JPH10314273A - Medical vessel - Google Patents
Medical vesselInfo
- Publication number
- JPH10314273A JPH10314273A JP9144598A JP14459897A JPH10314273A JP H10314273 A JPH10314273 A JP H10314273A JP 9144598 A JP9144598 A JP 9144598A JP 14459897 A JP14459897 A JP 14459897A JP H10314273 A JPH10314273 A JP H10314273A
- Authority
- JP
- Japan
- Prior art keywords
- container
- main body
- communication
- medical
- communication port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Purses, Travelling Bags, Baskets, Or Suitcases (AREA)
- Package Specialized In Special Use (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、医療用容器に関するも
のであり、より詳細には、他の薬剤、例えば、抗生物質
等の薬剤を無菌的に混注した後の薬液を投与する場合に
用いられる連結部付き医療用容器に関するものである。
特に、連結部の取付が簡単であること、連結部の無菌維
持及び安全性が高いこと、及び使用の際の混注、混合操
作が容易である医療用容器に関するものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical container, and more particularly to a medical container used for administering a drug solution after aseptically co-injecting another drug such as an antibiotic. The present invention relates to a medical container with a connecting portion to be used.
In particular, the present invention relates to a medical container in which the attachment of the connecting portion is simple, the aseptic maintenance and safety of the connecting portion are high, and the co-injection and mixing operation at the time of use are easy.
【０００２】[0002]
【従来の技術】点滴注射に用いられる輸液、透析液、臓
器保存液等のバック、コンテナ等の医療用容器は、一般
に樹脂容器である。また輸液にはその使用時に抗生物質
などが混注、混合された後に点滴注射されるものがあ
る。このような混注、或いは混合には注射器が使用され
る。例えば、抗生物質の入ったバイアルに溶解液が注射
器を介して入れられる。抗生物質と溶解液とが混合さ
れ、混合液は注射器でバイアル内から吸い戻される。そ
して、輸液容器の排出口に注射器が刺通され、その混合
液が輸液容器内に充填される。また、最近、かかる煩雑
操作を省略するため、医療用容器にバイアル等の連結部
を備えたものが種々提案されている。連結部を備えた医
療用容器には薬液或いは溶解液を収容した樹脂容器にバ
イアル等の連通手段のみを具備したものと、樹脂容器と
バイアル等の薬剤容器とを連結部で既に連結して、使用
時まで各容器内同士が連通されない状態におかれるもの
とがある。前者はいわゆるハーフキット医療用容器と一
般に称され、後者はフルキット医療用容器と称されてい
る。2. Description of the Related Art Medical containers such as bags and containers for infusions, dialysis solutions, organ preservation solutions and the like used for infusion are generally resin containers. In addition, some infusions are infused with antibiotics or the like at the time of use, and are then injected by infusion after mixing. A syringe is used for such co-injection or mixing. For example, a lysate is placed via a syringe into a vial containing the antibiotic. The antibiotic and the lysis solution are mixed, and the mixture is drawn back out of the vial with a syringe. Then, the syringe is pierced through the outlet of the infusion container, and the mixed solution is filled in the infusion container. Recently, various types of medical containers provided with a connecting portion such as a vial have been proposed in order to eliminate such complicated operations. The medical container provided with a connecting portion is provided with only a communicating means such as a vial to a resin container containing a drug solution or a solution, and the resin container and a drug container such as a vial are already connected at the connecting portion, Some containers remain in a state where they are not communicated with each other until use. The former is commonly referred to as a so-called half-kit medical container, and the latter is referred to as a full-kit medical container.
【０００３】ハーフキット医療用容器としては、例え
ば、可撓性容器と、該容器の上端から上方に伸びる筒状
の収容カプセルとから構成され、カプセル内に連通手段
である両頭刺通型の連通針が収容され、使用時に連通針
の一端を薬剤容器の口部ゴム栓に刺通し、連通針の他端
を可撓性容器の上端に設けたゴム栓に刺通して薬剤容器
内と可撓性容器内とを連通させる薬剤容器の連通手段を
備えた溶解液容器が提案されている（特開平７−３２８
０９７号公報）。筒状カプセルの下部開口は可撓性容器
の上端に密封連結され、上部開口はシール部材によって
密封され、連通針はカプセル内に無菌的に収容されてい
る。フルキット医療用容器としては、例えば、溶解液容
器と、連結部として溶液容器の上端に設けた筒状のガイ
ドカプセルと、ガイドカプセル内を上下動可能に設けた
両頭刺通型の連通針と、バイアル等の薬剤容器と、内部
にその薬剤容器を保持するホルダーと、ホルダーを収容
しガイドカプセルの開口部を回動可能に密封するキャッ
プとからなる輸液用容器が提案されている（特開平７−
２７５３２４号公報）。かかる輸液用容器はキャップを
回転させることにより、ホルダーが回転することなく連
通針に向かって移動し、薬剤容器の口部ゴム栓は連通針
の一端に刺通され、また溶解液容器の連結部のゴム栓は
連通針の他端に刺通され、この結果薬剤容器内と溶解液
容器内とが連通されるものである。[0003] A half-kit medical container is composed of, for example, a flexible container and a cylindrical housing capsule extending upward from the upper end of the container. A needle is accommodated, and in use, one end of the communication needle is pierced into the rubber stopper at the mouth of the medicine container, and the other end of the communication needle is pierced through a rubber stopper provided at the upper end of the flexible container. A dissolving solution container provided with a communication means for a medicine container for communicating the inside with the inside has been proposed (JP-A-7-328).
No. 097). The lower opening of the cylindrical capsule is hermetically connected to the upper end of the flexible container, the upper opening is sealed by a sealing member, and the communication needle is aseptically accommodated in the capsule. As a full kit medical container, for example, a dissolving solution container, a cylindrical guide capsule provided at the upper end of the solution container as a connecting portion, and a double-head piercing type communication needle provided vertically movably in the guide capsule An infusion container has been proposed which comprises a medicine container such as a vial, a holder for holding the medicine container therein, and a cap for accommodating the holder and rotatably sealing the opening of the guide capsule (Japanese Patent Application Laid-Open No. HEI 9-208572). 7-
275324). By rotating the cap, the infusion container moves toward the communication needle without rotating the holder, the rubber stopper at the mouth of the medicine container is pierced into one end of the communication needle, and the connecting portion of the solution container is connected. The rubber stopper is pierced into the other end of the communication needle, and as a result, the inside of the medicine container and the inside of the solution container are connected.
【０００４】[0004]
【発明が解決しようとする課題】しかしながら、従来の
連結部を具備した医療用容器には未だ以下の問題点があ
る。医療用容器における連結部に設けられる連通手段は
両頭刺通型の連通針であるため、カプセル内に無菌状態
で、しかも使用時に移動可能に配する必要がある。特
に、その移動に際しては薬剤容器の口部が可撓性容器の
ゴム栓より先に連通針で刺通されなければならないとい
う構成要件が課せられるため、カプセル内の収容構造が
複雑となるおそれがある。また連通手段が両頭刺通型の
連通針であるため、可撓性容器の連結部或いは連結口に
ゴム栓を設ける必要があり、また使用に際して可撓性容
器のゴム栓にも連通針を刺通する等の操作が必要である
ため、その連通操作が必ずしもスムーズに行えるとは限
らない。従って、本発明は、連結部の取付が簡単で、連
結部の無菌維持及び安全性が高く、更には使用の際の混
注、混合操作が容易にできる医療用容器を提供すること
を目的としている。However, the medical container provided with the conventional connecting portion still has the following problems. Since the communication means provided at the connection portion of the medical container is a double-headed communication needle, it is necessary to arrange the medical device aseptically in the capsule and to be movable during use. In particular, when moving the medicine container, there is a requirement that the mouth of the medicine container must be pierced with a communication needle before the rubber stopper of the flexible container, so that the accommodation structure in the capsule may be complicated. is there. Further, since the communication means is a double-headed communication needle, it is necessary to provide a rubber stopper at the connection portion or the connection port of the flexible container. In use, the communication needle is also inserted into the rubber stopper of the flexible container. Since an operation such as communication is required, the communication operation is not always performed smoothly. Accordingly, an object of the present invention is to provide a medical container in which the connecting portion can be easily attached, aseptic maintenance and safety of the connecting portion are high, and co-injection and mixing operation at the time of use can be easily performed. .
【０００５】[0005]
【課題を解決するための手段】本発明は、薬液が収容さ
れた樹脂容器の本体に他の薬剤容器が連結される連結部
を有する医療用容器において、上記連結部における連通
口は上記本体内に存在し、その周縁が該本体内壁面と液
密に密着シールされて閉止され、且つ該密着シール部が
剥離可能なシールであることを特徴とする医療用容器を
提供することにより、上記目的を達成したものである。According to the present invention, there is provided a medical container having a connecting portion for connecting another drug container to a main body of a resin container containing a chemical solution, wherein a communication port in the connecting portion is provided in the main body. Wherein the peripheral edge of the medical container is tightly sealed with the inner wall surface of the main body in a liquid-tight manner and is closed, and the tightly-sealed portion is a peelable seal. Is achieved.
【０００６】上記樹脂容器に収容される薬液は、一般に
電解質液である。例えば、乳酸、酢酸、重炭酸等を含む
リンゲル液、糖、アミノ酸、ペプチド、脂肪等を含む高
カロリー輸液、透析液、臓器保存液等の溶液である。
尚、薬液は凍結乾燥薬剤の単なる溶解液、希釈液でも良
く、かかる薬液は単純な無菌水であっても良い。薬液
は、樹脂容器内に液密に収容された後に蒸気滅菌処理さ
れるものである。蒸気滅菌処理は温度１００℃〜１４０
℃、特に温度１０５℃〜１１５℃の範囲で滅菌処理する
ことが望ましい。上記範囲を下回る滅菌温度では、時間
がかかり、また滅菌が不十分となるおそれがある。一
方、上記範囲上回る滅菌温度ではプラスチック容器や包
装材が熱変形、熱変質等を起こして好ましくない。The chemical solution contained in the resin container is generally an electrolyte solution. Examples thereof include Ringer's solution containing lactic acid, acetic acid, bicarbonate and the like, high calorie infusion containing sugar, amino acid, peptide, fat, etc., dialysate, organ preservation solution and the like.
The chemical may be a simple solution or dilution of the lyophilized drug, and the chemical may be simple sterile water. The chemical is steam sterilized after being housed in a resin container in a liquid-tight manner. Steam sterilization treatment at a temperature of 100 ° C to 140 ° C
It is desirable to sterilize at a temperature of 105 ° C., particularly 105 ° C. to 115 ° C. At a sterilization temperature below the above range, it takes time and sterilization may be insufficient. On the other hand, at a sterilization temperature higher than the above range, the plastic container and the packaging material are undesirably subjected to thermal deformation, thermal deterioration, and the like.
【０００７】上記樹脂容器は可撓性壁を有する。可撓性
壁は撓むことにより容器内の容積が容易に変化するもの
であれば良い。また、樹脂容器壁は内容物の確認できる
程度に透明性を有することが望ましい。容器内での薬剤
の状態を確認する上で必要となるからである。上記樹脂
容器はインフレーションフィルム、チューブ、シート及
びフィルムから成形したもの、押出成形、射出成形、又
はブロー成形したものである。医療用容器の樹脂素材と
してはポリオレフィン系樹脂、塩化ビニル、塩化ビニリ
デン系樹脂、ポリエステル系樹脂、ポリビニルアルコー
ル系樹脂、ポリアクリルニトリル系樹脂、ポリアクリル
酸系樹脂、ポリアミド系樹脂等の汎用樹脂である。また
樹脂容器は単層又は多層で形成されていても良い。樹脂
容器内の薬剤と接触する最内層は、薬剤に影響を与えな
い、また溶出物が生じない樹脂層であるあることが望ま
しい。このような樹脂としては、ポリオレフィン系樹脂
が望ましく、例えば、低、中、高−密度ポリエチレン、
ポリプロピレン等の低級オレフィン樹脂等が挙げられ
る。また、樹脂容器壁にはガスバリアー性層が形成され
ていることが望ましい。特に、酸素等を容易に透過しな
い層であることが望ましい。このようなガスバリアー性
層としては、殆ど、又は全くガスを透過させないアルミ
ニウム等の金属層や酸化珪素、酸化マグネシウム、酸化
チタン等の無機蒸着層であり、またポリ塩化ビニリデ
ン、ポリエステル、ナイロン、エチレン−ビニルアルコ
ール共重合体、フッ素系樹脂等のようにガスバリアー性
の高い樹脂層である。樹脂容器におけるガスバリアー性
層の酸素透過量は４０ｃｃ・２０μ／ｍ2・ｄａｙ・ａ
ｔｍ（温度：２０℃）以下、特に、３０ｃｃ・２０μ／
ｍ2・ｄａｙ・ａｔｍ以下、また好ましくは５ｃｃ・２
０μ／ｍ2・ｄａｙ・ａｔｍ以下、更には１ｃｃ・２０
μ／ｍ2・ｄａｙ・ａｔｍ以下であることが望ましい。
また樹脂容器の壁は上述のように内部の薬剤が確認でき
る程度に透明性を有することが望まれる。このため、ガ
スを全く透過させない優れた機能を有する上記アルミニ
ウム層等の金属層から成る壁は少なくとも一部において
その金属層が剥離可能に形成されていることが望まし
い。かかる層を有した樹脂容器においては高圧蒸気滅菌
の加熱時に薬剤の変質を十分に防止することができる。[0007] The resin container has a flexible wall. The flexible wall may be any as long as the volume in the container is easily changed by bending. Further, it is desirable that the resin container wall has transparency to the extent that the contents can be confirmed. This is because it is necessary to confirm the state of the medicine in the container. The resin container is formed from an inflation film, a tube, a sheet, and a film, or is formed by extrusion, injection, or blow molding. The resin material of the medical container is a general-purpose resin such as polyolefin resin, vinyl chloride, vinylidene chloride resin, polyester resin, polyvinyl alcohol resin, polyacrylonitrile resin, polyacrylic acid resin, polyamide resin, and the like. . Further, the resin container may be formed in a single layer or a multilayer. The innermost layer in contact with the drug in the resin container is desirably a resin layer that does not affect the drug and does not generate elutes. As such a resin, a polyolefin-based resin is desirable, for example, low, medium, high-density polyethylene,
Examples include lower olefin resins such as polypropylene. It is desirable that a gas barrier layer is formed on the resin container wall. In particular, a layer that does not easily transmit oxygen or the like is desirable. Examples of such a gas barrier layer include a metal layer made of aluminum or the like which hardly transmits gas at all or an inorganic vapor-deposited layer made of silicon oxide, magnesium oxide, titanium oxide, etc., and polyvinylidene chloride, polyester, nylon, ethylene, and the like. -A resin layer having a high gas barrier property, such as a vinyl alcohol copolymer and a fluororesin. The oxygen permeation amount of the gas barrier layer in the resin container is 40 cc · 20 μ / m 2 · day · a
tm (temperature: 20 ° C.) or less, especially 30 cc · 20 μ /
m 2 · day · atm or less, preferably 5 cc · 2
0 μ / m 2 · day · atm or less, further 1 cc · 20
It is desirably not more than μ / m 2 · day · atm.
Further, it is desired that the wall of the resin container has such transparency that the medicine inside can be confirmed as described above. For this reason, it is desirable that at least a part of the wall made of a metal layer such as the aluminum layer having an excellent function of not allowing gas to permeate at all be formed so that the metal layer can be peeled off. In the resin container having such a layer, deterioration of the medicine can be sufficiently prevented at the time of heating in high-pressure steam sterilization.
【０００８】樹脂容器の本体は薬剤容器内と連通するた
めの連結部を有している。かかる連結部の樹脂容器側の
連通口は従来のようにゴム栓などを有していない。連結
部の樹脂容器側の連通口は樹脂容器の本体内に存在して
いる。従って、連結部は連通用パイプなどの一端が本体
内に差し込まれた構造となっており、連通用パイプは直
接本体に取付け或いは一体成形されていても良く、ま
た、本体に設けた連結ポートなどを介して本体に液密に
取付られていても良い。上記連通口はその周縁が本体の
内壁面と液密に密着シールされて閉止されている。連通
口の周縁部と本体の内壁面との密着シール部には接着剤
を介した液密な確実シール或いは樹脂同士の熱溶着シー
ル等を挙げることができる。接着剤としては、ケトン系
溶媒、エステル系溶媒、エーテル系溶媒、炭化水素系溶
媒、ハロゲン化炭化水素系溶媒などの溶媒接着剤、或い
は変性オレフィン類、ホットメルト類等の樹脂接着剤を
介した密封シール等がある。また熱溶着シールとして
は、ヒートシール、インパルスシール等の外部加熱によ
る接着、又は超音波接合、高周波接合等の内部加熱によ
る接着等を挙げることができる。特に、密着シールは熱
溶着シールが好ましい。熱溶着シールであれば、本体の
外壁側からのシールが可能となり、シールの際に本体内
を汚染するおそれがない。[0008] The main body of the resin container has a connecting portion for communicating with the inside of the medicine container. The communication port on the resin container side of the connecting portion does not have a rubber stopper or the like as in the related art. The communication port on the resin container side of the connection portion exists in the main body of the resin container. Accordingly, the connecting portion has a structure in which one end of a communication pipe or the like is inserted into the main body, and the communication pipe may be directly attached to the main body or may be integrally formed, or a connection port provided in the main body. It may be attached to the main body in a liquid-tight manner via the. The communication port is closed by sealing its peripheral edge to the inner wall surface of the main body in a liquid-tight manner. The tight seal between the peripheral edge of the communication port and the inner wall surface of the main body may be a liquid-tight reliable seal via an adhesive or a heat-sealing seal between resins. As the adhesive, a solvent adhesive such as a ketone solvent, an ester solvent, an ether solvent, a hydrocarbon solvent, a halogenated hydrocarbon solvent, or a resin adhesive such as a modified olefin or a hot melt is used. There are hermetic seals and the like. Examples of the heat-sealing seal include bonding by external heating such as heat sealing and impulse sealing, and bonding by internal heating such as ultrasonic bonding and high-frequency bonding. In particular, a heat seal is preferably used as the close seal. With a heat-sealed seal, sealing can be performed from the outer wall side of the main body, and there is no risk of contaminating the inside of the main body during sealing.
【０００９】上記密着シールは剥離可能なシールであ
る。剥離可能なシールは、通常ピールシール或いは弱シ
ールとも称され、外部から容器の室或いは容器を圧迫
し、内部が一定の昇圧状態にさせたときに剥離すること
ができるようなシール、或いは容器外壁のそれぞれを把
持して引っ張ったときに剥離することのできるシール等
である。このような密着シールの剥離強度は、容器等の
室内の圧が０．０１〜１．０Ｋｇｆ／ｃｍ2、特に、
０．０５〜０．５Ｋｇｆ／ｃｍ2の昇圧で剥離する強度
が望ましい。上記範囲を下回る強度であれば、製造、運
搬、保存時等の隔離状態を保つための安全性に欠ける。
上記範囲を上回る強度であれば、用時に室と室同士の連
通操作を容易にすることができなくなるおそれがある。
上記ピールシールを形成する場合に、両者の接着樹脂層
が異なる樹脂のブレンド物であることが望ましい。特
に、異なる樹脂は、熱溶融開始温度、或いはピカッド軟
化点が異なり、相溶性のあまりない樹脂ブレンド物から
なることが望ましい。かかるブレンド物層を有すること
より、ピールシール接着のシール温度条件設定が簡単に
できる。また、ピールシール接着に求められるシール強
度、即ち、使用時の外力による易剥離性と、保存時に剥
離が生じないシール強度との関係を厳密に設定すること
ができる。即ち、内層に相溶性の異なる樹脂を溶融混合
し、これをシート状に成形することによって、ミクロ的
に熱接着性の異なる部分に分離した表面としたものであ
る。そして、任意の温度におけるその接着表面相互のミ
クロ的な部分の熱溶融性を決めることにより、シール強
度の強弱を正確に付け、上記効果を容易に達成するもの
である。The above-mentioned close seal is a peelable seal. The peelable seal is usually called a peel seal or a weak seal, and is a seal that can be peeled off when the inside of the container or the container is squeezed from the outside and a constant pressure is raised, or the outer wall of the container. Is a seal or the like that can be peeled off when each of them is gripped and pulled. The peel strength of such a close-contact seal is such that the pressure inside a chamber such as a container is 0.01 to 1.0 kgf / cm 2 ,
It is desirable to have a peeling strength at a pressure of 0.05 to 0.5 kgf / cm 2 . If the strength is lower than the above range, the safety for maintaining an isolated state at the time of production, transportation, storage and the like is lacking.
If the strength exceeds the above range, there is a possibility that the communication operation between the rooms cannot be easily performed at the time of use.
When the peel seal is formed, it is desirable that both adhesive resin layers are blends of different resins. In particular, it is desirable that the different resins be made of resin blends having different hot-melting onset temperatures or Picad softening points and little compatibility. By having such a blended material layer, it is possible to easily set the sealing temperature conditions for peel seal bonding. Further, the relationship between the seal strength required for peel seal adhesion, that is, the easy peelability due to external force during use, and the seal strength that does not cause peeling during storage can be strictly set. That is, a resin having different compatibility is melt-mixed in the inner layer, and this is formed into a sheet to form a surface which is microscopically separated into portions having different thermal adhesiveness. Then, by determining the thermal fusibility of the microscopic portion between the bonding surfaces at an arbitrary temperature, the strength of the sealing strength is accurately provided, and the above-described effect is easily achieved.
【００１０】このような本発明に係る連結部を具備した
医療用容器にあっては、連結部における樹脂容器側の連
通口に刺通用ゴム栓等を設けたりする必要がない。連通
手段は樹脂容器側の連通口と既に通じる状態に置くこと
ができるため、少なくとも薬剤容器の口部にのみ刺通す
る通常の連通針をでよい。また、その連通針は無菌維持
用のカプセル内で移動可能に設ける必要もなく、薬剤容
器の口部と樹脂容器側の口部との刺通順序を考慮するこ
ともない。更に、薬剤容器等を既に取り付けたフルキッ
ト型の医療用容器とした場合には樹脂容器側の連通口を
薬剤容器内に直接連通させておくことができ煩雑な構造
を採ることもない。そして、使用に際しては、樹脂容器
の外側から内部を圧迫するのみで、密着シールが容易に
剥離し、樹脂容器側の連通口が開放されることとなり、
薬剤容器内と樹脂容器内とが極めて容易に連通する。In the medical container provided with such a connecting portion according to the present invention, it is not necessary to provide a rubber stopper or the like for piercing the communication port on the resin container side in the connecting portion. Since the communication means can be placed in communication with the communication port on the resin container side, a normal communication needle that penetrates at least only the mouth of the medicine container may be used. Further, the communication needle does not need to be provided movably in the capsule for maintaining sterility, and the piercing order between the mouth of the medicine container and the mouth of the resin container is not considered. Furthermore, in the case of a full-kit type medical container to which a medicine container or the like is already attached, the communication port on the resin container side can be directly connected to the inside of the medicine container, so that a complicated structure is not adopted. And, in use, only by pressing the inside from the outside of the resin container, the tight seal is easily peeled off, and the communication port on the resin container side is opened,
The inside of the medicine container and the inside of the resin container communicate extremely easily.
【００１１】本発明に係る請求項２記載の医療用容器
は、請求項１記載の医療用容器において、上記密着シー
ル部を非剥離状態に維持するための剥離防止材を上記連
通口が位置する本体の外壁面に設けることを特徴とす
る。剥離防止材は、本体内壁面と連通口の周縁とが離間
することを規制する部材である限りその構造を問わな
い。例えば、樹脂容器を外側から挟む一対の面と両面を
繋ぐ架橋面とからなるコ字形状に形成された部材で、そ
の一対の挟持面が上記連通口が位置する本体の外壁面を
押圧する作用があるものや、選択鋏等のようにクリップ
式で連通口を本体の外壁面から挟持するもの等を挙げる
ことができる。樹脂容器の密着シール部は高圧蒸気滅菌
処理中、製造時のライン工程上、或いは運搬中に不用意
な熱的或いは機械的な作用により剥離するおそれがあ
る。使用前からのこのような密着シールの剥離は著しく
医療用容器として安全性を損なう。このため、上記剥離
防止材を使用する前まで取り付けておけば、密着シール
部は剥離せず医療用容器として安全性が高まる。In the medical container according to a second aspect of the present invention, in the medical container according to the first aspect, the communication port is provided with a peel preventing material for maintaining the tightly sealed portion in a non-peeled state. It is provided on the outer wall surface of the main body. The structure of the anti-peeling material is not limited as long as it is a member that regulates separation between the inner wall surface of the main body and the peripheral edge of the communication port. For example, a member formed in a U-shape consisting of a pair of surfaces sandwiching the resin container from the outside and a bridging surface connecting both surfaces, and the pair of clamping surfaces presses the outer wall surface of the main body where the communication port is located. And a clip type such as selective scissors that clamps the communication port from the outer wall surface of the main body. The tightly sealed portion of the resin container may be peeled off due to careless thermal or mechanical action during high-pressure steam sterilization, during a production line process, or during transportation. Such peeling of the close seal before use significantly impairs the safety as a medical container. For this reason, if the anti-peeling material is attached before it is used, the tightly sealed portion does not peel off, and the safety as a medical container is enhanced.
【００１２】本発明に係る請求項３記載の医療用容器
は、請求項１又は２記載の医療用容器において、上記密
着シールは二条以上に分かれて設けられていることを特
徴とする。医療用容器は一般に安全性が厳しく要求され
る。このため、使用前から樹脂容器の連通口が開放され
たまま使用されることがあると、著しく安全性を損な
う。このため、連通口の密封性を容易に確認できるよう
にすることが望まれる。そこで、本発明に係る医療用容
器の如く、連通口の周縁における密着シールを２条以上
の複数のシート部として形成しておくと、最外輪シール
に当たる部分が剥離していたとすると、その外輪シール
部と内輪シール部との間に液が浸透し、外輪シール部等
の異常な光屈折状態が一目で分かる。このため、使用前
の密着シール部の密封性の確認が容易になされ、医療用
容器の安全性を保つことができる。A medical container according to a third aspect of the present invention is the medical container according to the first or second aspect, wherein the close contact seal is provided in two or more sections. Medical containers generally require strict safety. Therefore, if the resin container is used with the communication port opened before use, the safety is significantly impaired. For this reason, it is desired that the sealing property of the communication port can be easily confirmed. Therefore, as in the case of the medical container according to the present invention, if the close contact seal at the peripheral edge of the communication port is formed as a plurality of sheet sections of two or more, if the portion corresponding to the outermost ring seal is peeled off, the outer ring seal The liquid permeates between the portion and the inner ring seal portion, and an abnormal light refraction state of the outer ring seal portion and the like can be seen at a glance. Therefore, it is easy to confirm the sealing property of the close-contact seal portion before use, and the safety of the medical container can be maintained.
【００１３】本発明に係る請求項４記載の医療用容器
は、請求項１〜３の何れかに記載の医療用容器におい
て、上記連結部に上記薬剤容器に連通するため連通針が
設けられ、上記連通針と上記本体内の連通口と通じてい
ることを特徴とする。このように、連通針と連通口とが
直接通じていることにより、ハーフキット型の医療用容
器において、連通針は両頭刺通型とすることなく、また
薬剤容器の口部に刺通させるのみで容易に連通する。ま
た、無菌維持カプセル内で連通針を必ずしもスライドさ
せて設ける必要もない。本発明に係る請求項５記載の医
療用容器は、請求項１〜３記載の医療用容器において、
上記連結部に除菌フィルタが設けられ、該フィルタと上
記本体内に存在する連通口とが通じていることを特徴と
する。上記連結部において上記除菌フィルタは、その保
存時において薬液等によって濡れてその機能及び性能を
損なうことはない。除菌フィルタは孔径が０．８μｍ以
下、好ましくは０．４５μｍ以下、特に０．２μｍ以下
であることが望ましい。このような範囲内であれば除菌
ができる。本発明に係る請求項６記載の医療用容器は、
請求項１〜３記載の医療用容器において、上記連結部に
は上記他の薬剤容器が既に設けられ、上記薬剤容器内は
上記本体内の連通口と通じていることを特徴とする。上
記樹脂容器と薬剤容器とを既に連結したフルキット型の
医療用容器を提供した場合には、薬剤容器内と連通口と
を通じた状態としても、連通口は使用時まで密封されて
いるので、保存上問題はなく連結部に連通針等の複雑な
連通手段を設ける必要もない。このため、医療用容器は
製造が簡単にでき、操作も簡単にできる。A medical container according to a fourth aspect of the present invention is the medical container according to any one of the first to third aspects, wherein a communication needle is provided at the connecting portion for communicating with the medicine container, The communication needle communicates with the communication port in the main body. As described above, since the communication needle and the communication port are in direct communication with each other, in the half-kit type medical container, the communication needle does not need to be a double-headed piercing type, and only pierces the mouth of the medicine container. To communicate easily. Further, it is not always necessary to slide the communication needle in the sterile maintenance capsule. The medical container according to claim 5 according to the present invention is the medical container according to claims 1 to 3,
A germicidal filter is provided in the connecting portion, and the filter and a communication port existing in the main body communicate with each other. At the connection portion, the sterilization filter does not get wet with a chemical solution or the like during storage and does not impair its function and performance. It is desirable that the filter has a pore size of 0.8 μm or less, preferably 0.45 μm or less, and particularly preferably 0.2 μm or less. Bacteria can be removed within such a range. The medical container according to claim 6 according to the present invention,
The medical container according to any one of claims 1 to 3, wherein the other drug container is already provided in the connecting portion, and the inside of the drug container communicates with a communication port in the main body. When providing a full-kit type medical container in which the resin container and the drug container are already connected, even in a state where the inside of the drug container and the communication port are provided, since the communication port is sealed until use, There is no problem in storage, and there is no need to provide a complicated communication means such as a communication needle at the connection portion. For this reason, the medical container can be easily manufactured and operated.
【００１４】[0014]
【実施例】以下、本発明に係る医療用容器の好ましい実
施例を添付図面を参照しながら詳述する。図１は本発明
に係る医療用容器の第一実施例の正面図である。図２は
第一実施例の医療用容器の正断面図である。図３は第一
実施例の医療用容器の側断面図である。図４（Ａ）及び
（Ｄ）は医療用容器に用いる連通パイプの正面図、底面
図、側面図、及び上面図である。図５（Ａ）及び（Ｄ）
は医療用容器に用いる剥離防止材の正面図、底面図、側
面図、及び上面図である。図６は使用時の第一実施例の
医療用容器の正断面図である。DESCRIPTION OF THE PREFERRED EMBODIMENTS Preferred embodiments of the medical container according to the present invention will be described below in detail with reference to the accompanying drawings. FIG. 1 is a front view of a first embodiment of the medical container according to the present invention. FIG. 2 is a front sectional view of the medical container of the first embodiment. FIG. 3 is a side sectional view of the medical container of the first embodiment. 4A and 4D are a front view, a bottom view, a side view, and a top view of a communication pipe used for a medical container. FIG. 5 (A) and (D)
FIG. 4 is a front view, a bottom view, a side view, and a top view of a peeling prevention material used for a medical container. FIG. 6 is a front sectional view of the medical container of the first embodiment in use.
【００１５】 図１乃至図６に示す如く、本実施例の医
療用容器１は、薬液３が収容された樹脂容器の本体２に
他の薬剤容器２１が連結される連結部４を有する。医療
用容器１は上記連結部４における連通口５Ａは上記本体
２内に存在し、その周縁が本体２内壁面と液密に密着シ
ールされて閉止され、且つ密着シール部６、７が剥離可
能なシールである。上記密着シール部６、７とを非剥離
状態に維持するための剥離防止材８を上記連通口５Ａが
位置する本体２の外壁面に設ける。上記密着シール６、
７は二条に分かれて設けられている。上記連結部４に薬
剤容器２１内と連通するための連通針９が設けられ、連
通針９と上記本体２内に存在する連通口５Ａとが通じて
いる。As shown in FIGS. 1 to 6, the medical container 1 of the present embodiment has a connecting portion 4 for connecting another drug container 21 to a main body 2 of a resin container in which a drug solution 3 is stored. In the medical container 1, the communication port 5A in the connecting portion 4 is present in the main body 2, the peripheral edge thereof is tightly sealed to the inner wall surface of the main body 2 in a liquid-tight manner, and the tight seal portions 6, 7 are peelable. It is a good seal. An anti-peeling material 8 for maintaining the above-mentioned close contact seal portions 6 and 7 in a non-peeling state is provided on the outer wall surface of the main body 2 where the communication port 5A is located. The close contact seal 6,
7 is provided in two sections. The connection portion 4 is provided with a communication needle 9 for communicating with the inside of the medicine container 21, and the communication needle 9 communicates with the communication port 5 </ b> A present in the main body 2.
【００１６】本実施例の医療用容器１を更に詳しく説明
すると、医療用容器１に用いられる樹脂容器の本体２は
ブロー成形物からなり、壁厚が２５０μｍで容量が１５
０ｍｌである。本体２はブロー成形時に排出ポート１１
及び連結ポート１２が一体形成されている。容器本体２
は直鎖状低密度ポリエチレン及びポリプロピレンの混合
組成物を内層とし、外層を上記直鎖状低密度ポリエチレ
ンとして二色形成されている（図示を省略）。混合組成
物は、直鎖状低密度ポリエチレン（密度：０．９３５ｇ
／ｃｍ3、ＭＩ：１、融点：１２６℃）とポリプロピレ
ン（密度：０．９００ｇ／ｃｍ3、ＭＩ：０．７、融
点：１６０℃）とを７０：３０の割合で混合したもので
ある。図２〜図５に示す如く容器本体２の連結ポート１
２内には連通用パイプ５が取り付けられ、連通用パイプ
５は直鎖状低密度ポリエチレン及びポリプロピレンから
なる定型性の射出成形物からなる。連通用パイプ５の一
端は閉塞され、他端には開口フランジ５Ｂが形成されて
いる。連通用パイプ５の閉塞端はほぼ矩形状に形成され
て本体２内に挿入されて配され、フランジ５Ｂを介して
連通ポート１２に液密に嵌着される。また連通用パイプ
の閉塞端の平坦壁面には連通口５Ａ、５Ａが形成されて
いる。The medical container 1 of this embodiment will be described in more detail. The main body 2 of the resin container used for the medical container 1 is made of a blow-molded product, has a wall thickness of 250 μm, and has a capacity of 15 μm.
0 ml. The main body 2 has a discharge port 11 during blow molding.
And the connection port 12 are integrally formed. Container body 2
Has a mixed composition of linear low-density polyethylene and polypropylene as the inner layer, and the outer layer is formed in two colors as the linear low-density polyethylene (not shown). The mixed composition is a linear low-density polyethylene (density: 0.935 g)
/ Cm 3 , MI: 1, melting point: 126 ° C.) and polypropylene (density: 0.900 g / cm 3 , MI: 0.7, melting point: 160 ° C.) at a ratio of 70:30. Connection port 1 of container body 2 as shown in FIGS.
A communication pipe 5 is mounted in the communication pipe 2, and the communication pipe 5 is made of a fixed injection molded product made of linear low-density polyethylene and polypropylene. One end of the communication pipe 5 is closed, and an opening flange 5B is formed at the other end. The closed end of the communication pipe 5 is formed in a substantially rectangular shape, is inserted into the main body 2, is disposed, and is fitted to the communication port 12 through the flange 5B in a liquid-tight manner. In addition, communication ports 5A, 5A are formed in the flat wall surface at the closed end of the communication pipe.
【００１７】連通用パイプ５のフランジ５Ｂの天面には
連通針９が固着され、連通針９の通路は連通用パイプ５
内と連通し連通口５Ａ、５Ａと通じている。更に、連通
針９の外側には筒状の収容カプセル１３が配せられ、収
容カプセル１３の下端は連結ポート１２に固着されてい
る。収容カプセル１３の上端開口は剥離可能な無菌維持
シール材１４で密封され、シール材１４は水蒸気透過性
で菌不通過の紙類及び樹脂部材で形成されている。図３
に示す如く連通口５Ａ、５Ａは本体２の内壁面で液密に
覆われ、連通口５Ａの周縁には二条の剥離可能な密着シ
ール部６、７が形成されている。密着シール部６は内輪
シールで密着シール部７は外輪シールとなっており、密
着シール部６と密着シール部７との間は目視で十分確認
できる程度に離間している。A communication needle 9 is fixed to the top surface of the flange 5B of the communication pipe 5, and the passage of the communication needle 9 is
The inside communicates with the communication ports 5A and 5A. Further, a cylindrical housing capsule 13 is disposed outside the communication needle 9, and the lower end of the housing capsule 13 is fixed to the connection port 12. The upper end opening of the storage capsule 13 is sealed with a peelable aseptic maintenance sealing material 14, and the sealing material 14 is formed of paper and a resin member which is water vapor permeable and does not pass through bacteria. FIG.
The communication ports 5A, 5A are liquid-tightly covered with the inner wall surface of the main body 2 as shown in FIG. 3, and two peelable close-contact seal portions 6, 7 are formed on the periphery of the communication port 5A. The contact seal portion 6 is an inner ring seal and the contact seal portion 7 is an outer ring seal, and the contact seal portion 6 and the contact seal portion 7 are separated from each other to the extent that they can be visually checked sufficiently.
【００１８】図３及び図５に示す如く連通口５Ａが位置
する本体２の外壁面には剥離防止材８が配せられ、剥離
防止材８は樹脂成形物からなる。剥離防止材８は一定間
隔おいて平行に離間する挟み部８Ａ、８Ａと、挟み部８
Ａ、８Ａ同士を繋ぐ架橋部８Ｂとからなり、全体として
側断面がコの字形状に形成されている。各挟み部８Ａに
は連通口５Ａの状態を確認観察する窓１５が形成され、
架橋部８Ｂには本体２の首部を外装する嵌合孔１６及び
装着スリット１７が形成されている。剥離防止材８を本
体２に装着する場合は装着スリット１７を無理開きし
て、本体２の首部に嵌合孔１６をはめ込む。かかる状態
で挟み部８Ａと架橋部８Ｂとの間には曲げ弾性変形が生
じ、挟み部８Ａ、８Ａはかかる弾性力により本体２の壁
を連通用パイプ５の連通口５Ａに向けて押圧する。容器
本体２内には連結される薬剤容器２１内の薬剤２２の溶
解液３が排出ポート１１から充填され、排出ポート１１
は止め材１９を介してゴム栓２０によって密封されてい
る。溶解液３は容器本体２及びカプセル１３内と共に１
１０℃で高圧蒸気滅菌処理され、医療用容器１とされ
る。As shown in FIGS. 3 and 5, on the outer wall surface of the main body 2 where the communication port 5A is located, a peel preventing material 8 is arranged, and the peel preventing material 8 is made of a resin molded product. The anti-peeling material 8 includes a pair of holding portions 8A and 8A which are spaced apart in parallel at a predetermined interval, and a holding portion 8A.
A, 8A, and a bridging portion 8B connecting the 8A to each other, and has a U-shaped side cross section as a whole. A window 15 for confirming and observing the state of the communication port 5A is formed in each of the holding portions 8A,
The bridging portion 8B is formed with a fitting hole 16 and a mounting slit 17 for covering the neck of the main body 2. When the anti-peeling material 8 is mounted on the main body 2, the mounting slit 17 is forcibly opened, and the fitting hole 16 is fitted into the neck of the main body 2. In this state, bending elastic deformation occurs between the holding portion 8A and the bridging portion 8B, and the holding portions 8A press the wall of the main body 2 toward the communication port 5A of the communication pipe 5 by the elastic force. The solution 3 of the medicine 22 in the medicine container 21 to be connected is filled into the container body 2 from the discharge port 11.
Is sealed by a rubber stopper 20 through a stopper 19. The solution 3 is contained in the container body 2 and the capsule 13 together with 1
The container is subjected to high-pressure steam sterilization at 10 ° C. to obtain a medical container 1.
【００１９】このように構成される医療用容器１では、
連結部４での部品点数は少なく、また連通針９の構造も
単純であり連結針９はカプセル１３内での移動もない。
また連結部４の滅菌処理も溶解液３と一緒にできるの
で、その後のカプセル１３内の無菌維持も十分に成され
る。また、容器本体２に剥離防止材８が設けられること
により、使用までの間に不用意な剥離が無いため、容器
本体２内の溶解液３は使用時まで安全に維持される、更
に、密着シール部６、７は二条となっているため、外輪
シール部７に異常があれば、内輪シール部６と外輪シー
ル部７との間に溶液が浸透し、その壁膜の色が変わって
いるので、使用前に安全か否かのチャックが容易にでき
る。医療用容器１を使用するには図６に示す如く、先ず
無菌維持シール材１４をカプセル１３から取り外し、薬
剤容器２１の口部２３をカプセル１３に差し込み、口部
２３に連通針９を刺通させる。次に、剥離防止材８を本
体２から取り外し、本体２を逆さにして握りしめ内部を
圧迫する。これにより、密着シール６、７が剥離し連通
口５Ａが開放する。かかる開放により、本体２内の溶解
液３の一部が薬剤容器２１内と流れ、容器２１内の薬剤
２２を溶解した後、再び容器本体２に薬剤２２を溶解し
た溶解液３を戻す。かかる操作後、排出ポート１１のゴ
ム栓２０に点滴針を刺通して点滴を開始する。従って、
薬剤２２を溶解液３に無菌的に簡単に溶解させることが
でき、その点滴操作も容易となる。In the medical container 1 configured as described above,
The number of parts in the connecting portion 4 is small, the structure of the communication needle 9 is simple, and the connecting needle 9 does not move in the capsule 13.
In addition, the sterilization of the connecting portion 4 can be performed together with the dissolving solution 3, so that the sterility of the capsule 13 can be sufficiently maintained thereafter. In addition, since the container body 2 is provided with the peel preventing material 8, there is no inadvertent peeling before use, so that the solution 3 in the container body 2 is safely maintained until use. Since the seal portions 6 and 7 have two lines, if there is an abnormality in the outer ring seal portion 7, the solution permeates between the inner ring seal portion 6 and the outer ring seal portion 7 and the color of the wall film changes. Therefore, it is easy to check whether or not it is safe before use. In order to use the medical container 1, as shown in FIG. 6, the sterile maintenance sealing material 14 is first removed from the capsule 13, the mouth 23 of the medicine container 21 is inserted into the capsule 13, and the communication needle 9 is pierced into the mouth 23. Let it. Next, the peeling prevention member 8 is removed from the main body 2 and the main body 2 is turned upside down and squeezed to press the inside. Thereby, the contact seals 6, 7 are peeled off, and the communication port 5A is opened. By this opening, a part of the solution 3 in the main body 2 flows into the medicine container 21 to dissolve the medicine 22 in the container 21 and then returns the solution 3 in which the medicine 22 is dissolved to the container body 2 again. After this operation, a drip needle is inserted into the rubber stopper 20 of the discharge port 11 to start drip infusion. Therefore,
The drug 22 can be easily and simply dissolved in the dissolving solution 3 in an aseptic manner, and the drip operation is also facilitated.
【００２０】次に、本発明に係る医療用容器の第二実施
例について添付図面の図７及び図８に従って詳述する。
図７は第二実施例の医療用容器の正断面図である。図８
は第二実施例の医療用容器の側断面図である。図９は第
二実施例の医療用容器に用いる除菌フィルタの正面図で
ある。第二実施例の医療用容器３１は、薬液３が収容さ
れた樹脂容器の本体３２に他の薬剤容器２１が連結され
る連結材３４を有し、連結材３４における連通口３５は
本体３２内に存在し、その周縁が本体３２内壁面と液密
に密着シールされて閉止され、且つ密着シール３６が剥
離可能なシールである点については第一実施例の医療用
容器１とほぼ同様である。また、上記本体３２内壁面と
周縁との密着シール３６を非剥離状態に維持するための
剥離防止材３８を連通口３５が位置する本体３２の外壁
面に設ける点も同様である。本実施例の医療用容器３１
が第一実施例の医療用容器１と異なる点は連結材３４に
は他の薬剤容器２１が既に設けられ、薬剤容器２１は本
体３２内の連通口３５と通じていることである。Next, a second embodiment of the medical container according to the present invention will be described in detail with reference to FIGS. 7 and 8 of the accompanying drawings.
FIG. 7 is a front sectional view of the medical container of the second embodiment. FIG.
FIG. 4 is a side sectional view of the medical container of the second embodiment. FIG. 9 is a front view of a sterilization filter used in the medical container of the second embodiment. The medical container 31 of the second embodiment has a connecting member 34 for connecting another drug container 21 to a main body 32 of a resin container in which the liquid medicine 3 is accommodated. , The peripheral edge of which is tightly sealed to the inner wall surface of the main body 32 in a liquid-tight manner and closed, and the adhesive seal 36 is a peelable seal, which is almost the same as the medical container 1 of the first embodiment. . The same applies to the point that a peeling prevention member 38 for maintaining the tight seal 36 between the inner wall surface of the main body 32 and the peripheral edge in a non-peeling state is provided on the outer wall surface of the main body 32 where the communication port 35 is located. Medical container 31 of the present embodiment
However, the difference from the medical container 1 of the first embodiment is that another medicine container 21 is already provided in the connecting member 34, and the medicine container 21 communicates with the communication port 35 in the main body 32.
【００２１】第二実施例の医療用容器３１を更に説明す
ると、容器本体３２は厚み２５０μｍのインフレーショ
ンフィルムを所定の長さに裁断し、裁断端部を熱溶着シ
ールして成形されている。本体３２の端部シール３２Ａ
には連結材３４が熱溶着の際に取り付けられ、端部シー
ル３２Ｂには排出部材４１が取り付けられている。連結
材３４は射出成形物からなり、閉止端部は本体３２内に
挿入され、開放端部は本体３２外に配されている。閉止
端部には連通口３５が形成され、開放端部にはフック顎
４２が形成されている。フック顎４２内には弾性を有す
るオーリングシール材４３が配され、シール材４３には
キャップを外した薬剤容器２１の口部２３が当接されて
いる。また、かかる接続は無菌雰囲気中で行われてい
る。図８に示す如く連結材３４の連通口３５は本体３２
内壁面で覆われて閉止されている。かかる連通口３５の
周縁と内壁面とは剥離可能なピールシールが成されてい
る。また、かかる連通口３５の本体の外壁面には洗濯挟
みと同様な構造の剥離防止材３８が設けられている。剥
離防止材３８の押圧部材４５内には乾燥剤４６が配さ
れ、乾燥剤４６は本体２越しに保存中の薬剤容器２１内
及び連結材３４内の乾燥を行っている。また連結材３４
は外層がポリオレフィン系の熱溶着シール層で、中間層
にはポリ塩化ビニリデン等の水分バリアー性層を有して
いる。連通材３４の通路には除菌フィルタ４７が配せら
れ、除菌フィルタ４７は孔径が０．４５μｍの親水性フ
ィルタからなる。図９に示す如く除菌フィルタ４７は中
心部が疎水処理され、除菌フィルタ４７の大部分が親水
性フィルタ部４７Ａからなり中心部にエア抜けの疎水フ
ィルタ部４７Ｂが形成されている。The medical container 31 of the second embodiment will be further described. The container main body 32 is formed by cutting a blown film having a thickness of 250 μm into a predetermined length and sealing the cut end by heat sealing. End seal 32A of main body 32
Is attached at the time of thermal welding, and a discharge member 41 is attached to the end seal 32B. The connecting member 34 is made of an injection-molded product, and has a closed end inserted into the main body 32 and an open end disposed outside the main body 32. A communication port 35 is formed at the closed end, and a hook jaw 42 is formed at the open end. An elastic O-ring seal member 43 is arranged in the hook jaw 42, and the mouth portion 23 of the drug container 21 with the cap removed is in contact with the seal member 43. Also, such connections are made in a sterile atmosphere. As shown in FIG. 8, the communication port 35 of the connecting member 34 is
It is covered and closed by the inner wall. A peel seal is formed between the peripheral edge of the communication port 35 and the inner wall surface. Further, on the outer wall surface of the main body of the communication port 35, a separation preventing member 38 having a structure similar to that of the laundry pinch is provided. A desiccant 46 is arranged in the pressing member 45 of the peeling prevention member 38, and the desiccant 46 dries the inside of the medicine container 21 and the connecting member 34 which are stored over the main body 2. In addition, connecting material 34
The outer layer is a heat-sealing seal layer of a polyolefin type, and the intermediate layer has a moisture barrier layer such as polyvinylidene chloride. A disinfecting filter 47 is provided in the passage of the communication member 34, and the disinfecting filter 47 is formed of a hydrophilic filter having a pore diameter of 0.45 μm. As shown in FIG. 9, the sterilizing filter 47 is subjected to a hydrophobic treatment at its central portion, and a large part of the sterilizing filter 47 is formed of a hydrophilic filter portion 47A, and a hydrophobic filter portion 47B through which air escapes is formed at the central portion.
【００２２】このように構成される医療用容器３１にあ
っては、第一実施例と同様に連結部での部品点数は少な
く、医療用容器３１の連結材３４に薬剤容器２１の口部
２３を無菌的に接続することができる。また、その使用
時の操作においても第一実施例の医療用容器と同様に簡
単に樹脂容器の本体３２内と薬剤容器２１内とを連通さ
せることができる。また、凍結乾燥物等の薬剤容器２１
等はその製造過程において多少の汚染不安が残る。しか
し、医療用容器３１の連結材３４には除菌フィルタ４７
が配せられるため、樹脂容器内に戻される混合液には細
菌等が混入するおそれが少ない。また保存時に連結材３
４内の除菌フィルタ４７が濡れてその機能を低下させる
おそれがない。医療用容器３１の剥離防止材３８の押圧
部材４５には乾燥剤４６が配されているため、本体３２
の壁越しに連通口３５から水分を積極的に取り出す作用
がある。このため、医療用容器３１の保存が長期間に及
んでも薬剤容器２１内の薬剤２２が水分等で変質するお
それがない。上記第一実施例において樹脂容器にブロー
成形物を用いたが第二実施例と同様にシート、フイルム
等から製造しても良い。また第一実施例においては、第
二実施例のように剥離防止材に乾燥剤を取り付けても良
し、除菌フィルタを設けても良い。また、第二実施例の
ように連結部に連通針を設けずバイアル等の口部を直接
連結できる構造を設けても良い。上記第二実施例におい
て第一実施例と同様に連通針を設けても良い。In the medical container 31 constructed as described above, the number of parts at the connecting portion is small as in the first embodiment, and the connecting portion 34 of the medical container 31 Can be connected aseptically. Also, in the operation at the time of use, the inside of the main body 32 of the resin container and the inside of the medicine container 21 can be easily communicated similarly to the medical container of the first embodiment. In addition, drug containers 21 such as freeze-dried products
Etc., there is some concern about contamination during the manufacturing process. However, the connecting material 34 of the medical container 31 has a sterilizing filter 47
Is disposed, so that the mixed liquid returned into the resin container is less likely to be mixed with bacteria and the like. In addition, at the time of preservation
There is no danger that the sterilization filter 47 in 4 will get wet and deteriorate its function. Since the desiccant 46 is disposed on the pressing member 45 of the peeling prevention member 38 of the medical container 31, the main body 32
Has the function of positively taking out moisture from the communication port 35 through the wall. Therefore, even if the medical container 31 is stored for a long period of time, there is no possibility that the medicine 22 in the medicine container 21 will be deteriorated by moisture or the like. In the first embodiment, a blow-molded product is used for the resin container. However, the resin container may be manufactured from a sheet, a film, or the like as in the second embodiment. In the first embodiment, a desiccant may be attached to the anti-peeling material as in the second embodiment, or a sterilization filter may be provided. Further, a structure that can directly connect the mouth portion such as a vial without providing a communication needle in the connecting portion as in the second embodiment may be provided. In the second embodiment, a communication needle may be provided as in the first embodiment.
【００２３】[0023]
【発明の効果】以上説明したように本発明に係る医療用
容器においては、上記連結部における連通口は上記本体
内に存在し、その周縁が該本体内壁面と液密に密着シー
ルされて閉止され、且つ該密着シール部が剥離可能なシ
ールであるので、連結部の取付が簡単で、連結部の無菌
維持及び安全性が高く、更には使用の際の混注、混合操
作が容易にできる。As described above, in the medical container according to the present invention, the communication port in the connecting portion is present in the main body, and its peripheral edge is tightly sealed to the inner wall surface of the main body in a liquid-tight manner and closed. In addition, since the close-contact seal portion is a peelable seal, the connection portion can be easily attached, aseptic maintenance and safety of the connection portion are high, and the co-injection and mixing operations at the time of use can be easily performed.
【図１】図１は本発明に係る医療用容器の第一実施例の
正面図である。FIG. 1 is a front view of a first embodiment of a medical container according to the present invention.
【図２】図２は第一実施例の医療用容器の正断面図であ
る。FIG. 2 is a front sectional view of the medical container of the first embodiment.
【図３】図３は第一実施例の医療用容器の側断面図であ
る。FIG. 3 is a side sectional view of the medical container of the first embodiment.
【図４】図４（Ａ）及び（Ｄ）は医療用容器に用いる連
通パイプの正面図、底面図、側面図、及び上面図であ
る。FIGS. 4A and 4D are a front view, a bottom view, a side view, and a top view of a communication pipe used for a medical container.
【図５】図５（Ａ）及び（Ｄ）は医療用容器に用いる剥
離防止材の正面図、底面図、側面図、及び上面図であ
る。FIGS. 5A and 5D are a front view, a bottom view, a side view, and a top view of a peeling prevention material used for a medical container.
【図６】図６は使用時の第一実施例の医療用容器の正断
面図である。FIG. 6 is a front sectional view of the medical container of the first embodiment in use.
【図７】図７は第二実施例の医療用容器の正断面図であ
る。FIG. 7 is a front sectional view of the medical container of the second embodiment.
【図８】図８は第二実施例の医療用容器の側断面図であ
る。FIG. 8 is a side sectional view of the medical container of the second embodiment.
【図９】図９は第二実施例の医療用容器に用いる除菌フ
ィルタの正面図である。FIG. 9 is a front view of a sterilization filter used for the medical container of the second embodiment.
１、３１ 医療用容器 ２、３２ 樹脂容器の本体 ３ 薬液 ４ 連結部 ５ 連通用パイプ ５Ａ 連通口 ６、７ 密着シール部 ８ 剥離防止材 ９ 連通針 DESCRIPTION OF SYMBOLS 1, 31 Medical container 2, 32 Main body of resin container 3 Chemical solution 4 Connecting part 5 Communication pipe 5A Communication port 6, 7 Close-sealing part 8 Peeling prevention material 9 Communication needle
Claims (6)
薬剤容器が連結される連結部を有する医療用容器におい
て、 上記連結部における連通口は上記本体内に存在し、その
周縁が該本体内壁面と液密に密着シールされて閉止さ
れ、且つ該密着シール部が剥離可能なシールであること
を特徴とする医療用容器。1. A medical container having a connection portion for connecting another drug container to a main body of a resin container containing a drug solution, wherein a communication port in the connection portion is present in the main body, and a peripheral edge of the communication port is provided in the main body. A medical container characterized in that it is tightly sealed to a wall surface of the main body in a liquid-tight manner and is closed, and the tightly-sealed portion is a peelable seal.
ための剥離防止材を上記連通口が位置する本体の外壁面
に設けることを特徴とする請求項１に記載の医療用容
器。2. The medical container according to claim 1, wherein an anti-peeling material is provided on an outer wall surface of the main body where the communication port is located to maintain the close-contact seal portion in a non-peeling state.
られていることを特徴とする請求項１又は２記載の医療
用容器。3. The medical container according to claim 1, wherein said close contact seal is provided in two or more sections.
めの連通針が設けられ、該連通針と上記本体内に存在す
る連通口とが通じていることを特徴とする請求項１〜３
の何れかに記載の医療用容器。4. A communication device according to claim 1, wherein a communication needle for communicating with the inside of the medicine container is provided at the connection portion, and the communication needle and a communication port existing in the main body communicate with each other. 3
The medical container according to any one of the above.
フィルタと上記本体内に存在する連通口とが通じている
ことを特徴とする請求項１〜３の何れかに記載の医療用
容器。5. The medical device according to claim 1, wherein a sterilization filter is provided at the connection part, and the filter and a communication port existing in the main body communicate with each other. container.
けられ、上記薬剤容器は上記本体内の連通口と通じてい
ることを特徴とする請求項１〜３の何れかに記載の医療
用容器。6. The container according to claim 1, wherein the other drug container is already provided at the connecting portion, and the drug container communicates with a communication port in the main body. Medical container.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9144598A JPH10314273A (en) | 1997-05-19 | 1997-05-19 | Medical vessel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9144598A JPH10314273A (en) | 1997-05-19 | 1997-05-19 | Medical vessel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10314273A true JPH10314273A (en) | 1998-12-02 |
Family
ID=15365780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9144598A Pending JPH10314273A (en) | 1997-05-19 | 1997-05-19 | Medical vessel |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH10314273A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150005734A1 (en) * | 2011-12-29 | 2015-01-01 | Otsuka Pharmaceutical Factory, Inc. | Exposure prevention cover, exposure prevention cover module provided with same, drug solution supply system, and drug solution supply method |
| KR20180074767A (en) * | 2015-11-13 | 2018-07-03 | 충칭 루미 파마슈티컬 컴퍼니.,리미티드. | Pharmaceutical mix blender, rigid dual port and sap bag for infusion |
| KR20180075596A (en) * | 2015-11-13 | 2018-07-04 | 충칭 루미 파마슈티컬 컴퍼니.,리미티드. | Single Needle Mixing Mixer, Hard Dual Port and Soft Bag for Infusion |
-
1997
- 1997-05-19 JP JP9144598A patent/JPH10314273A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150005734A1 (en) * | 2011-12-29 | 2015-01-01 | Otsuka Pharmaceutical Factory, Inc. | Exposure prevention cover, exposure prevention cover module provided with same, drug solution supply system, and drug solution supply method |
| KR20180074767A (en) * | 2015-11-13 | 2018-07-03 | 충칭 루미 파마슈티컬 컴퍼니.,리미티드. | Pharmaceutical mix blender, rigid dual port and sap bag for infusion |
| KR20180075596A (en) * | 2015-11-13 | 2018-07-04 | 충칭 루미 파마슈티컬 컴퍼니.,리미티드. | Single Needle Mixing Mixer, Hard Dual Port and Soft Bag for Infusion |
| JP2018533457A (en) * | 2015-11-13 | 2018-11-15 | 重慶莱美薬業股▲ふん▼有限公司Ｃｈｏｎｇｑｉｎｇ Ｌｕｍｍｙ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．，Ｌｔｄ． | Single needle drug mixer, hard dual interface and infusion softback |
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