JPH10279407A - Fungicide-containing aerosol and fungicide-containing solution - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a fungicide-containing aerosol and a fungicide-containing solution which can be used all over the pH range and contains the fungicides capable of controlling the propagation of any kind of fungi without limitation. SOLUTION: In the fungicide-containing aerosol comprising a polar solvent, an aerosol propellant and a fungicide as essential components, thiazolsulfamide compound is used as a fungicide, the amount of the fungicide is 0.5-3.0 pts.wt. based on 100 pts.wt. of the polar solvent. In addition to the above component, one or more than two kinds of bactericide, binder, disperser adjuvant and deodorant are contained.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a fungicide-containing aerosol and a fungicide-containing liquid which are used by spraying or applying to a place where mold is generated.

[0002]

2. Description of the Related Art Heretofore, as a fungicide-containing aerosol and a fungicide-containing liquid, there have been used those using 2- (4-thiazolyl) -benzimidazole (TBZ) as a fungicide.

[0003]

However, aerosols and the like using TBZ as a fungicide are not sufficient in sustainability, and the types of mold that can prevent reproduction are limited. .

Furthermore, TBZ has a narrow usable pH range, cannot be used in a strong acid range or a strong alkali range, and has no resistance to algae.

In view of the above, the present invention relates to any p
It is an object of the present invention to provide a fungicide-containing aerosol and a fungicide-containing liquid that contain a fungicide that can be used in the H region and that is not limited in the type of mold capable of preventing propagation.

[0006]

The present invention solves the above-mentioned problems by the following constitutions.

(1) In a fungicide containing a fungicide comprising a polar solvent, a propellant and a fungicide as essential components, the fungicide is a thiazolylsulfamide compound, and the fungicide is a polar solvent 100 0.5-3.
0 parts by weight, in addition to the above components, an antibacterial agent, a binder,
It is characterized by containing one or more of a dispersing aid and a deodorant.

(2) In a fungicide-containing foam aerosol comprising water, a cleaning component, a propellant and a fungicide as essential components, the cleaning component is a mixture of a surfactant, a base component and a polar solvent. The fungicide is a thiazolylsulfamide compound, and the fungicide is added to 100 parts by weight of water.
1.0 to 5.0 parts by weight, and a cleaning component of 5.0 to 5 parts by weight.
It is characterized by containing 0.0 parts by weight, and containing 3.0 to 10.0 parts by weight of a propellant.

(3) In the fungicide-containing liquid containing a polar solvent, a surfactant and a fungicide as essential components, the fungicide is a thiazolylsulfamide compound. 5. The surfactant is contained in an amount of 3 to 1.0 part by weight, and
It is characterized by containing 0 to 20.0 parts by weight.

In (3), it is also possible to use water or a lower alcohol as a polar solvent.

Also, in addition to the component (3), a binder and a propellant may be blended to form an aerosol.

(4) In a fungicide-containing liquid containing a polar solvent, a fungicide and a polyhydric alcohol as essential components, the polar solvent is a mixture of water and a lower alcohol, and the lower alcohol is used in an amount of 5.0 to 5.0. Containing 40.0 parts by weight of a fungicide,
A thiazolyl sulfamide-based compound, a fungicide,
0.3 to 1.0 part by weight, and polyhydric alcohol
It contains 0 to 15.0 parts by weight, and contains an acid component or a base component in addition to the above components.
Is 3 or less or 12 or more.

[0013]

DESCRIPTION OF THE PREFERRED EMBODIMENTS One embodiment of the present invention will be described below in detail.

In the following, blending units are weight units unless otherwise specified.

(1) First, a fungicide-containing aerosol according to a first embodiment of the present invention will be described. The fungicide-containing aerosol comprises a polar solvent, a propellant and a fungicide as essential components, and the fungicide is a thiazolylsulfamide compound, an antibacterial agent, a binder, a dispersing aid and It contains any one or more of deodorants.

As the polar solvent, a lower alcohol having 1 to 4 carbon atoms such as methanol, ethanol and isopropanol is preferably used, and denatured ethanol such as 99 ° brucine-denatured ethanol and geraniol-denatured ethanol is also used. It is possible. Of these,
It is desirable to use ethanol or denatured ethanol.

As a propellant, liquefied petroleum gas (LP)
G), Freon 134a, dimethyl ether (DME) and the like can be used, and a compressed gas such as carbon dioxide gas and nitrogen gas can also be used. These propellants can be used alone or in combination of two or more.

Since LPG and DME are easily flammable and Freon 134a, carbon dioxide gas and nitrogen gas are hardly flammable, it is preferable to use different propellants depending on the application.

The mixing amount of the propellant is not particularly limited, but from the viewpoint of the internal pressure, the internal pressure is usually 35%.
2 to 8 kgf / cm ² (preferably 3 to 7 kgf / cm 2)
² ) Adjust so that it becomes.

As the thiazolyl sulfamide compound as a fungicide, "NACS" manufactured by Japan Applied Chemical Industry Co., Ltd.
It is preferable to use series, of which,
It is preferable to use “NA-1” which is a powder. The amount of the fungicide is 0.5 parts with respect to 100 parts of the polar solvent.
To 3.0 parts (preferably, 0.5 to 1.0 parts).

The antibacterial agent that can be added to the fungicide-containing aerosol of the present embodiment includes an inorganic silver-based antibacterial agent. Specifically, a very small amount of silver ions is bonded to a phosphate-based ceramic. And antimicrobial ceramics. The compounding amount of the antibacterial agent is 1.0 to 3.0 parts (preferably 1.0 to 1.5 parts) based on 100 parts of the total amount of the polar solvent and the fungicide. By adding an antibacterial agent, it is possible to impart not only mold but also bacteria resistance.

Examples of the binder include water-insoluble resins. Among them, it is preferable to use an acrylic resin such as an alkanolamine acrylate solution or an acrylate copolymer. Specifically, it is preferable to use “Plus Size L” series manufactured by Ryo Kagaku Kogyo. It is preferable to use "-2". The amount of the binder is 0.1 to 50.0 parts (preferably, 100 parts with respect to the total amount of the polar solvent and the fungicide).
0.5 to 30.0 parts). The blending amount is 0.
If the amount is less than 1 part, the coating film may be too thin and easily peeled off from the coating surface. In addition, the compounding amount is 5
If the amount is more than 0.0 part, when applied, dust or dirt easily adheres to the application surface and impairs the appearance, and when an aerosol is used, the buttons and valves are likely to be clogged, and the jetting may not be performed well. Because there is.

The addition of this binder makes it difficult for the fungicide to separate from the surface to be coated, thereby further improving the durability of the fungicide action. In addition, the "plus size CB"
-2 "has no tackiness and has a property of being highly water-resistant, so that if it is used as a binder, it is suitable for use around water in bathrooms and kitchen sinks where mold can easily propagate. is there.

As the dispersing aid, silane compounds such as alkoxysilane and chlorosilane are preferable. In particular,
It is preferable to use alkoxysilanes manufactured by Toshiba Silicone Co., and among them, particularly, “TSL8177”
It is preferable to use (diphenyldiethoxysilane). The mixing amount of the dispersing agent is 5.0 parts or less (preferably 1. parts) with respect to 100 parts of the total amount of the polar solvent and the fungicide.
0 or less).

By incorporating this dispersing aid, the fungicide and the like are hardly settled in the aerosol can, and when spraying, the dispersing ability of the fungicide and the like is enhanced, and the effect on the entire coated surface is improved. It is possible to exert.

Further, as the deodorant, an aromatic deodorant, a natural vegetable deodorant and the like can be used. Specifically, it is preferable to use "FS-500A" manufactured by Niimatsu Shinyaku Co., Ltd. The compounding amount of the deodorant is 2.0 to 5.0 parts (preferably 2.0 to 2.5 parts) based on 100 parts of the total amount of the polar solvent and the fungicide. . By blending a deodorant, the odor is instantly removed,
Since it is possible to alleviate the discomfort and to suppress the growth of the odor source, it is suitable for use in grated boxes, shoes, sports equipment, and the like.

These antibacterial agents, binders, dispersing aids and deodorants may be added alone or in admixture of two or more. In addition to these additives, it is also possible to add a fragrance, a bactericide and the like.

(2) Next, a second embodiment of the present invention will be described. The fungicide-containing foam aerosol comprises water, a cleaning component, a propellant and a fungicide as essential components, and the cleaning component is a mixture of a surfactant, a base component, and a polar solvent. Is “NA-1”.

The water that can be used in the present embodiment is not particularly limited, and examples thereof include distilled water and purified water.

Examples of the surfactant used in the cleaning component include a nonionic surfactant, an anionic surfactant, an amphoteric surfactant and the like. Among these, nonionic surfactants have high hydrophilicity and HLB (hydrophile
It is desirable to use one having a relatively high detergency, with a value of -lipophile balance in the range of 13-15. In the present embodiment, these surfactants can be used alone or in combination of two or more. The amount of the surfactant varies depending on the type of the surfactant, but is usually 0.05 to 4.0 parts (preferably 0.1 to 100 parts) per 100 parts of the cleaning component.
3.5 parts). Below, surfactants that can be used,
Each is exemplified.

Nonionic surfactants: glycerin fatty acid ester, polyglycerin fatty acid ester, polyethylene glycol fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene sorbite fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene fatty acid amide ester , Sucrose fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether,
Polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, and the like.

Anionic surfactants: fatty acid salts, alkyl sulfates, polyoxyethylene alkyl ether sulfates,
Alkyl sulfonate, N-acyl sulfonate, alkyl phosphate, N-acyl amino acid salt, alkyl ether carboxylate, N-acylmethyl taurine salt, polyoxyethylene alkyl ether acetate, polyoxyethylene alkyl ether phosphorus Acid, polyoxyethylene alkyl ether phosphate, etc.

Amphoteric surfactants: betaine-type amphoteric surfactants such as carboxybetaine, sulfobetaine and betaine acetate, and imidazoline-type amphoteric surfactants.

Examples of the polar solvent used for the washing component include water such as purified water and distilled water, lower alcohols having 1 to 4 carbon atoms, alcohols such as glycols, ketones and esters. Species or a mixture of two or more species can be used, and among these, water, lower alcohols and glycols are preferably used. In particular, lower alcohols are suitable for use such as methanol, ethanol and isopropanol, and glycols are suitable for use such as ethylene glycol and propylene glycol, and derivatives of glycols such as methyl cellosolve, ethyl cellosolve and butyl cellosolve. Are also suitable for use. The amount of the polar solvent is not particularly limited, and may vary depending on the type of the solvent.
3.0 to 99.0 parts (preferably 5.0 to 96.0 parts)
Part).

Examples of the base component used in the washing component include hydroxides, phosphates and silicates of alkali metals such as sodium and potassium, ammonium salts, and alkanolamines such as triethanolamine. No. By adding this base component, the cleaning component is adjusted to have a pH of 9 to 14.

When the pH of the washing component is made weakly basic, that is, 9 or more and less than 12, a fungicide-containing foam aerosol which is preferably used in ordinary households is obtained.
When H is made to be 12 or more strongly basic, it can be used for heavily soiled portions, and thus can be used for business use or the like.

The amount of "NA-1" is 1.0 to 5.0 parts (preferably 1.0 to 3.0 parts) per 100 parts of water.
Part).

(3) Next, a colorless and transparent fungicide-containing liquid according to a third embodiment of the present invention will be described. The fungicide-containing liquid contains a polar solvent, a surfactant and a fungicide as essential components, and the fungicide is “NA-1”.
It is.

As the polar solvent, it is possible to use water such as purified water or distilled water, or the lower alcohols exemplified in the first embodiment.

As the surfactant, it is desirable to use an anionic surfactant among the surfactants of the second embodiment described above, and it is particularly preferable to use polyoxyethylene alkyl ether phosphoric acid. Specifically, Nikko Chemicals'"DDP-2","DNPP-4",
It is preferable to use "DDP-10" or the like. These surfactants may be used alone or in combination of two or more. The amount of the surfactant is 6.0 to 20.0 parts (preferably 10.2 parts).
0 to 14.0 parts). If the amount is less than 6.0 parts, the solution becomes a suspension solution, and a transparent fungicide-containing liquid cannot be obtained.

The amount of "NA-1" is 0.3 to 1.0.
Parts (preferably 0.5 to 0.7 parts).

Further, in addition to the above components, a binder and a propellant may be blended to obtain a fungicide-containing aerosol.

As the binder, the same binders as those usable in the first embodiment described above can be used, and the amount of the binder is the same as in the first embodiment.

As the propellant, DME is preferably used from the viewpoint of compatibility with the obtained fungicide-containing liquid.

(4) Next, a colorless and transparent fungicide-containing liquid according to a fourth embodiment of the present invention will be described. The fungicide-containing liquid contains a polar solvent, a fungicide, and a polyhydric alcohol as essential components, and the fungicide is “NA-1”. In addition to the above components, an acid component or a base component is added. It contains.

As the polar solvent, a mixture of water and a lower alcohol can be used, and the usable water and lower alcohol are the same as those usable in the above embodiment. Of these, the compounding amount of the lower alcohol is 5.0 to 40.0 parts (preferably 10.0 to 3 parts).
0.0 parts). If the amount is less than 5.0 parts, the generated fungicide-containing liquid may not be colorless and transparent, and if it is more than 40.0 parts, “NA-1” may be precipitated. It is.

As polyhydric alcohols, glycerin,
Examples thereof include 1,3-butylene glycol, polyethylene glycol, ethylene glycol, and propylene glycol. Among them, it is particularly preferable to use ethylene glycol. The compounding amount of the polyhydric alcohol is 1.0 to 15 parts (preferably, 1.0 to 10 parts).
Part). If the amount is less than 1.0 part, the resulting fungicide-containing liquid may be colored.

The compounding amount of “NA-1” is 0.3 to 1.0 part (preferably 0.5 to
0.7 part).

As the acid component, inorganic acids such as hydrochloric acid, sulfuric acid, nitric acid and the like can be used, and among them, hydrochloric acid is particularly preferably used. In addition, as the base component, hydroxides, phosphates, silicates, and the like of alkali metals such as sodium and potassium, or ammonium salts can be used. Of these, sodium hydroxide is particularly preferable. Can be used. The acid component or the base component adjusts the pH of the fungicide-containing liquid, and is preferably added so that the pH of the solution is 3 or less or 12 or more. If the pH of the solution is higher than 3 and lower than 12, the resulting fungicide-containing liquid may not be colorless and transparent.

The fungicide-containing aerosol and the fungicide-containing liquid of the present invention are not particularly limited as long as the place where mold is likely to occur.
It can be used for all kinds of products such as water around kitchen sinks, filters for air conditioners, rugs, mats, carpets, tatami mats, rugs, shoes and other leather goods, sofas and other furniture, and sports equipment.

[0051]

The present invention will be described below in more detail with reference to Examples and Comparative Examples.

(1) The compositions of the fungicide-containing aerosols of Example 1 and Comparative Example 1 based on the first embodiment of the present invention are shown in Table 1, and Example 2 and Comparative Example 2 based on the second embodiment. Table 2 shows the compositions of the fungicide-containing foamed aerosols.

In Table 2, the following components were used as the cleaning components.
1. The pH of the mixed component of the linear component and the purified water is 12.68.
It is.

Cleaning component Nonionic surfactant 1.75 parts (polyoxyethylene alkyl phenyl ether) Anionic surfactant 0.90 parts (alkyl sulfate) Amphoteric surfactant 0.50 parts (Imidazoline type amphoteric surfactant) Agent) Sodium hydroxide 1.30 parts Potassium hydroxide 0.25 parts Glycols 1.00 parts Purified water 94.30 parts

[0055]

[Table 1]

[0056]

[Table 2]

The fungicide-containing aerosols obtained in Example 1 and Comparative Example 1 and the fungicide-containing foam aerosols obtained in Example 2 and Comparative Example 2 were MIL, respectively.
Modified method (MIL STD 810D Method 50)
8.3 Modification), a "mold resistance test" was performed. Each of the aerosols is spray impregnated on a paper disk as a test piece, and the test bacteria are inoculated by direct inoculation of a mixed spore suspension of the test bacteria by a wet method, and then cultured in an incubator for 28 days. The culture conditions in the incubator are as follows: temperature: 30 ° C. ± 5 ° C. (24-35 ° C. during conversion)
Humidity: 95% ± 5% RH (90% RH or more during conversion), wind speed: 60 cm / sec.

The test bacteria to be inoculated were 6 ° C. ±
Pure cultures of stock culture stored at 4 ° C. within 30 days and test subcultures were used. The types of test bacteria are shown below.

Nigrospora oryzae, Cladosporium Regine, Cladosporium Herbalem, Cladosporium Cladosporioidas, Cladosporium
Safaerosperma, Trichoderma koningi, Trichoderma T-1, Trichoderma viridi, Forma
Gromelata, Former Terescias, Pluraria Pullance, Gliocradium Wilens, Geotricum Lactas, Geotricum Candidum, Pestalozia Adasta, Pestalozia Neglecta, Milotesium Fercaria, Alternaria Teners, Alternaria Brassicola, Alternaria Gusteria Algherias Pergersperger, Spelling , Aspergillus felicicor, Aspergillus oryzae, Aspergillus terreus, Aspergillus fumigatus, Aureobasidium pullulans, Fusarium moniliforme, Fusarium semitectam, Fusarium praliferatum, Fusarium roseum, Fusarium solani, Fusarium sulphosporisol sulphosporis prisrum Roniferu, Penicillium citrinum, Penicillium
Ikupansa, Penicillium funiculosam, Penicillium relacinum, Penicillium nigricans, Penicillium frequentas, Penicillium citreobility, Mucor racemassas, Eurotium tonaphyram, Trichofetin mentagrophytes, Monilia fructtigana, Ketomium clocamium Globoscum globacium Cola, Waremia Sebi, Candida albicans, Streptofetecilium reticalem, Saccharomyces cerevisiae, Bacillus subtilis, Bacillus megaterium, Staphylococcus ole, Pseudomonas eruginosa, Pseudomonas fullescens, Salmonella typhimariae, Esproetrichae cholera esculentes Squirrel.

Table 3 shows the test results.

The evaluation is made in five steps.
The criteria are as follows.

0: No growth of bacteria was observed at all 1: Slight growth was observed 2: Slight growth was observed 3: Intermediate growth was confirmed 4: Vigorous growth was observed

[0063]

[Table 3]

The results shown in Table 3 indicate that the test pieces impregnated with the aerosols of Examples 1 and 2 by spraying showed no growth of bacteria even after 28 days.

(2) The compositions of the fungicide-containing liquids of Examples 3 to 5 and Comparative Examples 3 to 5 based on the third embodiment of the present invention are shown in Table 4, and the fungicides of Example 3 and Comparative Example 3 are shown. Table 5 shows the compositions of the fungicide-containing aerosols of Example 6 and Comparative Examples 6 to 8 in which a binder and a propellant were mixed with the agent-containing liquid.

[0066]

[Table 4]

[0067]

[Table 5]

Examples 3 to 5 and Comparative Examples 3 to 5 show that when the amount of the surfactant is small, the resulting solution becomes a suspension. Further, from Example 6 and Comparative Examples 6 to 8, it is found that if the amount of the binder is too small, the coating film becomes sticky, and if the amount is too large, clogging occurs during aerosol injection.

(3) Table 6 shows the compositions of the fungicide-containing liquids of Examples 7 to 10 based on the fourth embodiment of the present invention. In Examples 7 and 8, an aqueous solution of sodium hydroxide was used.
In the case of 0, the pH is adjusted by adding hydrochloric acid.

[0070]

[Table 6]

[0071]

The function and effect of the fungicide-containing aerosol and the fungicide-containing liquid of the present invention are as described above.
The following functions and effects are achieved.

By using a thiazolyl sulfamide compound as a fungicide, it can be used in all pH ranges, and the type of fungus capable of preventing propagation is not limited. A liquid is obtained.

The fungicide-containing aerosol and the fungicide-containing liquid of the present invention can be used in a strong acid region and a strong alkali region. It can also have a dropping action.

Since the thiazolyl sulfamide compound also has resistance to algae, the fungicide-containing aerosol and the fungicide-containing liquid of the present invention can be used around water in bathrooms, toilets, kitchen sinks and the like. In this case, an anti-algal effect is also obtained.

Furthermore, various effects can be added by blending an antibacterial agent, a binder, a dispersing aid, a deodorant, and the like.

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[Procedure amendment]

[Submission date] April 23, 1997

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0026

[Correction method] Change

[Correction contents]

Further, as the deodorant, an aromatic deodorant,
Natural vegetable deodorants and the like can be used. Specifically, it is preferable to use "FS-500A" manufactured by Shirai Matsushin Pharmaceutical Co., Ltd. The compounding amount of the deodorant is 2.0 to 5.0 parts (preferably 2.0 to 2.5 parts) based on 100 parts of the total amount of the polar solvent and the fungicide. . By blending a deodorant, the odor is instantly removed,
Since it is possible to alleviate the discomfort and to suppress the growth of the odor source, it is suitable for use in grated boxes, shoes, sports equipment, and the like.

[Procedure amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0053

[Correction method] Change

[Correction contents]

The cleaning components in Table 2 include:
Using the composition shown below, in Table 2, NA-
1. The pH of the mixed component of the washing component and the purified water is 12.68.
It is.

Claims (6)

[Claims] 1. A fungicide containing a fungicide comprising a polar solvent, a propellant and a fungicide as essential components, wherein the fungicide is a thiazolyl sulfamide compound, and For 100 parts by weight of the solvent,
0.5 to 3.0 parts by weight, and in addition to the above components, one or more of an antimicrobial agent, a binder, a dispersing aid, and a deodorant are contained. Aerosol containing fungicide. 2. A fungicide-containing foam aerosol comprising water, a cleaning component, a propellant and a fungicide as essential components, wherein the cleaning component is a mixture of a surfactant, a base component and a polar solvent, The fungicide is a thiazolyl sulfamide compound, and the fungicide is added in an amount of 1.0 to 100 parts by weight of the water.
0.5 to 5.0 parts by weight; 5.0 to 50.0 parts by weight of the cleaning component; and 3.0 to 10.0 parts by weight of the propellant. Contains foam aerosol. 3. A fungicide-containing liquid comprising a polar solvent, a surfactant and a fungicide as essential components, wherein the fungicide is a thiazolylsulfamide-based compound; 3. A colorless and transparent fungicide-containing liquid containing from 3 to 1.0 part by weight, and containing from 6.0 to 20.0 parts by weight of the surfactant. 4. The fungicide-containing liquid according to claim 3, wherein water or a lower alcohol is used as the polar solvent. 5. The fungicide-containing aerosol according to claim 4, wherein a binder and a propellant are blended to enable injection. 6. A fungicide-containing liquid containing a polar solvent, a fungicide and a polyhydric alcohol as essential components, wherein the polar solvent is a mixture of water and a lower alcohol, and the lower alcohol is 5.0. The fungicide is a thiazolyl sulfamide-based compound; the fungicide is contained in an amount of 0.3 to 1.0 part by weight; 0.01 to 15.0 parts by weight, containing an acid component or a base component in addition to the above components, wherein the fungicide-containing liquid has a pH of 3 or less or 12 or more. Transparent fungicide-containing liquid.