JPH11169099A - Crude medicine composition or adding to feed for farmed fishes - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a crude medicine composition for adding to feed for farmed fishes in order to promote growth of marine fishes and freshwater fishes. SOLUTION: This crude medicine composition contains Crataegi fructus, Glycyrrhizae Radix, Aurantii Fructus Immaturus, Platycodi radix, unripe Citri leiocarpae exocarpium, Saussureae radix, cyperi rhizoma, Pogosgtemi herba, Fructus hordei germinatus, Massa medicata fermentat, Zizyphi spinosi semen, Amomi semen and Alpiniae oxyphyllae semen as crude medicine components and preferably further contains Amorirotundi fructus, Alpiniae katsumadaii semen, lonicerae flos, Acanthopanax spinosum, Forsythiae fructus, schizonepetae herba, root of Angelica Dahurica, Dioscoreae rhizoma, Nelumbinis semen, Citri leiocarpae exocarpium, Magnoliae Cortex or a mixture thereof as crude medicine components. Survival rate of farmed fishes is increased and growth rate is increased and efficiency of feed is enhanced and environmental pollution can be prevented by adding the crude medicine composition to the feed and giving the composition to farmed fishes. Further, since Chinese crude medicines whose safeties are confirmed are used as raw materials, the medicines are harmless to fishes and human bodies which take it.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION The present invention relates to a method of cultivating marine or freshwater fish which is added to a feed and administered to the fish, thereby promoting the growth of the fish and increasing the efficiency of the feed to reduce excretion. The present invention relates to a biopharmaceutical composition to be added to a fish feed which can minimize environmental pollution and is harmless to fish and the human body.

[0002]

2. Description of the Related Art The aquaculture industry has recently attracted attention because fishery resources have been gradually depleted due to indiscriminate capture and the like. However, in the case of marine fish farming, the productivity is greatly threatened by the pollution of coastal fishing grounds themselves and the damage of red tides. Water source pollution has become a problem. In view of the friction between the aquaculture industry and the environment, it is difficult to significantly increase production without the development of new aquaculture and fishing grounds.

[0003] However, at present, it is difficult to develop a new aquaculture ground, so it is necessary to develop a method for promoting the growth of aquacultured fish and increasing the productivity. Conventionally, as a method for promoting the growth of cultured fish, a method of adding animal growth hormone to fish feed and administering it has been performed. However, this conventional method has the problems of harmful effects on the human body when the fish to which hormones are administered is ingested by the human body, and the sea and rivers are polluted by feed residues containing hormones that are not taken by the fish and left. Problem.

[0004]

Accordingly, the efficiency of the feed given to the cultured fish is increased to promote the growth of the target fish, and the environmental pollution is reduced by reducing the excrement discharged into the sea or river. It has been desired to develop a method that is harmless to fish and the human body.

Accordingly, the present invention has been made in view of the above-mentioned circumstances, and an object of the present invention is to enhance the digestion and absorption functions of fish by adding them to the feed of farmed fish, thereby minimizing excretion. The present invention provides a fish feed additive composition that can reduce environmental pollution and promote the growth of fish by improving the productivity and improve productivity, and is harmless to fish and the human body that consumes the fish. It is in.

[0006] Another object of the present invention is to provide a method for promoting the growth of cultured fish using the composition as described above.

[0007]

In order to achieve the above object, the feed additive composition for promoting the growth of cultured fish according to the present invention is characterized in that it contains a crude drug powder.

Further, the method for promoting the growth of cultured fish according to the present invention comprises adding a feed additive composition containing a crude drug powder to a feed and administering to the cultured fish.

The crude drugs used in the feed additive composition of the present invention include:

[Table 1] Including here

[Table 2] Or it is desirable that these mixtures be further added.

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION The present invention relates to a crude drug which has been used for a long time and has been confirmed to be safe in order to promote the growth of cultured fish and to reduce the excretion of cultured fish which causes water pollution. It is characterized in that it is used by adding a kind of Chinese herbal nutrient composition as a component to a feed for fish culture. As crude drugs to be contained in the crude drug composition for feed addition of the present invention, Yamakoko, licorice, citrus, bellflower, green skin, wood incense, incense, jujube, cuckoo, malt, cinnamon, cinnamon, magnolia, sandin, sandalwood, Japanese squid, Mashiko Hitoshi, gold and silver flowers, quince, forsythia,
There are thorns, juniper, mountain medicine and lotus meat. Looking at the physiological activities and functions of these crude drugs, Yamako plays a role as a digestive agent in animal feed, and licorice harmonizes the medicinal properties and plays a detoxifying effect. Kobushi enhances activity, acid soybeans stabilize nerves and relieve stress, and sand seeds, sandalwood, sourdzuk, masutoshi, malt, singapore, cuckoo, chenchi and ssangpak promote digestion, and gold and silver Flowers, sycamore, forsythia, thorns, and juniper enhance skin resistance and prevent skin diseases, and mountain herbs and lotus meat provide elasticity to muscles.

[0011] The crude drug composition used as a feed additive for cultured fish of the present invention is preferably (a) Yamashiko, licorice, citrus, bellflower, green peel, wood incense, kazushi, cuckoo, malt, sage, acid soybean In addition to the component (a), more preferably, zinnia sylvestris, sorghum, gold and silver flowers, gokakin, consecutive forsythia, forsythia, juniper, mountain herbs, lotus meat, cinnabar, thick Includes magnolia or mixtures thereof.
In particular, zambia, sorghum, gold and silver flowers, quince, forsythia, forsythia, juniper and zinnia are further added in addition to the component (a), or zambia, azalea, gold and silver in addition to the component (a). Flowers, quince, forsythia, thorn garbage, juniper, herbal medicine and lotus meat, or, in addition to the above-mentioned component (a), hen skin, magnolia, herbal medicine and lotus meat. Are preferred.

A particularly preferred crude drug composition of the present invention is formulated as follows.

[0013]

[Table 3] (1) Yamako: 24 parts by weight Licorice: 20 parts by weight Citrus, bellflower, green skin, wood incense, incense and cuckoo: 18 parts by weight Malt, cinnamon and acid jujube: 12 parts by weight Sunin, sandalwood , Sou-zuku, Masuchihito, Goka-ki, Liquorice, and Forage: 8 parts by weight Gold and silver flower: 10 parts by weight Juniper: 6 parts by weight (2) Yamako: 24 parts by weight Licorice: 20 parts by weight Citrus, bellflower, green skin, wood Incense, Kazushi, Cuckoo, Yamayaku, Lotus root meat: 18 parts by weight Malt, sagek, acid jujube: 12 parts by weight Sunin, zyakuzuku, sozuku, Echijin, gold and silver flowers: 8 parts by weight Forsythia, thorns: 6 parts by weight Juniper: 5 parts by weight (3) Yamabiko, Kiko shell, bellflower, green skin, incense, incense, cuckoo, malt, cinnamon, acid soybean, sand, cinnabar, thick skin, machujin : 3 parts by weight each Yamayaku, lotus meat, licorice: 4 parts by weight each (1 The composition of (2) has the effect of preventing skin diseases, which are particularly likely to occur in the flash larvae, and also has the effect of enhancing digestion and making the fish healthy. The composition of (2) is particularly useful for digesting carnivorous fish. The composition of (3) enhances the digestion of fish eating a plant feed and stabilizes nerves to increase the growth rate and increase the feed coefficient. Play a role to improve.

The crude drug composition as a feed additive for cultured fish according to the present invention is mixed with fish at a ratio of 1 to 10 g / kg (ie, 0.1 to 1.0% by weight) per 1 kg of fish feed. It is preferred to administer.

[0015]

The present invention will be described in more detail with reference to the following examples. In addition, the following Examples are only illustrations of the present invention,
The present invention is not limited to this.

[0016]

[Table 4] (1) Production of crude drug composition of formula (1) Yamako: 24 g Licorice: 20 g Citrus, bellflower, green skin, incense, Katsuki, cuckoo: 18 g each Malt, cinnamon, acid soybean: 12 g each , Sandalwood, sorghum, masuhito, five rinds, forsythia, forage: 8 g each Gold and silver flowers: 10 g juniper: 6 g Of the above crude drugs, Yamako, Satsumajin, Sandin, Zakakuzuku, Souzuku and Machijin have darker surfaces. And the remaining crude drug was dried so that it could be easily crushed, mixed and then finely crushed with a grinder to produce.

[0017]

[Table 5] (2) Production of crude drug composition of formula (2) Yamako: 24 g Licorice: 20 g Citrus, bellflower, green skin, wood incense, Katsuki, cuckoo, mountain medicine, lotus meat: 18 g each Malt, syringus, soju Jin: 12 g each Sun sand, sandalwood, soybean, Echijin, gold and silver flowers: 8 g each Sesame peel, forsythia, forage: 6 g each Jacuzzi: 5 g Among the above crude drugs, Yamashiko, acid soju, sandin, sandalwood, soybeans and profit Tomohito was roasted so that the surface became darker, and the remaining crude drug was dried so that it could be easily crushed, mixed, and then finely crushed with a grinder.

[0018]

[Table 6] (3) Production of crude drug composition of formula (3) Yamako, Kiko shell, bellflower, green skin, wood incense, incense, cuckoo, malt, cinnamon, acid soybean, sand hull, cinnabar, thick skin, macho Jin: 3g each Yamayaku, lotus meat, licorice: 4g each Among the above crude drugs, Yamadoko, Satsumajin, Sandin and Echijin are roasted so that the surface becomes darker, and the remaining crude drugs are dried and crushed so as to be easily crushed. After being combined, they were finely pulverized with a grinder to produce.

1. Effect test on freshwater fish (A) Comparison of growth of Nile tilapia larvae by addition amount of crude drug composition In order to evaluate the appropriate dose of crude drug composition of the present invention in freshwater fish culture, Nile tilapia (Oreochromis niloti)
cus).

[0020] Nile tilapia hatching larvae produced through artificial hatching are separated into five groups, and five small cages are placed in a 150-liter water tank provided with a filtration tank for up to three weeks after the first feeding. Forty-five animals were provided, and from 3 weeks to the seventh week, they were separately housed and cultured in a 150-liter square glass water tank to which circulating-filtered breeding water was supplied. During the experimental period, the water temperature was kept at 28 ± 2 ° C., and the dissolved oxygen was kept at 4.7 to 6.8 mg / L.

The experimental feed was a commercially available feed for eel (crude protein 55.
0% or more, crude fat 3.0% or more, crude fiber 3.0% or more,
Crude ash content 19.0% or more, Ca 2.0% or more, P2.7%
As described above, the crude drug composition (3) produced as described above was added to the nutritional supplement and the other 7.8% or more) in an amount of 0% (control group), respectively.
The solidified feed added at the ratios of 0.25%, 0.5%, 1.0% and 2.0% was administered 6 to 9 times a day until satiety.

At the beginning of the experiment and at 3, 5 and 7 weeks, the fish were weighed to the nearest 1 mg, and the total length of the fish was measured to 1/100 mm using a Vernier caliper. Growth rate after fish measurement (percent weight gain), daily growth rate (spe
cific growth rate, feed coefficienc
y), obesity level (condition factor) is investigated, and One-way ANO
VA was performed to test the significance of the experimental results.

Table I shows the results of the experiment. As can be seen from Table I, the growth of the control group and the herbal composition-treated group was determined in Experiment 3
A significant difference appeared at week (p <0.05), and the 2.0% treatment group showed lower growth, growth rate and daily growth rate than the other treatment groups (p <0.05). .

According to the results of the experiment at week 7, the growth rate was highest in the group treated with the crude drug composition 0.5% (p <0.05),
The feed factor was highest in the 0.25% treatment group and the obesity level was highest in the 1.0% treatment group.

[0025]

[Table 7] (A) Comparison of growth of Nile tilapia bred fish by addition of crude drug composition Nile tilapia weighing 200 to 250 g is divided into two groups and stored in a 5-ton capacity concrete circular water tank to which circulating filtered breeding water is supplied. And bred for 30 days.
During the experimental period, the water temperature was maintained at 27.0-30.0 ° C and dissolved oxygen at 2.0-4.5 mg / L. When an individual died in each experimental group, the animal was replaced with one having the same fish weight, and the experiment was continued.

The experimental feed was a commercially available tilapia feed (crude protein 34.0% or more, crude fat 4.0% or more, crude fiber 4.0%).
Above, crude ash content 18.0% or more, Ca 10% or more, P1.
The crude drug composition (3) produced as described above is adsorbed to 0% (control group) and 0.3% (treated group) on 8% or more, nutritional supplements and other 2.8% or more, respectively. And was fed four times a day until full.

The body weight of the fish was measured twice at 15-day intervals after the start of the experiment, and the growth rate, daily growth rate, and feed coefficient were measured. In addition, six animals were randomly extracted from each experimental aquarium and subjected to body composition analysis for muscles and liver, and AOAC (19
According to the method of 90), the water content was analyzed by an atmospheric pressure drying method, the crude protein was analyzed by Kjeldahl nitrogen determination method, the crude fat was analyzed by Soxhlet extraction method, and the crude ash was analyzed by direct incineration method. Student's t-test was performed to test the significance of the experimental results.

Table II shows the results of growth comparison between the control group and the group treated with 0.3% of the crude drug composition. As can be seen from Table II, the group treated with the crude drug composition showed significantly faster growth than the control group (p <0.05), and the growth rate, the daily growth rate, and the feed coefficient were also higher than those of the control group. A significant difference was shown (p <
0.05).

Table III shows the results of body growth comparison between the control group and the group treated with 0.3% of the crude drug composition. As can be seen from Table III, there was no significant difference between the control group and the herbal composition-treated group in the results of analysis of the back muscle water, protein, fat and ash (p.
> 0.05), and the liver analysis results showed the same tendency. Therefore, it is considered that there is no change in the components of the tilapia fish due to the addition of the crude drug composition of the present invention.

[0030]

[Table 8]

[Table 9] (C) Growth comparison of adult Nile tilapia fish by addition of crude drug composition Two adult Nile tilapia fish weighing 498.0 to 510.0 g were placed in a 58-ton concrete round water tank supplied with circulating filtered breeding water. 17 in groups
They were bred for 5 days. During the experimental period, the water temperature was 23.0-2.
At 5.0 ° C., the dissolved oxygen was kept at 2.5 to 4.0 mg / liter.

The experimental feed was prepared by mixing 0% (control group) and 0.3% (treatment group) of the crude drug composition (3) prepared above as described above with a commercially available tilapia feed, followed by automatic demand feeder (automatic demand feeder). feeder).

After completion of the experiment, the weight of fish
The growth rate, daily growth rate and feed coefficient were measured, and one-way AN
OVA was performed to test the significance of the experimental results.

The mortality of each experimental group was 1.52 during the experimental period.
~ 2.48%, and the herbal composition treated group (1.79 ±
(0.23%) and the control group (2.16 ± 0.35%) were not significantly different (Student's t-test: p> 0.
05). Table IV shows the results of the growth experiments of the herbal composition-treated group and the control group. The crude drug composition-treated group showed significantly higher results in total fish body weight, growth rate and daily growth rate than the control group (p <0.05), and the food factor was significantly higher than the control group. It was low.

[0034]

[Table 10] 2. Effect test on marine fish (a) Comparison of growth of larvae of larvae by addition of crude drug composition To evaluate the appropriate dose of the herbal composition of the present invention in marine fish culture,
us) fry.

The fry of the Japanese rainbow trout was divided into four groups, and the experimental feed (48.7% crude protein) was used for 6 weeks after starting to eat the first feed.
Above, crude fat 12.6% or more, crude ash content 16.6% or more,
Nutrients and other 12% or more) with the crude drug composition (1) produced as described above at 0% (control group) and 0.15%, respectively.
%, 0.30% and 0.60% of the feed were fed until full, and were bred under normal inoculation conditions.

The average fish weight, daily growth rate, dietary index and obesity level of each group were measured at the beginning of the experiment and at two-week intervals thereafter, and the results are shown in Table V. As shown in Table V, the group treated with the crude drug composition showed a significant difference from the control group on the fourth week of the experiment.
It was found that the daily growth rate, the dietary coefficient and the degree of obesity were generally desirable.

As a result of examining the survival rate of each group, 86.11 ± 4.37% in the control group, 92.78 ± 2.08% in the group treated with 0.15% of the crude drug composition, 99.44 ± 0.79% in the 0.30% treatment group,
98.89 ± 0.79 in crude drug composition 0.60% treatment group
%, The group treated with the crude drug composition was significantly higher than the control group, and the survival rate was particularly highest in the group treated with the crude drug composition 0.30%.

[0038]

[Table 11] (A) Comparison of the growth of litter by adding the crude drug composition The fry of the litter were divided into two groups, and the experimental diet (crude protein 31.6% or more, crude fat 5.0%) for 48 weeks after starting to eat the first diet As described above, the crude drug composition (2) produced as described above was 0% (control group) and 0.1% in water (35.2%).
The animals were bred under normal flashing culture conditions while being added at a ratio of 30% (treatment group) and fed until they became full.

For each group, the average fish weight, daily growth rate, dietary index, and obesity were measured at the beginning of the experiment and at four-week intervals thereafter. The results at the start of the experiment, after 24 and 48 weeks, are shown in Table VI. In addition, as a result of examining the survival rate of each group, it was 80.89 ± 4.53% in the control group, and 92.89 ± in the group treated with the crude drug composition 0.30%.
1.66%, which was significantly higher in the herbal composition-treated group.

[0040]

[Table 12] 3. Meat Quality Evaluation Test A flesh evaluation test was performed on the bred bred on the feed to which the crude drug composition of the present invention was added by measuring sensory tests, physical properties, taste components, and the like.

Methods such as gold (Kim, DS, YBMoon, CHJe
ong, BSKim and YDLee, Production of All-Female
Diploid and Triploid Populations in Paralichthys o
livaceus, J. Aquaculture, 7: 159-164 (199
4) To all females produced by (1), mixed feed (frozen
Horse mackerel and commercial bind meal are mixed at 50% each) and the crude drug composition (2) produced as described above is bred on a feed added at a ratio of 0% (control group) and 0.3% (treatment group). did. After the sample fish were killed immediately by medullary shooting, they were turned into three spores and immediately used only for the spine.

(A) Sensory test A taste test and a discrimination test were performed on 15 trained students of the Department of Aquaculture at Pukei University. The taste test is performed on the appearance, smell, texture, taste, and overall preference after cutting the sample to a thickness of about 5 mm. Was evaluated. The discrimination test is from +3 to -3 for 9 items such as transparency, gloss, smell, hardness, and elasticity.
It was evaluated on a scale.

FIG. 1 is a graph showing the results of a sensory test on fish meat of a treated group and a control group which were bred by adding the crude drug composition of the present invention to feed. According to FIG. 1, the fish meat of the treatment group bred with the feed containing the crude drug composition was preferred in all the items of the taste test, and significant in all items except the transparency, smell and adhesion in the discrimination test. The difference appeared. That is,
The meat quality of the treated group was particularly superior in gloss, hardness and elasticity compared to the control group, and it was evaluated that the wood grain was slightly damp and fine, indicating that the palatability and the appetite taste were significantly affected by the overall preference. .

(A) Measurement of Physical Properties The hardness, elasticity and cohesiveness of a sample accurately cut to (15 × 15 × 9) mm were evaluated using a Sun Rheometer compact-100. Table VII shows the results of 5 measurements per sample for 5 animals per group. As shown in Table VII, the treated group bred with the crude drug composition-added feed had significantly higher hardness, elasticity and cohesiveness than the control group, and had a strong meat quality.

[0045]

[Table 13] (C) Measurement of taste components About 10 g of a sample was homogenized, and the method of Moore (Moore, S., Bio
After extracting the free amino acids by l.Chem..238, 235 (1963)), the free amino acids were analyzed by fluorescence analysis by the OPA method under biological fluid analysis conditions using an Intelligent HPLC system (Jasco). The analysis conditions were the pump PU9
80, column internal temperature 60 ° C, AS-950-1
Inject 10 μl with 0 auto sampler and absorb 348
nm, spectroscopy at 455 nm, calibrated with Jasco FP 920 detector.

Approximately 5 g of a sample is shredded and ground, and then subjected to a method such as Lee (Lee, Eung-Ho, et al., Bull, Korean Fish Soc. 17).
(5), 368-372 (1984)), and nucleic acid-related substances were extracted and quantified by Gilson-805 HPLC. Analysis conditions are μ-Bond
Using an apak C ₁₈ (3.9 mm id × 30.0 cm) column, a 1% triethylamine-phosphoric acid (pH 6.5) solution was used as a mobile phase, at a flow rate of 2.0 ml / min and a UV detector (2
54 nm) at a temperature of 40 ° C.

The results of the quantification of the free amino acids and nucleic acid-related substances thus determined are shown in Tables VIII and IX. Table V
As shown in III, in the treated group bred with the crude drug composition-added feed of the present invention, the total amount of free amino acids appeared higher than that of the control group, particularly lysine and alanine.
e), it was found that arginine was contained in a large amount. According to Table IX, the nucleic acid-related substance had a high ATP in the treated group and a high IMP in the control group, which was accumulated in the form of IMP immediately after the animal died until dephosphorylation of ATP occurred and before decay. In view of this, it is assumed that the change in the nucleic acid-related substance occurs earlier in the control group than in the treated group.

[0048]

[Table 14]

[Table 15] FIG. 2 is a graph comparing the total amount of free amino acids and nucleic acid-related substances related to taste in fish meat of a treated group and a control group, which were bred by adding the crude drug composition of the present invention to feed.

According to FIG. 2, the total amount of free amino acids glutamic acid, proline, glycine, alanine, methionine and the like related to the taste of fish meat was also 14.
0 mg%, which was higher than the control group's 9.1 mg%. ATP, ADP, AMP, IMP related to the taste of fish meat
Was higher in the treated group (9.36 μmole / g) than in the control group (8.30 μmole / g), but not much different.

[0050]

As described above, the crude drug composition to be added to the cultured fish feed according to the present invention increases the survival rate and the growth rate of marine fish and freshwater fish, and increases the feed efficiency. Since it increases, it is possible to relatively reduce excretion and contribute to prevention of environmental pollution. Therefore, it is possible to reduce the cost of feed and maintenance during the cultivation of freshwater fish and marine fish, and furthermore, the fish cultivated with the addition of these are superior in taste and quality, so that they are higher than general cultivated fish. It can be sold at a price and has economic benefits. Furthermore, unlike the conventional aquaculture industry, where growth hormones and the like are administered to increase the growth rate, it uses Chinese herbal medicine, which is known to be almost non-toxic, and provides feeds that are harmless to fish and the human body. can do.

[Brief description of the drawings]

BRIEF DESCRIPTION OF DRAWINGS FIG. 1 is a graph showing the results of a sensory test on fish meat of a treated group and a control group bred by adding a crude drug composition of the present invention to feed.

FIG. 2 is a graph comparing the total amount of free amino acids and nucleic acid-related substances related to taste in fish meat of a treated group and a control group, which were bred by adding the crude drug composition of the present invention to feed.

Claims (11)

[Claims] 1. A feed additive composition comprising a crude drug component for promoting the growth of cultured fish. 2. Herbal medicine components include Yamako, licorice, citrus, bellflower, green skin, wood incense, kazushi, cuckoo, malt, daisy,
2. The composition according to claim 1, wherein the composition comprises acid soybean, sandy and Echijin. 3. Zirconium, sorghum, as crude drug components
3. The composition according to claim 2, further comprising gold and silver flowers, quince, forsythia, thorn garbage, juniper, herbal medicine, lotus meat, cinnamon bark, magnolia, or a mixture thereof. 4. The crude drug component includes zambia, sorghum,
The composition according to claim 2, further comprising gold and silver flowers, five skins, forsythia, thorns, and juniper. 5. Zirconium, sorghum, as crude drug components
3. The composition according to claim 2, further comprising gold and silver flowers, five skins, forsythia, thorns, juniper, herbal medicine, and lotus meat. 6. The composition according to claim 2, further comprising a skin herb, a magnolia, a herbal medicine and a lotus meat as a crude drug component. 7. 24 parts by weight of Yamako, 20 parts by weight of licorice, 1 each of citrus, bellflower, green skin, wood incense, incense and cuckoo.
8 parts by weight, 12 parts by weight each of malt, cinnamon and soybean jujube, 8 parts by weight of sand seed, sandalwood, soybean, Echijin, gokakin, rye and forage, 10 parts by weight of gold and silver flower, and 6 5. A weight part comprising:
A composition according to claim 1. 8. 24 parts by weight of Yamako, 20 parts by weight of licorice, 18 parts by weight of citrus, bellflower, green skin, wood incense, incense, cuckoo, mountain herb and lotus root meat, 12 parts by weight of malt, cinnamon and acid soybean. Parts by weight, 8 parts by weight each of sand, sandalwood, sow oak, masutoshi and gold and silver flowers, 6 parts by weight of quince, forsythia and forage, and 5 parts by weight of juniper A composition according to claim 5. [9] Yamako, Kiko shell, bellflower, green skin, wood incense, incense, cuckoo, malt, cinnamon, acid jujube, sand hull, cinnamon,
7. The composition according to claim 6, comprising 3 parts by weight of each of Koboku and Echijin and 4 parts by weight of each of herbal medicine, lotus meat and licorice. 10. A method for promoting the growth of cultured fish, which comprises adding a feed additive composition containing a crude drug component to the feed and administering the composition to the cultured fish. 11. The composition is added to feed for cultured fish at a concentration of 0.1%.
The method according to claim 10, characterized in that it is added at a ratio of from 1.0 to 1.0% by weight.