04-14 |
Acuitas Therapeutics Inc. |
Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
|
|
EP3419986B1
(de)
*
|
2016-02-22 |
2025-11-05 |
Evonik Operations GmbH |
Rhamnolipidamide zur haarduftstoff-retention
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
CA3049991A1
(en)
|
2017-01-11 |
2018-07-19 |
The Trustees Of The University Of Pennsylvania |
Nucleoside-modified rna for inducing an immune response against zika virus
|
|
WO2018191657A1
(en)
|
2017-04-13 |
2018-10-18 |
Acuitas Therapeutics, Inc. |
Lipids for delivery of active agents
|
|
CN110799492B
(zh)
|
2017-04-28 |
2023-06-27 |
爱康泰生治疗公司 |
用于递送核酸的新型羰基脂质和脂质纳米颗粒制剂
|
|
EP4295895A3
(en)
|
2017-05-11 |
2024-03-27 |
Tc1 Llc |
Thermal interconnect for implantable blood pump
|
|
CA3073020A1
(en)
|
2017-08-16 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
WO2019036028A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
|
|
WO2019036030A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS
|
|
EP4501322A3
(en)
|
2017-08-17 |
2025-04-16 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
IL281615B2
(en)
|
2018-09-21 |
2026-01-01 |
Acuitas Therapeutics Inc |
Systems and methods for producing lipid nanoparticles and liposomes
|
|
CA3116576A1
(en)
*
|
2018-10-18 |
2020-04-23 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
PT3908568T
(pt)
|
2019-01-11 |
2024-09-30 |
Acuitas Therapeutics Inc |
Lípidos para a administração de agentes ativos por nanopartículas lipídicas
|
|
ES3054438T3
(en)
|
2020-07-16 |
2026-02-03 |
Acuitas Therapeutics Inc |
Cationic lipids for use in lipid nanoparticles
|
|
WO2022115645A1
(en)
|
2020-11-25 |
2022-06-02 |
Akagera Medicines, Inc. |
Lipid nanoparticles for delivery of nucleic acids, and related methods of use
|
|
CA3242402A1
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
CA3256897A1
(en)
|
2022-05-25 |
2023-11-30 |
Akagera Medicines, Inc. |
Lipid nanoparticles for the administration of nucleic acids and their methods of use
|
|
CN120737001A
(zh)
*
|
2022-06-02 |
2025-10-03 |
厦门赛诺邦格生物科技股份有限公司 |
一种氨基酸阳离子脂质
|
|
CN117460711B
(zh)
*
|
2022-06-02 |
2025-07-08 |
厦门赛诺邦格生物科技股份有限公司 |
一种含有不饱和键的氨基酸阳离子脂质
|
|
CN119630438A
(zh)
*
|
2022-08-12 |
2025-03-14 |
五眼高新技术株式会社 |
溶剂中抗原回收系统及溶剂中抗原回收方法
|
|
US20240261223A1
(en)
*
|
2022-12-27 |
2024-08-08 |
Sunvax Mrna Therapeutics |
Modular lipid compounds and two- to three-component lipid nanoparticle compositions
|
|
WO2025001700A1
(zh)
*
|
2023-06-30 |
2025-01-02 |
厦门赛诺邦格生物科技股份有限公司 |
一种含有两个叔胺基团的阳离子脂质及其应用
|