JPH09506300A - Multilayer barrier film for fistula applications - Google Patents

Multilayer barrier film for fistula applications

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Publication number
JPH09506300A
JPH09506300A JP50977395A JP50977395A JPH09506300A JP H09506300 A JPH09506300 A JP H09506300A JP 50977395 A JP50977395 A JP 50977395A JP 50977395 A JP50977395 A JP 50977395A JP H09506300 A JPH09506300 A JP H09506300A
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JP
Japan
Prior art keywords
layer
film
water
soluble
thermoplastic polyurethane
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JP50977395A
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Japanese (ja)
Inventor
アレン，スコット・アイ
フォイ，デウェイン・エフ
ファーガソン，マイケル
Original Assignee
ザ・ダウ・ケミカル・カンパニー
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Publication of JPH09506300A publication Critical patent/JPH09506300A/en
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
    • A61F5/445—Colostomy, ileostomy or urethrostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L28/00—Materials for colostomy devices
    • A61L28/0061—Materials for coating
    • A61L28/0069—Macromolecular materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/40—Layered products comprising a layer of synthetic resin comprising polyurethanes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/30—Properties of the layers or laminate having particular thermal properties
    • B32B2307/31—Heat sealable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/716—Degradable
    • B32B2307/7166—Water-soluble, water-dispersible
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/724—Permeability to gases, adsorption
    • B32B2307/7242—Non-permeable
    • B32B2307/7244—Oxygen barrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/724—Permeability to gases, adsorption
    • B32B2307/7242—Non-permeable
    • B32B2307/7246—Water vapor barrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2375/00—Polyureas; Polyurethanes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2535/00—Medical equipment, e.g. bandage, prostheses, catheter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1334—Nonself-supporting tubular film or bag [e.g., pouch, envelope, packet, etc.]
    • Y10T428/1341—Contains vapor or gas barrier, polymer derived from vinyl chloride or vinylidene chloride, or polymer containing a vinyl alcohol unit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
    • Y10T428/2813—Heat or solvent activated or sealable
    • Y10T428/2817—Heat sealable
    • Y10T428/2826—Synthetic resin or polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
    • Y10T428/2852—Adhesive compositions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y10T428/31573—Next to addition polymer of ethylenically unsaturated monomer
    • Y10T428/3158—Halide monomer type [polyvinyl chloride, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nursing (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Laminated Bodies (AREA)

Abstract

An oxygen and moisture impermeable multilayer barrier film is provided including a barrier layer comprising a homopolymer of vinylidene chloride or a copolymer of vinylidene chloride and vinyl chloride or methyl methacrylate. The barrier layer may be coated onto or coextruded with a water soluble film layer comprising a blend of a water soluble polymer such as polyvinyl alcohol, polycaprolactone, or polyethyloxozaline and a thermoplastic polyurethane. The multilayer film may be used for reusable or disposable ostomy bags and for heat sealable bags used in packaging agricultural chemicals, detergents, and other household chemicals.

Description

【発明の詳細な説明】 造瘻術用途のための多層遮断フィルム 本発明は、酸素及び水分不透過性の同時押出しされた又は塗布された多層遮断 フィルムに関するものであり、また前記多層遮断フィルムから製造される、様々 な材料を包装するための造瘻術用バッグ（ostomy bags）及びヒートシール可能 なバッグを含む製品に関するものである。 酸素及び水蒸気に対して遮断性を有するプラスチックフィルム積層品は、現在 の包装に要求されている条件にとって、ならびに医療用途おける使用、例えば造 瘻術用バッグの二次加工にとって望ましかった。前記フィルムは、層の少なくと も１つが酸素及び水蒸気に対して不透過性である多層フィルム積層品を用いるこ とによって提供されて来た。典型的には、前記フィルムは、塩素化ポリエチレン フィルム又は可塑化ポリ塩化ビニルフィルム、ポリ塩化ビニリデンコポリマーフ ィルム、又は多層構造、例えばエチレンビニルアセテート・ポリ塩化ビニリデン とエチレンビニルアセテートとを組み合わせたフィルムを含む。前記の構造は酸 素及び水分遮断性のニードを十分に満たすが、使用時に、しばしば、使用者にと って便利な方法で廃棄する（例えばバッグをトイレに流す）ことが難しかった。 Martiniらによる米国特許第４．９０６．４９５号は、造瘻術用途で用いられ る積層フィルムに関するものである。遮断層と水溶性層とは、追加の接着剤層を 用いて共に接着されなければならない。前記の追加層によって、材料及び製造コ ストが増加するだけでなく、より大きな剛性を有するより厚いフィルム積層品が 製造されてしまう。 Brookらによる米国特許第４，７７２，２７９号、及びCoombesらによる米国特 許第４，９１7，６８９号は、ポリビニルアルコールから成る水溶性外層と、ポ リ塩化ビニリデンから成る比較的不溶性の内層とを有する廃棄可能な造瘻術用バ ッグに関するものである。同様に、英国特許第２．０８３．７６２号及び第２． １９３，９２５号の双方は、水溶性層と遮断層とを含む廃棄可能な造瘻術用バッ グを説明している。 しかしながら、現行の従来技術による多層フィルムの多くは、ヒートシール可 能な表面を有していないので、例えば前記フィルムのほんの一部分の上に遮断層 を配置するというような、バッグを二次加工するための複雑な方法を必要とする 。さらに、多くの多層フィルムは、層が共に支え合うように、層を積層するため の接着剤を必要とする。したがって、追加の接着剤層及び積層工程を必要としな いより単純でより安価な従来の方法によって製造することができる多層遮断フィ ルムに対するニード、また水分及び酸素に対して不透過性であり、また臭気遮断 性を提供し、バッグなどを作るためのヒートシール可能な表面を有する多層遮断 フィルムに対するニードが依然として存在している。 本発明は、他の層を共に固定するための分離接着剤層を必要としない、同時押 出技術又は塗布技術によって製造することができる酸素及び水分不透過性多層遮 断フィルムを提供することによって上記ニードを満たすものである。本発明フィ ルムは、優れた層間接着性、優れた臭気遮断性、及びバッグを二次加工するため のヒートシール可能な表面を提供する。 本発明の１つの態様にしたがって、フィルム幅１インチ当たり少なくとも１． ０lb、好ましくは１．５lbを超えるヒートシール強度を有する酸素及び水分不透 過性多層遮断フィルムが提供された。「酸素不透過性」とは、フィルムが９０cc /m2/H・atm以下の酸素透過度を有していることを意味している。「水分不透過性 」とは、フィルムが５gm/m2/H以下の水蒸気透過度を有していることを意味して いる。 本発明の１つの態様では、造瘻術用途で用いるために、本発明フィルムは、水 溶性フィルム層と共に同時押出しされるか又は水溶性フィルム層上に塗布される 塩化ビニリデンのホモポリマー又はコポリマーから成る遮断層を含む。好ましく は、水溶性層は、水溶性ポリマー、例えばポリビニルアルコール、ポリカプロラ クトン、又はポリエチルオキソザリンと熱可塑性ポリウレタンとの配合物を含む 。好ましくは、水溶性層は、遮断層に比べて厚く、そして熱可塑性ポリウレタン を１−５０重量％、さらに好ましくは熱可塑性ポリウレタンを１０−２５重量％ 含む。水溶性フィルムは、単層であっても良く、又は水溶性ポリマーと熱可塑性 ポリウレタンとの配合物を含む第一層及び同じか又は異なる水溶性ポリマーを 含む第二層を有する２つ以上の層を含むことができ、それによってフィルムの水 溶性が向上する。 さらに、水溶性層と遮断層との間の接着は、多くの手段を用いて向上させるこ とができる。それらの手段としては、水溶性層に対して熱可塑性ポリウレタン層 を塗布又は同時押出しするか、又は接着を向上させる量の熱可塑性ポリウレタン を遮断層と配合することが挙げられる。得られるフィルムは９０cc/m2/H・atm未 満の酸素透過度を有する。遮断層は、内側に面している遮断フィルムで廃棄可能 バッグを作るために、それ自体に対してヒートシールするように配合された。 本発明のこの態様の別の形態では、さらに、遮断フィルムは、水溶性層の反対 側に例えば熱可塑性ポリウレタンを含む適当な接着剤樹脂から成る任意のヒート シール可能なスキン層を含むことができる。前記の層によって、フィルムに対し て向上したヒートシール性が提供される。 本発明の多層遮断フィルムは、追加の接着剤層を用いなくても、また層を積み 重ねずとも、同時押出し又は塗布することができるほど十分な結合を有する、こ とが発見された。さらに、得られるフィルムの特性は、廃棄可能な又は再使用可 能な造瘻術用パウチとして、ならびに農薬、洗剤、及び他の家庭用薬品用の包装 として用いるのに適している。 したがって、本発明の特徴は、同時押出法又は塗布法を用いて製造することが できる酸素及び水分透過性多層遮断フィルムを提供することであった。さらに、 本発明の特徴としては、臭気遮断性と、本発明フィルムから製造されるヒートシ ール可能なバッグ及びパウチを形成する能力が挙げられる。 図１は、水溶性層を含む廃棄可能な造瘻術用パウチとして有用な本発明の多層 遮断フィルムの１つの態様に関する概略断面図であり； 図２は、本発明の図１の多層遮断フィルムから作られた造瘻術用バッグ又はパ ウチに関する正面図であった。 本発明の多層遮断フィルムは、分離接着剤層又は分離グルー層を用いることを 必要とせずに、また積層時に行われる余分な製造工程に関連して生じる付随コス トを必要とせずに、従来技術による積層フィルムに比べて層間に対してより強い 接着を提供する。したがって、前記フィルムは、遮断フィルム材料を水溶性フィ ルム層の上に塗布する塗布法によって製造することができる。得られた多層フィ ルムは、低い酸素及び水蒸気透過度を有し、また造瘻術用途にとって必要とされ る臭気遮断性をも有する。本発明を実施することによって、追加の接着剤層を適 当に選択して用いなくても、またフィルムの各層の成分を配合しなくても、これ らの特性を達成することができる。 図１参照。層の厚さは正確な寸法の縮尺ではない。多層フィルム１０が、水溶 性フィルム層１２と共に同時押出しされるか又は前記層１２上に塗布される、塩 化ビニリデンのホモポリマー、あるいは塩化ビニリデンと塩化ビニル又はメチル メタクリレートとのコポリマーから成る遮断層１４を含む、造瘻術用途のための 本発明の１つの態様を図示した。好ましくは、水溶性層１２は、水溶性ポリマー 、例えばポリビニルアルコール、ポリカプロラクトン、又はポリエチルオキソザ リンと、熱可塑性ポリウレタンとの配合物を含む。水溶性層１２は、典型的には 、熱可塑性ポリウレタンを１−５０重量％、さらに好ましくは１０−２５重量％ 含む。所望ならば、追加の熱可塑性ポリウレタンを配合物に加えて、遮断層に対 する被膜の接着を向上させることができる。しかしながら、フィルムの水溶性は 、熱可塑性ポリウレタンの量が増加すると悪影響を受けるので、注意しなければ ならない。水溶性フィルムは配合物から成る１つの単層を含むことができるが、 この配合物を別の水溶性ポリマー樹脂と同時押出しして、向上した水溶性を有す る二層フィルムを製造することもできた。 適当な遮断材料としては、例えば、Saran（登録商標）Ｆ２７９という商標でD ow Chemical Companyから市販されている塩化ビニル（１５−２０重量％）と塩 化ビニリデン（８０−８５重量％）とのコポリマーが挙げられる。水溶性フィル ム層としては、水溶性ポリビニルアルコール樹脂、例えばAir Products and Che micals，Inc.から市販されているVinex（登録商標）５０３０樹脂を用いること ができる。向上した水溶性を有する二層フィルムが望ましい場合は、他の水溶性 ポリビニルアルコール樹脂、例えばVinex２１４４を用いることができる。２つ 以上の層を同時押出しすることができる。同時押出しする場合、２つの層の相対 的厚さを調節することができるので、フィルムの水への溶解性を制御することが できるという利点が得られる。例えば、未改質の水溶性ポリマー樹脂層は、向 上した水溶性を提供するための二層フィルムを７５％又はそれ以上まで含むこと ができる。 以上考察したように、熱可塑性ポリウレタン１−５０％を、ポリビニルアルコ ール又は他の水溶性ポリマー層と配合することができる。適当な熱可塑性ポリウ レタンとしては、ポリイソシアネート（芳香族又は脂肪族）と、ポリエステル、 ポリエーテル又はポリカプロラクトンポリオールとの反応に基づく熱可塑性ポリ ウレタンが挙げられる。連鎖延長剤、例えばジオール及びジアミンを前記反応に おいて用いることもできる。前記の熱可塑性ポリウレタンは、Estane（登録商標 ）という商標でB.F.GoodrichCo.から市販されており、またPellethane（登録商 標）という商標でDow Chemical Companyから市販されている。好ましい熱可塑性 ポリウレタン組成物はPellethane２３５５−９５ＡＥである。 図示したように、任意の熱可塑性ポリウレタンスキン層１６を、水溶性層１２ と共に同時押出しするか又は水性層１２上に塗布することができる。スキン層１ ６及び／又は水溶性層１２中に配合された熱可塑性ポリウレタンは、水溶性層１ ２に対する遮断層１４の接着を強める働きをする。得られるフィルムは、９０cc /m2/H・atm（６cc/100in2/H・atm）未満の酸素透過度を有しているべきである。こ のより高い酸素透過度は、廃棄可能であるように設計された遮断フィルムにとっ て許容できるものであった。図示したように、折り重ねてバッグ又はパウチを作 るときにフィルムに対して向上したヒートシール性を提供するために、多層フィ ルムは、水溶性層１２の反対側にあるフィルムの側面上に、ヒートシール可能な 材料、例えば熱可塑性ポリウレタン又は他の適当な接着剤樹脂から成る任意のス キン層１８を含むことができる。 図２は、図１の多層遮断フィルムから作られた開口部２６を含む典型的な廃棄 可能な造瘻術用バッグ２０を説明している。前記バッグは、多層フィルム１０の 縁を折り重ねて、その縁をヒートシールすることによって作ることができる。好 ましくは、遮断層及びヒートシール可能なスキン層によってバッグ又はパウチ２ ０の内面が提供されるように、フィルムを折り重ねてシールした。本発明の遮断 フィルムは、必要とされる防水性、臭気遮断性、及び酸素遮断性を有する容易に 廃棄可能な造瘻術用パウチを提供する。当業者によって評価されるように、本発 明の遮断フィルムは、水分及び酸素に対する遮断性が要求される他の包装用途に おいても、その利用を見出すことができる。 本発明の多層フィルムは、従来の押出技術又は塗布技術を用いて製造すること ができる。同時押出装置を用いるときには、押出ダイの形状を変化させて、各独 立層の厚さ及び寸法を減少させることができる。したがって、多層フィルムの厚 さを調節することができる。適当な塗布装置としてはグラビアコーターが挙げら れる。 同時押出の場合、水溶性フィルムの好ましい態様では、熱可塑性ポリウレタン の向上した接着性をポリビニルアルコール樹脂の優れた水溶性と組み合わせたと きに利点が得られた。前記の同時押出では、水溶性ポリビニルアルコール層を、 フィルムの全厚の７５％以上であるように厚くすることは好ましかった。典型的 には水溶性層は厚さ１−３ミルであり、遮断層は０．１−０．２ミルである。 しかしながら、多くの異なる層の組み合わせが可能であることを理解すべきで ある。例えば、フィルムは水溶性ポリマー／熱可塑性ポリウレタン配合物から成 る第一層、熱可塑性ポリウレタンから成る第二層、及び塩化ビニリデンホモポリ マー又はコポリマーを含む遮断層を含むことができる。別の可能な組み合わせと しては、水溶性ポリマー／熱可塑性ポリウレタン配合物、及び塩化ビニリデン／ 熱可塑性ポリウレタン配合物を含む遮断層を含む。さらに別の組み合わせは、水 溶性ポリマー／熱可塑性ポリウレタン配合物、熱可塑性ポリウレタンから成る層 、及びポリ塩化ビニリデン／熱可塑性ポリウレタン配合物を含む第三層を含む同 時押出しされた三層フィルムであった。なおさらに別の可能な組み合わせは、水 溶性ポリマー／熱可塑性ポリウレタン配合物を含む第一層、熱可塑性ポリウレタ ンを含む第二層、塩化ビニリデンホモポリマー又はコポリマーから成る第三層、 及び熱可塑性ポリウレタンから成る第四層を含む。 より容易に本発明を理解することができるように、以下に実施例を掲げた。下 記実施例は本発明の例証であり、発明の範囲を限定することを意図していない。 実施例１ まず最初に、４５−５０℃において、テトラヒドロフラン中に熱可塑性ポリウ レタン（Pellethane２３５４−８０Ａ５）５重量％を溶かして、本発明にした がって多層フィルムを製造した。次に、熱可塑性ポリウレタン（Pellethane２３ ５５−９５ＡＥ）を１０重量％含む押出しされた厚さ２．０ミルのポリビニルア ルコールフイルム（Air Products and Chemicals,Inc.から市販されているVinex ５０３０）の表面に塗布量２gm/m2で被膜を適用して、厚さ０．０５ミルにした 。そのコーテッドフィルムをオーブンの中に置いて、１２０℃で１．５分間乾燥 させた。 次に、テトラヒドロフラン６５重量％とトルエン３５重量％とを含む混合物中 にSaranF２７９を溶かすことによって、遮断材料の被膜を調製した。最終ラッカ ーはSaranを約１８重量％含んでいた。コーテッド水溶性フィルムの表面に塗布 量４gm/m2（厚さ約０．１ミル）で被膜を適用し、１１０℃で２分間乾燥させて 、溶媒を除去し、被膜を結晶化させた。得られた多層遮断フィルムは、３００° Ｆ、３０psi、１秒保圧で７．７Ｎ（１．７３lb）のヒートシール強度、および １３．９cc/m2/H・atmの酸素透過度を有していた。 実施例２ 水溶性フィルムがVinex５０３０を８５％及びPellethane２３５５−９５ＡＥ を１５％含んでいた以外は実施例１と同様にして、多層フィルムを調製した。得 られた多層遮断フィルムは、３００°Ｆ、３０psi、１秒保圧で９．９Ｎ（２． ２２lb）のヒートシール強度、および８．４cc/m2/H・atmの酸素透過度を有して いた。 実施例３ まず最初に、４５−５０℃において、テトラヒドロフラン中に熱可塑性ポリウ レタン（Pellethane２３５４−８０Ａ１）５重量％を溶して、本発明にしたがっ て多層フィルムを製造した。次に、Pellethane２３５５−９５ＡＥを１５重量％ 含む押出しされた厚さ２．０ミルのポリビニルアルコール樹脂（Air Products a nd Chemicals,Inc.から市販されているVinex５０３０）の表面に塗布量２gm/m2 で被膜を適用して、厚さ０．０５ミルとした。そのコーテッドフィルムをオーブ ンの中に置いて、１２０℃で１．５分間乾燥させた。 次に、最終ラッカーがSaranを約１８重量％及びPellethaneを５重量％含むよ うに、テトラヒドロフラン６５重量％とトルエン３５重量％とを含む混合物中に SaranF２７９樹脂とPellethane２３５４−８０Ａ１とを溶かすことによって遮断 材料の被膜を調製した。コーテッド水溶性フィルムの表面に塗布量４gm/m2（厚 さ約０．１ミル）で被膜を適用し、１１０℃で２分間乾燥させて、溶媒を除去し 、被膜を結晶化させた。得られた多層遮断フィルムは、３００°Ｆ、３０psi、 １秒保圧で９６．３Ｎ（１．４１lb）のヒートシール強度、および１３．１cc/m2 /H・atmの酸素透過度を有していた。 ある種の代表的な態様及び説明によって本発明を説明して来たが、添付の請求 の範囲で規定されている発明の範囲から逸脱することなく、本明細書で開示した 方法及び装置に関して様々な変更を加えることができることは当業者には明らか である。Detailed Description of the Invention                    Multilayer barrier film for fistula applications   The present invention is an oxygen and moisture impermeable coextruded or coated multilayer barrier. A film, and various manufactured from said multilayer barrier film. Ostomy bags for packaging various materials and heat sealable It relates to products including various bags.   Plastic film laminates that have barrier properties against oxygen and water vapor are currently available. For the conditions required for packaging, as well as for use in medical applications, eg It was desirable for the secondary processing of fistula bags. The film has at least a few layers Use a multilayer film laminate, one of which is impermeable to oxygen and water vapor. And provided by. Typically, the film is chlorinated polyethylene Film or plasticized polyvinyl chloride film, polyvinylidene chloride copolymer film Film or multi-layer structure, eg ethylene vinyl acetate / polyvinylidene chloride And a film in which ethylene vinyl acetate is combined. The structure is acid Sufficiently fills the basic and moisture barrier needs, but is often It was difficult to dispose of it in a convenient way (for example, to flush the bag in the toilet).   Martini et al., US Pat. No. 4,906.495, for use in fistula applications It relates to a laminated film. The barrier layer and the water-soluble layer are additional adhesive layers. Must be glued together using. The additional layers described above allow the material and manufacturing Not only does the strike increase, but a thicker film laminate with greater rigidity It will be manufactured.   US Pat. No. 4,772,279 by Brook et al. And US Patent by Coombes et al. No. 4,917,689 is a water-soluble outer layer made of polyvinyl alcohol, Disposable ostomy bar with a relatively insoluble inner layer of vinylidene chloride It's about the dog. Similarly, British Patents 2.083.762 and 2. Nos. 193,925 both disclose disposable disposable ostomy bags that include a water-soluble layer and a barrier layer. Explaining.   However, many of the current prior art multilayer films are heat sealable. Since it has no active surface, for example a barrier layer on only a small part of the film Requires a complicated method to fabricate the bag, such as placing . In addition, many multilayer films stack layers so that the layers support each other. Need glue. Therefore, no additional adhesive layers and laminating steps are required. A multi-layer insulation filter that can be manufactured by simpler and cheaper conventional methods. Need for rum, impermeable to moisture and oxygen, and odor barrier Multi-layer insulation with heat-sealable surface for providing heat resistance and making bags etc. Needs for films still exist.   The present invention does not require a separate adhesive layer to secure the other layers together, a simultaneous pressing. Oxygen and moisture impermeable multi-layer shields that can be produced by a coating or coating technique. The above need is satisfied by providing a cut film. The present invention Rum has excellent interlayer adhesion, excellent odor barrier, and for the secondary processing of bags. To provide a heat-sealable surface.   According to one aspect of the invention, at least 1. per inch of film width. Oxygen and moisture impermeable with heat seal strength greater than 0 lb, preferably 1.5 lb A temporary multilayer barrier film was provided. "Oxygen impermeable" means the film is 90cc / m2It means that it has an oxygen permeability of less than / H · atm. "Water impermeable Means that the film is 5gm / m2/ H means having a water vapor transmission rate of less than or equal to I have.   In one aspect of the invention, the film of the invention is made of water for use in an ostomy procedure. Coextruded with soluble film layer or coated on water soluble film layer It includes a barrier layer consisting of a vinylidene chloride homopolymer or copolymer. Preferably The water-soluble layer is a water-soluble polymer such as polyvinyl alcohol or polycapro Includes kutone or blend of polyethyloxozaline and thermoplastic polyurethane . Preferably, the water soluble layer is thicker than the barrier layer and is a thermoplastic polyurethane. 1-50% by weight, more preferably 10-25% by weight of thermoplastic polyurethane Including. The water-soluble film may be a single layer, or a water-soluble polymer and thermoplastic The first layer containing a blend with polyurethane and the same or different water-soluble polymer It can include two or more layers, with a second layer including, whereby the water of the film is The solubility is improved.   Furthermore, the adhesion between the water-soluble layer and the barrier layer can be improved using many means. Can be. As a means for them, a thermoplastic polyurethane layer is used for the water-soluble layer. An amount of thermoplastic polyurethane which is coated or coextruded or which improves adhesion And a blocking layer. The film obtained is 90cc / m2/ H ・ atm not Has full oxygen permeability. The barrier layer can be discarded with the barrier film facing inwards Formulated to heat seal to itself to make a bag.   In another form of this aspect of the invention, further, the barrier film is opposite the water-soluble layer. Any heat consisting of a suitable adhesive resin containing for example thermoplastic polyurethane on its side A sealable skin layer can be included. By the above layers, to the film And improved heat sealability is provided.   The multilayer barrier film of the present invention also stacks layers without the use of additional adhesive layers. It has sufficient bonding to allow coextrusion or coating without overlapping. And was discovered. In addition, the properties of the resulting film are either disposable or reusable. As an active fistula pouch and for pesticides, detergents and other household chemicals Suitable for use as.   Therefore, the feature of the present invention is that it can be manufactured by using a coextrusion method or a coating method. Was to provide an oxygen and moisture permeable multilayer barrier film. further, The features of the present invention include odor-blocking properties and heat resistance produced from the film of the present invention. And the ability to form pouches.   FIG. 1 shows a multi-layer of the present invention useful as a disposable stoma pouch containing a water-soluble layer. FIG. 7 is a schematic cross-sectional view of one embodiment of a barrier film;   2 is an ostomy bag or pack made from the multilayer barrier film of FIG. 1 of the present invention. It was a front view of my house.   The multilayer barrier film of the present invention uses a separate adhesive layer or a separate glue layer. Ancillary costs that are not required and are associated with extra manufacturing steps that occur during lamination. Stronger against layers than prior art laminated films without the need for Provides gluing. Therefore, the film can be used as a barrier film material for water-soluble fibrous materials. It can be manufactured by a coating method of coating on the rum layer. The resulting multi-layer fi Rum has low oxygen and water vapor permeability and is also required for fistula applications. It also has an odor blocking property. By practicing the invention, additional adhesive layers may be applied. Even if it is not selected and used or the components of each layer of the film are not blended, These properties can be achieved.   See FIG. Layer thickness is not to scale. Multilayer film 10 is water-soluble Salt coextruded with or coated on the transparent film layer 12 Homopolymer of vinylidene chloride, or vinylidene chloride and vinyl chloride or methyl For ostomy applications, including a barrier layer 14 consisting of a copolymer with methacrylate One embodiment of the present invention has been illustrated. Preferably, the water-soluble layer 12 is a water-soluble polymer , For example polyvinyl alcohol, polycaprolactone, or polyethyloxoza Includes a blend of phosphorus and thermoplastic polyurethane. The water-soluble layer 12 is typically , 1-50% by weight of thermoplastic polyurethane, more preferably 10-25% by weight Including. If desired, additional thermoplastic polyurethane may be added to the formulation to provide a barrier layer. The adhesion of the coating can be improved. However, the water solubility of the film is , Increase in the amount of thermoplastic polyurethane will be adversely affected, so be careful I won't. The water-soluble film can include one monolayer of the formulation, Co-extruding this formulation with another water-soluble polymer resin has improved water solubility It was also possible to produce a two-layer film.   A suitable barrier material is, for example, D under the trademark Saran® F279. Vinyl chloride (15-20% by weight) and salt commercially available from ow Chemical Company Mention may be made of copolymers with vinylidene chloride (80-85% by weight). Water soluble fill A water-soluble polyvinyl alcohol resin such as Air Products and Che Using Vinex® 5030 resin commercially available from micals, Inc. Can be. If a bilayer film with improved water solubility is desired, other water solubility Polyvinyl alcohol resin such as Vinex 2144 can be used. Two The above layers can be coextruded. When coextruding, the two layers are relative The film thickness can be adjusted to control the solubility of the film in water. The advantage that it can be obtained is obtained. For example, an unmodified water-soluble polymer resin layer is Containing up to 75% or more of a bilayer film to provide enhanced water solubility Can be.   As discussed above, 1-50% thermoplastic polyurethane is Can be blended with a polymer or other water-soluble polymer layer. Suitable thermoplastic Examples of the retan include polyisocyanate (aromatic or aliphatic), polyester, Thermoplastic poly based on reaction with polyether or polycaprolactone polyols Examples include urethane. Chain extenders such as diols and diamines can be used in the reaction. Can also be used. The above-mentioned thermoplastic polyurethane is Estane (registered trademark) ) Is commercially available from B.F.GoodrichCo. It is commercially available from Dow Chemical Company under the trademark. Preferred thermoplastic The polyurethane composition is Pellethane 2355-95AE.   As shown, an optional thermoplastic polyurethane skin layer 16 is added to the water soluble layer 12 Can be coextruded with or coated on the aqueous layer 12. Skin layer 1 6 and / or the thermoplastic polyurethane blended in the water-soluble layer 12 is It serves to strengthen the adhesion of the barrier layer 14 to the 2. The resulting film is 90cc / m2/ H ・ atm (6cc / 100in2It should have an oxygen permeability of less than / H · atm). This The higher oxygen permeability of the membrane makes it a barrier film designed to be disposable. Was acceptable. Fold it into a bag or pouch as shown. Multilayer film to provide improved heat sealability to the film when The rum is heat sealable on the side of the film opposite the water soluble layer 12. Any material consisting of a material such as thermoplastic polyurethane or other suitable adhesive resin A Kin layer 18 may be included.   FIG. 2 illustrates a typical waste containing opening 26 made from the multilayer barrier film of FIG. A possible stoma bag 20 is described. The bag is made of a multilayer film 10. It can be made by folding the edges and heat sealing the edges. Good More preferably, the bag or pouch 2 has a barrier layer and a heat-sealable skin layer. The film was folded and sealed so that 0 inner surface was provided. Cutoff of the present invention The film has the required waterproof, odor and oxygen barrier properties and is easily A disposable pouch for stoma surgery is provided. As appreciated by those skilled in the art Bright barrier film is suitable for other packaging applications where barrier properties against moisture and oxygen are required. You can also find its use.   The multilayer film of the present invention may be manufactured using conventional extrusion or coating techniques. Can be. When using a co-extrusion machine, change the shape of the extrusion die to The thickness and dimensions of the standing layer can be reduced. Therefore, the thickness of the multilayer film The height can be adjusted. A suitable coating device is a gravure coater. It is.   For coextrusion, the preferred embodiment of the water-soluble film is thermoplastic polyurethane. Combined with the improved water adhesion of polyvinyl alcohol resin Benefits were obtained. In the above coextrusion, a water-soluble polyvinyl alcohol layer, It was preferred to make it thick so that it was at least 75% of the total thickness of the film. Typical The water-soluble layer is 1-3 mils thick and the barrier layer is 0.1-0.2 mils.   However, it should be understood that many different layer combinations are possible. is there. For example, the film may consist of a water soluble polymer / thermoplastic polyurethane blend. First layer, a second layer made of thermoplastic polyurethane, and vinylidene chloride homopoly A barrier layer comprising a mer or copolymer can be included. With another possible combination For water-soluble polymers / thermoplastic polyurethane blends, and vinylidene chloride / It includes a barrier layer that includes a thermoplastic polyurethane formulation. Yet another combination is water Soluble polymer / thermoplastic polyurethane blend, layer consisting of thermoplastic polyurethane And a third layer comprising a polyvinylidene chloride / thermoplastic polyurethane blend. It was a three-layer film that was extruded at one time. Yet another possible combination is water First layer comprising soluble polymer / thermoplastic polyurethane blend, thermoplastic polyurethane A second layer containing a vinylidene chloride homopolymer or copolymer, And a fourth layer of thermoplastic polyurethane.   The following examples are provided so that the present invention can be understood more easily. under The examples are illustrative of the invention and are not intended to limit the scope of the invention.     Example 1   First of all, at 45 to 50 ° C., a thermoplastic polymer was added to tetrahydrofuran. The present invention was made by dissolving 5% by weight of Pellethane 2354-80A5. Thus, a multilayer film was manufactured. Next, thermoplastic polyurethane (Pellethane23 55-95AE) and extruded 2.0 mil thick polyvinyl alcohol. Rucor film (Vinex available from Air Products and Chemicals, Inc.) 5030) coating amount 2gm / m2Applied coating to a thickness of 0.05 mil . Place the coated film in an oven and dry at 120 ° C for 1.5 minutes. I let it.   Then, in a mixture containing 65% by weight of tetrahydrofuran and 35% by weight of toluene A coating of barrier material was prepared by melting Saran F279 in. Final lacquer Contained about 18% by weight Saran. Applied on the surface of coated water-soluble film Amount 4gm / m2Apply the coating (about 0.1 mil thick) and dry at 110 ° C for 2 minutes The solvent was removed and the film was crystallized. The resulting multilayer barrier film is 300 ° F, 30 psi, 1.7 sec (1.73 lb) heat seal strength at 1 second dwell, and 13.9cc / m2It had an oxygen permeability of / H · atm.     Example 2   Water-soluble film 85% Vinex 5030 and Pellethane 2355-95AE A multilayer film was prepared in the same manner as in Example 1 except that the content of 15% was included. Profit The resulting multilayer barrier film was 9.9 N (2. 22 lb) heat seal strength and 8.4 cc / m2/ H ・ atm oxygen permeability Was.     Example 3   First of all, at 45 to 50 ° C., a thermoplastic polymer was added to tetrahydrofuran. According to the present invention, 5% by weight of Pellethane 2354-80A1 was dissolved. To produce a multilayer film. Next, add 15% by weight of Pellethane 2355-95AE. Extruded 2.0 mil thick polyvinyl alcohol resin containing (Air Products a Vinex 5030) commercially available from nd Chemicals, Inc., coating amount of 2 gm / m2 Was applied to give a thickness of 0.05 mil. Orb that coated film And dried at 120 ° C. for 1.5 minutes.   Then the final lacquer contains about 18% by weight Saran and 5% by weight Pellethane. A mixture of 65% by weight of tetrahydrofuran and 35% by weight of toluene in a mixture. Blocked by melting Saran F279 resin and Pellethane 2354-80A1 A coating of material was prepared. Coating amount 4gm / m on the surface of coated water-soluble film2(Thickness Coating (about 0.1 mil) and dried at 110 ° C. for 2 minutes to remove solvent. , The film was crystallized. The resulting multilayer barrier film was 300 ° F, 30 psi, Heat seal strength of 96.3 N (1.41 lb) at 1 second holding pressure, and 13.1 cc / m2 It had an oxygen permeability of / H · atm.   Having described the invention by means of certain exemplary embodiments and description, the appended claims Disclosed herein without departing from the scope of the invention as defined by the It will be apparent to those skilled in the art that various changes can be made in the method and device. It is.

【手続補正書】特許法第１８４条の８ 【提出日】１９９５年４月１２日 【補正内容】 請求の範囲 １．塩化ビニリデンのホモポリマー、あるいは塩化ビニリデンと塩化ビニルま たはメチルメタクリレートとのコポリマーから成る遮断層を含み、前記遮断層が 水溶性フィルム層と共に同時押出されるかまたは水溶性フィルム層の上に塗布さ れ、また前記水溶性層が水溶性ポリマーと熱可塑性ポリウレタンとの配合物を含 む、フィルムの幅１インチ当たり少なくとも１．０lbのヒートシール強度を有す る多層遮断フィルム。 ２．該水溶性ポリマーが、ポリビニルアルコール、ポリカプロラクトン、また はポリエチルオキソザリンであった請求項１記載の多層遮断フィルム。 ３．該遮断層が、該遮断層中に配合されているかまたは該水溶性フィルム層と 接触している該遮断層の表面上に塗布されている、接着性を向上させる量の熱可 塑性ポリウレタンを含む請求項１記載の多層遮断フィルム。 ４．該フィルムが、９０cc/m2/H・atm未満の酸素透過度を有する請求項１記載 の多層遮断フィルム。 ５．該遮断層が、さらに、該水溶性層と反対側にある側面上に接着剤ポリマー 樹脂から成る層を含む請求項１記載の多層遮断フィルム。 ６．該接着剤ポリマー樹脂が、熱可塑性ポリウレタンであった請求項５記載の 多層遮断フィルム。 ７．該水溶性フィルム層が、該熱可塑性ポリウレタンを１０−１５重量％含む 請求項１記載の多層遮断フィルム。 ８．該水溶性フィルム層が、該熱可塑性ポリウレタンを１０−２５重量％含む 請求項１記載の多層遮断フィルム。 ９．該水溶性フィルム層が、２つの層、すなわち水溶性ポリマーと熱可塑性ポ リウレタンとの配合物を含む第一層、および水溶性ポリマーを含む第二層を含む 請求項１記載の多層遮断フィルム。 １０．該水溶性層が、該遮断層に比べて厚かった請求項１記載の多層遮断フィ ルム。 １１．該水分遮断層および該熱可塑性ポリウレタンをそれらの縁に沿ってヒー トシールして、バッグまたはパウチを作る請求項１記載の多層遮断フィルム。 １２．熱可塑性ポリウレタンから成る内層、およびポリビニルアルコールと熱 可塑性ポリウレタンとの配合物を含む水溶性フィルムから成る外層を含む多層水 溶性フィルム。[Procedure amendment] Patent Law Article 184-8 [Submission date] April 12, 1995 [Amendment content] Claims 1. A vinylidene chloride homopolymer, or a barrier layer consisting of vinylidene chloride and a copolymer of vinyl chloride or methyl methacrylate, said barrier layer being co-extruded with or coated on the water-soluble film layer, A multilayer barrier film having a heat-seal strength of at least 1.0 lb per inch of film width, wherein the water-soluble layer comprises a blend of a water-soluble polymer and a thermoplastic polyurethane. 2. The multilayer barrier film according to claim 1, wherein the water-soluble polymer is polyvinyl alcohol, polycaprolactone, or polyethyloxozaline. 3. The barrier layer comprises an adhesion-enhancing amount of a thermoplastic polyurethane incorporated into the barrier layer or coated on the surface of the barrier layer in contact with the water-soluble film layer. Item 1. The multilayer barrier film according to item 1. 4. The multilayer barrier film according to claim 1, wherein the film has an oxygen permeability of less than 90 cc / m 2 / H · atm. 5. The multilayer barrier film of claim 1, wherein the barrier layer further comprises a layer of adhesive polymer resin on the side opposite the water soluble layer. 6. The multilayer barrier film according to claim 5, wherein the adhesive polymer resin is thermoplastic polyurethane. 7. The multilayer barrier film according to claim 1, wherein the water-soluble film layer contains 10 to 15% by weight of the thermoplastic polyurethane. 8. The multilayer barrier film according to claim 1, wherein the water-soluble film layer contains 10 to 25% by weight of the thermoplastic polyurethane. 9. The multilayer barrier film of claim 1 wherein said water soluble film layer comprises two layers, a first layer comprising a blend of water soluble polymer and thermoplastic polyurethane and a second layer comprising a water soluble polymer. 10. The multilayer barrier film according to claim 1, wherein the water-soluble layer is thicker than the barrier layer. 11. The multilayer barrier film of claim 1, wherein the moisture barrier layer and the thermoplastic polyurethane are heat sealed along their edges to form a bag or pouch. 12. A multi-layer water-soluble film comprising an inner layer of thermoplastic polyurethane and an outer layer of a water-soluble film comprising a blend of polyvinyl alcohol and thermoplastic polyurethane.

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 庁内整理番号 ＦＩ Ｂ３２Ｂ 27/30 １０１ 9633−4Ｆ Ｂ３２Ｂ 27/30 １０１ 27/40 9349−4Ｆ 27/40 // Ｂ２９Ｋ 27:06 Ｂ２９Ｌ 7:00 9:00 ─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. 6 Identification code Internal reference number FI B32B 27/30 101 9633-4F B32B 27/30 101 27/40 9349-4F 27/40 // B29K 27:06 B29L 7:00 9:00

Claims (1)

【特許請求の範囲】 １．塩化ビニリデンのホモポリマー、あるいは塩化ビニリデンと塩化ビニル又 はメチルメタクリレートとのコポリマーから成る遮断層を含み、前記遮断層が水 溶性フィルム層と共に同時押出しされるか又は水溶性フィルム雇の上に塗布され 、また前記水溶性層が水溶性ポリマーと熱可塑性ポリウレタンとの配合物を含む 、フィルムの幅１インチ当たり少なくとも１．０lbのヒートシール強度を有する 多層遮断フイルム。 ２．該水溶性ポリマーが、ポリビニルアルコール、ポリカプロラクトン、又は ポリエチルオキソザリンであった請求項１記載の多層遮断フィルム。 ３．該遮断層が、該遮断層中に配合されているか又は該水溶性フィルム層と接 触している該遮断層の表面上に塗布されている、接着性を向上させる量の熱可塑 性ポリウレタンを含む請求項１記載の多層遮断フィルム。 ４．該フィルムが、９０cc/m2/H・atm未満の酸素透過度を有する請求項１記載 の多層遮断フィルム。 ５．該遮断層が、さらに、該水溶性層と反対側にある側面上に接着剤ポリマー 樹脂から成る層を含む請求項１記載の多層遮断フィルム。 ６．該接着剤ポリマー樹脂が、熱可塑性ポリウレタンであった請求項５記載の 多層遮断フィルム。 ７．該水溶性フィルム層が、該熱可塑性ポリウレタンを１０−１５重量％含む 請求項１記載の多層遮断フィルム。 ８．該水溶性フィルム層が、該熱可塑性ポリウレタンを１０−１５重量％含む 請求項１記載の多層遮断フィルム。 ９．該水溶性フィルム層が、２つの層、すなわち水溶性ポリマーと熱可塑性ポ リウレタンとの配合物を含む第一層、及び水溶性ポリマーを含む第二層を含む請 求項１記載の多層遮断フィルム。 １０．該水溶性層が、該遮断層に比べて厚かった請求項１記載の多層遮断フィ ルム。 １１．該水分遮断層及び該熱可塑性ポリウレタンをそれらの縁に沿ってヒート シールして、バッグ又はパウチを作る請求項１記載の多層遮断フィルム。 １２．熱可塑性ポリウレタンから成る内層、及びポリビニルアルコールと熱可 塑性ポリウレタンとの配合物を含む水溶性フィルムから成る外層を含む多層水溶 性フィルム。[Claims] 1. A barrier layer consisting of a vinylidene chloride homopolymer or a copolymer of vinylidene chloride and vinyl chloride or methyl methacrylate, said barrier layer being coextruded with a water-soluble film layer or applied on a water-soluble film layer, A multilayer barrier film having a heat seal strength of at least 1.0 lb / inch of film width, wherein the water soluble layer comprises a blend of a water soluble polymer and a thermoplastic polyurethane. 2. The multilayer barrier film according to claim 1, wherein the water-soluble polymer is polyvinyl alcohol, polycaprolactone, or polyethyloxozaline. 3. The barrier layer comprises an adhesion improving amount of a thermoplastic polyurethane incorporated into the barrier layer or coated on the surface of the barrier layer in contact with the water-soluble film layer. Item 1. The multilayer barrier film according to item 1. 4. The multilayer barrier film according to claim 1, wherein the film has an oxygen permeability of less than 90 cc / m 2 / H · atm. 5. The multilayer barrier film of claim 1, wherein the barrier layer further comprises a layer of adhesive polymer resin on the side opposite the water soluble layer. 6. The multilayer barrier film according to claim 5, wherein the adhesive polymer resin is thermoplastic polyurethane. 7. The multilayer barrier film according to claim 1, wherein the water-soluble film layer contains 10 to 15% by weight of the thermoplastic polyurethane. 8. The multilayer barrier film according to claim 1, wherein the water-soluble film layer contains 10 to 15% by weight of the thermoplastic polyurethane. 9. The multilayer barrier film of claim 1 wherein said water soluble film layer comprises two layers, a first layer comprising a blend of a water soluble polymer and a thermoplastic polyurethane, and a second layer comprising a water soluble polymer. 10. The multilayer barrier film according to claim 1, wherein the water-soluble layer is thicker than the barrier layer. 11. The multilayer barrier film of claim 1, wherein the moisture barrier layer and the thermoplastic polyurethane are heat sealed along their edges to form a bag or pouch. 12. A multilayer water-soluble film comprising an inner layer made of thermoplastic polyurethane and an outer layer made of a water-soluble film containing a blend of polyvinyl alcohol and thermoplastic polyurethane.
JP50977395A 1993-09-20 1994-08-26 Multilayer barrier film for fistula applications Pending JPH09506300A (en)

Applications Claiming Priority (3)

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US08/123,270 US5468526A (en) 1993-09-20 1993-09-20 Multilayer barrier film for ostomy applications
US08/123,270 1993-09-20
PCT/US1994/009682 WO1995008440A1 (en) 1993-09-20 1994-08-26 Multilayer barrier film for ostomy applications

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JPH09506300A true JPH09506300A (en) 1997-06-24

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US (1) US5468526A (en)
EP (1) EP0720531B1 (en)
JP (1) JPH09506300A (en)
KR (1) KR960704709A (en)
AT (1) ATE153597T1 (en)
AU (1) AU681906B2 (en)
CA (1) CA2172138A1 (en)
DE (1) DE69403487T2 (en)
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ES (1) ES2102247T3 (en)
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1119108A (en) * 1997-06-27 1999-01-26 Alcare Co Ltd Pouch for stoma outfit
JP4742386B2 (en) * 2006-01-16 2011-08-10 アルケア株式会社 Ostomy pouch, manufacturing method thereof, and ostomy appliance
JP2020527488A (en) * 2017-07-19 2020-09-10 カーマットＣａｒｍａｔ Flexible barrier film and method for manufacturing flexible barrier film

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346482A (en) * 1993-04-02 1994-09-13 Hollister Incorporated Two-piece ostomy appliance having flushable pouch and faceplate with protective collar
GB9406094D0 (en) * 1994-03-28 1994-05-18 Univ Nottingham And University Polymer microspheres and a method of production thereof
TW345540B (en) * 1994-08-31 1998-11-21 Nike Inc Laminated resilient flexible barrier membranes (1)
US5786092A (en) * 1994-11-21 1998-07-28 W.R. Grace & Co.-Conn. Peelable laminate
US5674578A (en) * 1994-12-27 1997-10-07 Hollister Incorporated Water soluble/dispersible multilayered film of high interlayer adhesive strength and collection pouches formed therefrom
GB2301038B (en) * 1995-05-25 1999-10-06 Ecoprogress Ltd A water-dispersible disposable enclosure
TW436517B (en) * 1995-07-27 2001-05-28 Morton Int Inc Aqueous latex adhesive-forming composition and method of making laminate
EP0769369B1 (en) 1995-10-09 2004-07-14 Kyodo Shiko Co., Ltd. Laminated film, method for production thereof, bag and package using the laminated film, and method for separation thereof
US6471401B1 (en) 1997-11-13 2002-10-29 Kyodo Shiko Co., Ltd. Laminated film, method for production thereof, bag and package using the laminated film, and method for separation thereof
USD409481S (en) * 1996-08-19 1999-05-11 The Coca-Cola Company Container
US5876331A (en) * 1996-11-12 1999-03-02 Johnson & Johnson Medical, Inc. Endoscope with improved flexible insertion tube
CA2288548A1 (en) 1998-12-11 2000-06-11 Kimberly-Clark Worldwide, Inc. Compositions of amorphous polyalphaolefin coatings on water-sensitive substrate
US6509072B2 (en) 1999-04-27 2003-01-21 P. Scott Bening Multi-layer film with periodic barrier coating and methods of making and using such film
US8166969B2 (en) * 2001-03-06 2012-05-01 Texas Research International, Inc. Chemically and biologically resistant hydration system
GB0121422D0 (en) * 2001-09-05 2001-10-24 Bioprogress Tech Int Inc Drainage bag
US20030116575A1 (en) * 2001-12-21 2003-06-26 Ellingson Daniel L. Disposable container with a spill prevention mechanism
US6783826B2 (en) 2001-12-21 2004-08-31 Kimberly-Clark Worldwide, Inc. Flushable commode liner
US6713140B2 (en) 2001-12-21 2004-03-30 Kimberly-Clark Worldwide, Inc. Latently dispersible barrier composite material
DK1684679T3 (en) * 2003-10-21 2009-10-12 Hollister Inc Peelable and transparent pouch and scope
US7179245B2 (en) * 2003-10-21 2007-02-20 Hollister Incorporated Flushable body waste collection pouch, pouch-in-pouch appliance using the same, and method relating thereto
US7819849B2 (en) * 2004-06-04 2010-10-26 Hollister Incorporated Laminated material and body wearable pouch formed therefrom
US7282273B2 (en) * 2005-10-26 2007-10-16 Polymer Ventures, Inc. Grease resistance and water resistance compositions and methods
JP2009517193A (en) * 2005-11-28 2009-04-30 ホリスター・インコーポレイテッド Washable waste collection pouch, improvements in pouch-in-pouch type articles using the pouch, and methods relating thereto
US20100121290A1 (en) * 2006-03-28 2010-05-13 Torben Rasmussen Multilayer Film
US8936583B2 (en) 2007-09-28 2015-01-20 Hollister Incorporated Multi-layer catheter tubes with odor barrier
US8734411B2 (en) * 2007-09-28 2014-05-27 Hollister Incorporated Multi-layer odor barrier tube, and combination odor barrier tube and odor barrier collection bag
US20090098303A1 (en) * 2007-10-15 2009-04-16 Polymer Ventures, Inc. Coatings to increase water and grease resistance of porous materials and materials having such protection
GB0806271D0 (en) * 2008-04-07 2008-05-14 Chemlink Specialities Ltd pakaging and method of manufacturing thereof
US8257720B2 (en) 2009-04-20 2012-09-04 Conopco, Inc. Stabilized cationic ammonium compounds and compositions comprising the same
US8287974B2 (en) * 2009-06-01 2012-10-16 Polymer Ventures, Inc. Polyol-based release paper, articles, and methods
US8273435B2 (en) * 2009-06-01 2012-09-25 Polymer Ventures, Inc. Polyol coatings, articles, and methods
US7939138B2 (en) * 2009-06-01 2011-05-10 Polymer Ventures, Inc. Grease resistant coatings, articles and methods
US8324255B2 (en) 2009-09-15 2012-12-04 Conopco, Inc. Chelator stabilized cationic ammonium compounds and compositions comprising the same
DE102009043310A1 (en) * 2009-09-29 2011-04-28 Constantia Hueck Folien Gmbh & Co. Kg Tear-resistant packaging composite film and packaging
US8399077B1 (en) 2011-11-21 2013-03-19 Cryovac, Inc. Polyglycolic acid-based film
US20130277261A1 (en) * 2012-04-23 2013-10-24 Perfecseal, Inc. Packaging for a Size Varying Series of Femoral Components for Artificial Knee Joints
HUE050969T2 (en) 2012-11-12 2021-01-28 Hollister Inc Intermittent catheter assembly
ES2793650T3 (en) 2012-11-14 2020-11-16 Hollister Inc Disposable catheter with selectively degradable inner core
ES2688532T3 (en) 2013-01-18 2018-11-05 Basf Se Acrylic dispersion based coating compositions
CA2910901C (en) * 2013-04-29 2018-03-20 Evonik Rohm Gmbh Elastomer pmma layered composites having improved properties
LT3862031T (en) 2013-11-08 2023-09-25 Hollister Incorporated Oleophilic lubricated catheters
HUE049637T2 (en) 2013-12-12 2020-09-28 Hollister Inc Flushable catheters
DK3620198T3 (en) 2013-12-12 2021-04-12 Hollister Inc EXCLUSIVE CATHETRES
AU2014363933B2 (en) 2013-12-12 2019-10-10 Hollister Incorporated Flushable disintegration catheter
US10420859B2 (en) 2013-12-12 2019-09-24 Hollister Incorporated Flushable catheters
WO2016205383A1 (en) 2015-06-17 2016-12-22 Hollister Incorporated Selectively water disintegrable materials and catheters made of such materials

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3221742A (en) * 1962-01-09 1965-12-07 Orowan Egon Receptacle for enterostomy appliance
US3753828A (en) * 1968-05-23 1973-08-21 Tee Pak Inc Method of preparing oxygen impermeable film laminate
US3801430A (en) * 1969-04-16 1974-04-02 Dow Corning Process for molding a flexible mold
BE790680A (en) * 1971-10-28 1973-04-27 Unilever Nv LAMINATED PLASTIC FILM
US3725120A (en) * 1971-12-13 1973-04-03 Goodyear Tire & Rubber Polyurethane container
US3790437A (en) * 1972-04-20 1974-02-05 Dayco Corp Polyvinyl alcohol fiber reinforced polyurethane compositions and products therefrom
GB1384791A (en) * 1972-04-28 1975-02-19 Grace W R & Co Laminates
US3900616A (en) * 1972-10-20 1975-08-19 Dow Chemical Co Process for coating a nonporous substrate with a vinylidene chloride polymer using a thermoplastic polyurethane precoat
US3934587A (en) * 1974-06-17 1976-01-27 Roy Gerald Gordon Disposable articles having a water-permeable and water-repellent surface
CA1157990A (en) * 1979-03-08 1983-11-29 Hisaya Sakurai Thermoplastic resinous composition
US4309332A (en) * 1979-04-02 1982-01-05 National Distillers & Chemical Corp. Ethylene-vinyl acetate copolymer rubbers
US4296156A (en) * 1979-12-26 1981-10-20 Union Carbide Corporation Multilayer film including a polyurethane
GB2083762B (en) * 1980-08-12 1985-02-20 Enak Ltd Wc disposable sheet material and containers made therefrom
US5108382A (en) * 1980-08-12 1992-04-28 Timbale Corporation Nv Disposable containers
US4376799A (en) * 1980-09-16 1983-03-15 The Dow Chemical Company Quiet film and container
JPS6059207B2 (en) * 1981-03-13 1985-12-24 日東電工株式会社 Manufacturing method for complex preparations
US4348437A (en) * 1981-06-10 1982-09-07 Union Carbide Corporation Puncture-resistant heat shrinkable multilayer packaging film
IT1163372B (en) * 1983-05-13 1987-04-08 Grace W R & Co LAMINATED FILMS WITH HIGH CHARACTERISTICS OF SILENCE AND SOFTNESS, IN PARTICULAR FOR CONTAINERS OR DRAINAGE BAGS FOR MEDICAL USE
US4735985A (en) * 1985-04-08 1988-04-05 Minnesota Mining And Manufacturing Company Chip- and abrasion-resistant polyurethane coating composition having improved adhesion
JPS61241135A (en) * 1985-04-19 1986-10-27 旭化成株式会社 High-frequency adhesive polyurethane foam
DE3642150C2 (en) * 1986-01-17 1993-12-23 Smiths Industries Plc Ostomy bags for body waste
GB2193925B (en) * 1986-08-18 1990-07-04 Enak Ltd Improvements relating to wc-disposable sheet material
GB8620778D0 (en) * 1986-08-28 1986-10-08 Smiths Industries Ltd Medico-surgical articles
US4762738A (en) * 1986-12-22 1988-08-09 E. R. Squibb & Sons, Inc. Means for disposal of articles by flushing and ostomy pouches particularly suited for such disposal
GB8630863D0 (en) * 1986-12-24 1987-02-04 Grace W R & Co Laminated articles
GB8703874D0 (en) * 1987-02-19 1987-03-25 Smiths Industries Plc Ostomy bags & materials
GB2212167A (en) * 1987-11-10 1989-07-19 Craig Med Prod Ltd Adhesive composition
JP2583084B2 (en) * 1987-12-17 1997-02-19 日本合成化学工業株式会社 Waste container
GB8729637D0 (en) * 1987-12-19 1988-02-03 Smith Ind Plc Collection bags
US5009648A (en) * 1989-03-22 1991-04-23 E. R. Squibb & Sons, Inc. Starch containing film ostomy pouches
US4983171A (en) * 1989-07-14 1991-01-08 W. R. Grace & Co.-Conn. Comfortable ostomy pouch
US5028648A (en) * 1990-07-12 1991-07-02 Air Products And Chemicals, Inc. Extrudable polyvinyl alcohol compositions containing thermoplastic polyurethane
EP0474173B1 (en) * 1990-09-04 1996-04-10 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Biodegradable melt-molded articles and laminates derived therefrom, and their use
GB9112912D0 (en) * 1991-06-14 1991-08-07 Smiths Industries Plc Medico-surgical and sanitary articles and materials
JP3212044B2 (en) * 1992-08-07 2001-09-25 株式会社クラレ Manufacturing method of multilayer structure

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1119108A (en) * 1997-06-27 1999-01-26 Alcare Co Ltd Pouch for stoma outfit
JP4742386B2 (en) * 2006-01-16 2011-08-10 アルケア株式会社 Ostomy pouch, manufacturing method thereof, and ostomy appliance
JP2020527488A (en) * 2017-07-19 2020-09-10 カーマットＣａｒｍａｔ Flexible barrier film and method for manufacturing flexible barrier film

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EP0720531A1 (en) 1996-07-10
DE69403487T2 (en) 1997-12-18
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AU7639794A (en) 1995-04-10
WO1995008440A1 (en) 1995-03-30
DE69403487D1 (en) 1997-07-03
AU681906B2 (en) 1997-09-11
US5468526A (en) 1995-11-21
KR960704709A (en) 1996-10-09
ES2102247T3 (en) 1997-07-16
ATE153597T1 (en) 1997-06-15
CA2172138A1 (en) 1995-03-30
EP0720531B1 (en) 1997-05-28
DK0720531T3 (en) 1997-12-22

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