JPH0977643A - Aerosol hair growing composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an aerosol hair growing composition excellent in a feeling in use (liquid dripping, etc.) usable to the last. SOLUTION: This aerosol hair growing composition comprises a nonaqueous or hydrous lower alcohol hair growing agent preparation and a compressed gas as main components and has 5-1,000cp viscosity of a stock solution of the composition, (a) a spray pattern (10cm apart): 1-20cm and (b) a sprayed amount (10 seconds): 5-10g.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a feeling of use (liquid sagging, etc.)
The present invention relates to an aerosol hair-growth composition having excellent usability, and more particularly, to an aerosol hair-growth composition containing a non-aqueous or hydrous lower alcoholic stock solution as a compound having a cell activating activity (a compound having a hair-growth activity).

[0002]

2. Description of the Prior Art Aerosol type hair restorers can be easily used and have a good feeling in use, and are commercially available from various companies. Recently, it has been found that the CFC gas used as an aerosol propellant destroys the ozone layer, and in order to protect the global environment, the development of a CFC alternative gas has been actively carried out.

A technique for making an undiluted solution of an active ingredient dissolved or dispersed in a non-aqueous or hydrous lower alcohol by a combustible gas or a compressed gas into an aerosol is disclosed in JP-A-51-11618.
5, JP-A-59-64688 and JP-A-54-321.
85, JP-A-60-1131, and JP-A-60-149.
No. 514, JP-A-2-180808 and the like are known. Further, as a technique including a combustible gas or a compressed gas for pressure adjustment, JP-A-55-142073, JP-A-57-18776, and JP-A-57-18776 are known. Known are Kaikai 57-34172 and the like.

By the way, in the conventional aerosol type hair restorer, since the liquid directly reaches the scalp from a position slightly away from the hair, liquid dripping is likely to occur immediately after spraying. However, as techniques for preventing dripping, which is a drawback of such aerosol hair-growth agents, there are known techniques such as JP-A-5-262621, JP-A-6-100060, and JP-A-7-101834. Therefore, it cannot always be said that both the feeling of use and the usability of the hair restorer are satisfied together with the prevention of dripping. Therefore, with regard to the aerosol composition of the non-aqueous or water-containing lower alcohol hair restorer, dripping can be prevented, it can be used directly on the scalp easily and easily, and the scalp can be comfortably touched (a refreshing feeling can be actually felt), and In reality, it is desired to have good usability (can be used to the end without clogging even at low temperature).

[0005]

DISCLOSURE OF THE INVENTION An object of the present invention is to provide an aerosol composition of a non-aqueous or water-containing lower alcohol hair growth stimulant which both prevents dripping and satisfies both feeling and usability.

[0006]

The aerosol hair-growing composition of the present invention comprises a non-aqueous or hydrous lower alcohol hair-growing preparation and a combustible gas and / or compressed gas as main components, and has a stock solution viscosity of 5 to 1000 cp. Therefore, a) spray pattern (away from 10 cm): 1 to 20 cm, b) spray amount (10 seconds): 5 to 10 g.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The undiluted solution as used in the present invention means a solution containing a lower alcohol and an active ingredient, or a solution containing water added thereto. Here, the content of the lower alcohol is 5 to 99.5% by weight. The content of the active ingredient is 0.01 to 30% by weight.

[0008] The active ingredient used in the present invention is a useful ingredient having a specific function, such as hair growth, whitening, wrinkle improvement,
UV protection, sterilization, acne prevention, gray hair improvement, dandruff prevention,
Examples thereof include components having a medicinal effect function such as blood circulation promotion and components having functions such as hair styling, moisturizing, softness, and split ends prevention, and these can be used alone or in combination of two or more kinds.
The content of the active ingredient is 0.01 to 30% by weight, preferably 0.05 to 10% by weight. If it is less than 0.01% by weight, there is no effect, and if it exceeds 30% by weight, stable blending of the stock solution becomes difficult and it tends to become sticky.

As the lower alcohol, methanol having 1 to 3 carbon atoms, ethanol, propanol and the like, preferably ethanol is used. This lower alcohol is used in anhydrous or hydrous form. The amount is preferably such that the active ingredient can be dissolved or dispersed and can be more stably compounded. The amount varies depending on the kind of the active ingredient, but preferably 40% by weight or more of ethanol in the total composition is used. .About.99.5% by weight, preferably 40 to 99.
5% by weight. If the amount is less than 5% by weight, the active ingredient will not dissolve.

Combustible gas is used as a propellant, and specifically, liquefied petroleum gas (LPG), dimethyl ether (D
ME) etc. are used alone or in combination of two or more kinds. The amount used is a weight ratio, and the undiluted solution: combustible gas is 95: 5 to 70:30, preferably 95: 5 to 85:
It is 15. Further, the aerosol composition of the present invention comprises nitrogen,
The pressure of compressed gas such as carbon dioxide and oxygen is adjusted to 4.0 to 7.
0 kg / cm ² · G / 20 ° C., preferably 4.5 to 6.
It can be adjusted to 5 kg / cm ² · G / 20 ° C.
If it is less than 4.0 kg / cm ² · G / 20 ° C., the pressure is too low to obtain a good feeling until the end. On the other hand, 7.0
At kg / cm ² · G / 20 ° C or higher, the danger at high temperatures and the degree of contact of the aerosol composition with the scalp are strong, resulting in poor usability.

When LPG is used as the combustible gas, the pressure is preferably less than 2.5 to 5 kg / cm ² · G / 20 ° C., and if the pressure is higher than this, the dischargeability deteriorates.

Other components of the hair-growing aerosol composition of the present invention include anionic, cationic, amphoteric, nonionic and other active agents, higher alcohols, hydrocarbons, natural fats and oils, ester oils, lipid derivatives, polyhydric alcohols and higher fatty acids. ,
Organic acids such as succinic acid and citric acid, amino acids such as glycine and glutamic acid and their derivatives, vitamins A and B
C / D / E and the like or derivatives thereof, crude drug extracts containing flavanols, arkanoids, terpenes, saponins, etc.,
Coloring agents, fragrances and the like can be mentioned.

The preferred embodiments of the present invention are as follows. (1) A non-aqueous or hydrous lower alcohol hair growth product and a flammable gas and / or a compressed gas as main components, the undiluted solution viscosity is 5 to 1000 cp, and a) spray spray pattern (away from 10 cm): 1 to 20 cm, b) Injection amount (10 seconds): 5 to 10 g, c) Combustible gas is liquefied petroleum gas or dimethyl ether, and d) undiluted liquid / combustible gas and / or compressed gas (nitrogen, oxygen, carbon dioxide gas) Etc.) in a weight ratio of 99.7 / 0.3 to 70/30, and (2) non-aqueous or hydrous lower alcohol hair growth preparation and compressed gas (nitrogen, oxygen). , Carbon dioxide gas, etc.) as the main component, optionally containing a flammable gas, and having a stock solution viscosity of 5 to 1000 cp, a) injection spray pattern (away from 10 cm): 1 to 20 cm, b). Injection amount (10 seconds): 5 to 1
0 g, (c ') the vapor pressure of the gas containing at least the compressed gas is 4.0 to 7.0 kg / cm ² · G / 20 ° C, d) the weight ratio of the stock solution / the gas containing at least the compressed gas is 99.7 /
The aerosol hair-growing composition, which is 0.3 to 70/30.

The aerosol hair-growth composition of the present invention is used by filling it into a pressure resistant container. Although various types of pressure-resistant containers (aerosol containers) are used, the container has a head having a through hole with a diameter of 0.1 to 2 mm at the tip of the container, and the top of the head is the scalp. It is desirable to use a hair-growth composition of a type that is applied and squeezes the scalp with some force so that the hair-growth composition is ejected from a through hole provided in the head. A preferable example of the head in such a container is one in which the inside is hollow and the cross section has a mortar-like shape as a whole, and the hair-growth composition has an ejection port (through hole) at the center of the recessed surface.

When the head of such an aerosol container is pressed against the scalp, at least all or most of the peripheral edge of the head is in contact with the scalp almost irrespective of the position of the scalp. In contrast, the recessed surface of the head may or may not contact the scalp. However, in any case, since the peripheral edge of the head surely contacts the scalp, there is no room for dripping.

[0016]

Next, the present invention will be described more specifically with reference to examples and comparative examples. Note that% here is based on weight.

Examples 1 and 2 and Comparative Examples 1 to 4 Aerosol hair-growing agents having the compositions shown in Table 1 were prepared, and the feeling and usability shown below were evaluated. (1) Liquid sagging 20 users of hair restorer used each sample and sensory evaluated the liquid sagging. ◯: 80% or more does not drip. ○ to △: 60 to 80% does not drip. (Triangle | delta): 40-60% does not drip. X: Less than 40% does not drip. (2) Feeling of Scalp Contact Twenty hair restorer users used each sample and sensory evaluated the feeling of hitting the scalp. ○: 80% or more is comfortable to touch ○ to △: 60 to 80% is comfortable to hit △: 40 to 60% is comfortable to hit ×: Less than 40% is comfortable to hit (3) At low temperature Clogging amount (jetting property, discharging property) Each sample shown in Table 1 is stored at 45 ° C for 2 days, then stored at 5 ° C for 1 day, and jetted for 10 seconds. This was repeated 10 times, and then the clogging amount was evaluated. ○: No clogging, same as in initial use ○ to △: Some clogging, slightly inferior jetting property △: Quite clogging, almost no ejection ×: Severe clogging, no ejection at all

[0018]

[Table 1]

Example 3 (Preparation of hair tonic agent) Dipotassium glycyrrhizinate 0.2% Carrot extract 0.1% Pantothenyl ethyl ether 0.1% Octopirox 0.05% Vitamin E derivative 0.2% POE ( 20) Glyceryl monoisostearate 0.5% Glycerin 2.0% 1-Menthol 0.2% Aloe extract 0.1% Carboxyvinyl polymer 0.1% Triisopropanolamine 0.2% Perfume Trace amount Pigment Trace amount Purified water 20.0% ethanol balance This was used as a stock solution (viscosity 300 cp / 20 ° C.), and an aerosol tonic agent of stock solution / propellant (LPG / DME = 90/10) = 70/30 (weight ratio) was prepared.・ The scalp had good comfort and clogging.

Example 4 (Preparation of hair restorer) Carpronium chloride 0.3% Biotin 0.03% Photosensitizer 301 0.01% Hinokitiol 0.1% Isopropylmethylphenol 0.1% Ethinyl estradiol 0.005% POE ( 40) Hardened castor oil 0.7% Polyethylene glycol 1.5% Hydroxyethyl cellulose 0.5% Fragrance Trace amount ethanol 40.0% Purified water The balance This is used as a stock solution (viscosity 700 cp / 20 ° C), and a stock solution / propellant (LPG) = 90/10 (weight ratio), 6 kg / G · 20 ° C aerosol hair nourishing agent was prepared with carbon dioxide, and as a result, liquid dripping, scalp contact comfort, and clogging were all good.

Example 5 (Production of hair growth agent) Minoxidil 1.0% Pentadecanol 1.5% Capsicum tincture 0.03% Glycyrrhetinic acid 0.2% Tocotrienol 0.2% Methylhydroxypropyl cellulose 0.3% 1,3-Butylene glycol 2.0% Succinic acid 0.1% Perfume 0.2% Ethanol 60.0% Purified water The rest is used as a stock solution (viscosity 500 cp / 20 ° C), and the stock solution is nitrogen gas at 6 kg / G. As a result of preparing the aerosol hair nourishing agent at 20 ° C., it was found that the liquid dripping, the contact feeling on the scalp and the clogging property were good.

[0022]

According to the invention of claim 1, it is possible to obtain an aerosol hair-growth agent which satisfies both feeling and usability without causing dripping.

Claims (1)

[Claims] 1. A non-aqueous or hydrous lower alcohol hair growth product and a flammable gas and / or a compressed gas as main components, and the undiluted solution viscosity is 5 to 1000 cp, and a) a spray pattern (away from 10 cm). ): 1-20 cm,
b) Spray amount (10 seconds): 5 to 10 g, an aerosol hair growth composition.